(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Somber
Definition:
(v. t.) Alt. of Sombre
(a.) Alt. of Sombre
(n.) Alt. of Sombre
Example Sentences:
(1) Melanomas developed on giant pigmented naevi had a particularly somber prognosis: death occurred within 6, 7 and 3 months respectively in the 3 cases observed.
(2) Uncompleted mourning and the depression and somber states of mind it created were absorbed by their children from birth on.
(3) In these very old people with very somber prognosis, anemia was corrected by surgery without recurrence after 8 and 10 months respectively.
(4) If Trump seems strangely incapable of consistency except in the matter of walling out and deporting immigrants, somber Ted Cruz is lurking nearby to alarm us with his ideological purity.
(5) Although most readers consider medical publications to be somber and somnifacient, a critical eye will discover a remarkable array of absurdities and assorted other oddities, totally unintended by the authors.
(6) Almost every report on macular degeneration begins with a somber reminder that macular degeneration is the single most common cause of blindness in the elderly in the United States and Europe.
(7) 'A lot of the movements to combat violence against women are somber.
(8) Coronary lesions with atheromatous deposits occurring in later childhood characterize homozygous type IIa hypercholesterolaemia and condition the somber prognosis of a disease which affects one subject in a million.
(9) The statement read: It is with a heavy heart and somber mind that we remember and honor the victims, survivors, heroes of the Holocaust.
(10) The day after the election, I walked around the camp and it was really somber,” said Kandi Mossett, a member of the Mandan, Hidatsa and Arikara tribes who has been camping at Standing Rock since mid-August.
(11) The mood was somber, and many people wiped away tears.
(12) She suggests that the question for anyone considering standing for the US presidency should be: “What’s your vision for America?” Then she supplies her own answer: “The challenge is to lead in a way that unites us again and renews the American Dream … Ultimately, what happens in 2016 should be about what kind of future Americans want for themselves and their children – and grandchildren.” The start of the book is more somber.
(13) Since President Barack Obama took office, there have been at least 16 major mass shootings, after which he has offered somber words of condolence and called for national healing.
(14) In 1811 Mary Reynolds, a somber Pennsylvania spinster, awoke from a prolonged sleep as a new personality.
(15) This discussion forms the basis of a review of the worldwide literature, but stresses two problems which determine the prognosis: that of diagnosis, which in the majority of cases is very late, and that of their prognosis, which remains somber because of their tendency to metastasize by blood-borne spread and that of locoregional recurrences.
(16) In a strong but somber voice, McDonnell told the judge before sentencing that he was “a heartbroken and humbled man” and that he holds himself accountable.
(17) In other essays, she tries to educate a caddish boyfriend by sharing wisdom from He’s Just Not That Into You , and unexpectedly surrenders to the madness of wedding gown shopping, in which “dresses are brought out from back rooms with somber reverence, like the Torah being revealed from the ark”.
(18) She did not answer a question about whether Trump did not want to offend people, saying only: “It was our honor to issue a statement in remembrance of this important day.” In its original statement, the White House said: “It is with a heavy heart and somber mind that we remember and honor the victims, survivors, heroes of the Holocaust .
(19) At the International Brotherhood of Electrical Workers Local 369 hall in Louisville, where supporters had hoped to celebrate a Grimes win, the mood quickly turned somber: one minute, a few young employees were playing stickball while waiting for the party to start, and the next the hall was empty, as the few people who had arrived before the race was called went up to the war room to commiserate and watch the results of the statehouse races.
(20) Despite significant advances in many areas, the morbidity and mortality statistics remain as somber reminders of the devastation attributed to this epidemic.