(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Loaded
Definition:
(imp. & p. p.) of Load
Example Sentences:
(1) After a period on fat-rich diet the patient's physical fitness was increased and the recovery period after the acute load was shorter.
(2) The only sign of life was excavators loading trees on to barges to take to pulp mills.
(3) Spermine clearly activated 45Ca uptake by coupled mitochondria, but had no effect on Ca2+ egress from mitochondria previously loaded with 45Ca.
(4) In the case of nonspecific loading highly trained individuals may have low VT values close to the level characteristic for normal subjects.
(5) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(6) Excretion of inactive kallikrein again correlated with urine flow rate but the regression relationship between the two variables was different for water-load-induced and frusemide-induced diuresis.
(7) With this system, a brain region loaded with fura-2 was illuminated by a rotating disc bearing three different interference filters of 340, 360 and 380 nm at a rate of 600 rpm.
(8) Eddy current transducers measured relative displacements under application of static loads, serially applied in the axial, mediolateral, and craniocaudal directions.
(9) Over the course of 26-40 h the Na- and water-loaded cells returned to a normal state of hydration as judged by their density.
(10) Subjects who trained an additional 52 wk showed a slight drop in SV at submaximal work loads from the initial increase following the first 9 wk.
(11) For the non-emergency admissions, the low-load physicians' patients had an average LOS that was 56.2% greater and an average hospital cost that was 58.3% greater than were the LOS and cost of the patients of the high-load physicians.
(12) The presence of an inverse correlation between certain tryptophan metabolites, shown previously to be bladder carcinogens, and the N-nitrosamine content, especially after loading, was interpreted in view of the possible conversion of some tryptophan metabolites into N-nitrosamines either under endovesical conditions or during the execution of the colorimetric determination of these compounds.
(13) The effects of supervised mild aerobic exercise at the work load of the blood lactate threshold for 10 weeks on serum lipids and apolipoproteins were studied in 24 patients with essential hypertension.
(14) In the water-loaded state, MAP rose significantly at the lowest rate of infusion in both pregnant and non-pregnant ewes.
(15) Respiratory muscle endurance at a given level of load was assessed from the time of exhaustion and from the time course of the change in the power spectrum (centroid frequency) of the diaphragm electromyogram (EMG).
(16) Regressional analysis of relations between loads and the level of inbreeding in the Adyg population showed the explicit interrelation between the load of autosomal-dominant diseases and the Fst correlation coefficient being 0.89.
(17) 9 Women performed plantarflexion and dorsalflexion with maximum strength and at constant load of 60% MVC to exhaustion.
(18) In PSS amiloride and EIPA each had a small inhibitory effect on the pH recovery after an acid load.
(19) Also blacks differ from whites in 2 ways that could be relevant for their increased prevalence of hypertension: they excrete sodium loads more slowly and have a markedly lower urinary kallikrein.
(20) Calcium loading to erythrocytes in vitro caused a greater decrease in the membrane fluidity in essential hypertension than in the normotensive controls.