(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
(superl.) Firm; tough; materially strong; enduring; as, a stout vessel, stick, string, or cloth.
(superl.) Large; bulky; corpulent.
(n.) A strong malt liquor; strong porter.
Example Sentences:
(1) Second, Stout felt that the high mitotic rate was the best predictor of malignancy, but he recognized that some tumors, even with low rates, could metastasize.
(2) The cell bodies are usually between 8 and 10 mu in diameter and have dividing pseudopodial processes which may be broad or narrow, flat or stout, smooth or varicosed.
(3) The Lib Dems and Labour, after frantic consultations, announced they would table alternative amendments to introduce an element of statute and ensure the new press regulatory body was free from industry interference – two issues that the majority of newspaper proprietors have stoutly opposed.
(4) It also highlights law professor Lynn Stout’s recent book, The Shareholder Value Myth .
(5) Stout – even the name is robust: broad-mouthed and curtly clipped at the end.
(6) Tune into BBC1 on Sunday morning and you will find the corporation complicit in Marr's convalescent strategy of stout denial.
(7) Against my will I had to keep watching those two black companions who persistently marked out our movements ahead of us, like walking silhouettes, and it gave me – our feelings are sometimes so childish – a certain reassurance to see that my shadow was longer, slimmer, I almost said "better-looking", than the short, stout shadow of my companion.
(8) A stout man with close-cropped hair, Jones was dressed in denim, his temples soaked with sweat.
(9) Heat the sugar, cocoa powder, double cream, stout and salt in a small pan until scalding.
(10) Aside from history enthusiasts and couples seeking privacy from the crowded city, few enter the red sandstone gate between the fort’s stout bastions.
(11) Chocolate stout pudding (above) Admittedly, with summer creeping in and temperatures rising, it's hardly pudding season.But I'm a firm believer in the restorative powers of stodge, and I'd hate for the pleasures of pudding – steamed sponges, sticky toffee, spotted dick and custard – to be out of bounds for part of the year.
(12) This investigation is a replication and extension of an earlier study by Stout, Holmes, and Rothstein (1977) of the predoctoral clinical psychology intern graduates at the William S. Hall Psychiatric Institute.
(13) The differential diagnosis of the morphological substrate is discussed and the preference of the termination introduced by Stout and Lattes is established.
(14) The pyriform cells had a short stem from which extended 4-5 stout dendrites, while the fusiform cells extended similar dendrites from the soma.
(15) All these characters are fictionalised, but they are based on real people: Frank Stokes is modelled on George Stout ; Campbell on Robert K. Posey ; Garfield on Walker Hancock ; Granger on James Rorimer .
(16) There’s nothing flash or trendy about it, just an immaculate, traditionally brewed, higher alcohol stout; a reminder that, for all the cool stuff going on in the beer world today, you can always learn from the past.
(17) At the pub on the island there was a concertina-player and we got the feeling – fuelled by pints of rich dark stout – that we were being absorbed into a community.
(18) The stout-candied air, high beams and heavy pews are reminiscent of church-scale pubs on Galway’s Quay Street, but the beams are hung with Arthurian standards.
(19) Cysteines 358, 421, and 424 are ligands to the Fe-S cluster in the inactive [3Fe-4S] (Robbins, A. H., and Stout, C. D. (1989) Proteins 5, 289-312) and active [4Fe-4S] (Robbins, A. H., and Stout, C. D. (1989) Proc.
(20) Solid and traditional, all acres of dark wood and stained glass, it prides itself on its list of around 18 mainly bottled Irish beers from such breweries as Kinsale, Hilden, Station Works, Farmageddon, Clever Man (look out for its Ejector Seat turf-smoked stout) and Hercules.