(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Weighty
Definition:
(superl.) Having weight; heavy; ponderous; as, a weighty body.
(superl.) Adapted to turn the balance in the mind, or to convince; important; forcible; serious; momentous.
(superl.) Rigorous; severe; afflictive.
Example Sentences:
(1) It is appropriate that AIDS be responded to as a crisis, but we also have a weighty, preexisting set of long-standing and equally lethal health and social ills.
(2) Weighty stuff, but critics hailed the show as the neurotic standup’s best in years.
(3) They imply that it is a matter of weighty regret that things have now reached a pass where their only conscionable option is to declare "thus far and no further".
(4) 4S, 5S, AND 18S + 28S RNA from the newt Taricha granulosa granulosa were iodinated in vitro with carrier-free 125I and hybridized to the denatured chromosomes of Taricha granulosa and Batrachoseps weighti.
(5) We'll be here until then and beyond, sharing every rumour nugget, insightful news line and weighty analysis we can muster.
(6) Little ones might freak out a bit at the wax characters and the gloomy dark but this is a fun way to bring a fairly weighty school text to life.
(7) In contrast, D changed from left weightiness to symmetry, coinciding with improvement but not with deterioration, With reference to the latter findings we discuss the possibility of a particular mode of cerebral lateralization predisposing to endogenous depression.
(8) The DPA is a weighty US drug policy reform NGO that can boast tycoons such as George Soros and Richard Branson and celebrities including Sting on its board of directors.
(9) Then there were the imported dramas broadcast because they were weighty, such as 1984's Heimat , an enthralling dramatisation of ordinary lives in 20th-century Germany.
(10) At the time of his resignation he had far more weighty matters filling his in-tray than the NRB case, not least a probe into alleged corruption among some of Boris Yeltsin's close relatives.
(11) Brennan bridles at that, saying it would be "a very weighty decision in terms of declassifying that report."
(12) In the Nederlandsch Tijdschrift voor Geneeskunde the last-mentioned aspect appears to have been very weighty, especially in the beginning.
(13) Weighty, expensive impact reports sit hidden deep within websites (or worse, annual reports), while the public remains oblivious to what happens to donations.
(14) They're running almost entirely on biscuits and cans of Red Bull, kept awake by a mix of jokes, weighty debate, and general good humour.
(15) It's an extra nerdy and intelligent version too, with tactical jedi Jonathan Wilson and his young apprentic Zonal Marking's Michael Cox there to provide the yuks and giggles as myself and James Richardson analyse the weighty football issues of the day to within an inch of their lives.
(16) The world will long remember their son Edward as the heir to a weighty legacy; a champion for those who had none; the soul of the Democratic party; and the lion of the US Senate – a man whose name graces nearly one thousand laws, and who penned more than 300 himself.
(17) It was the world of John Smith, razor-sharp debating, forensic examination of weighty issues and Gaitskellite intrigues.
(18) A comparison between the activity of the two hands yielded a pronounced left-weightiness of object-focused, continuous body-focused and discrete body-focused movements in contrast to findings on normal persons.
(19) The chancellor demanded that officials develop weighty evidence about whether or not the new 50p rate was working.
(20) The science report is the first of three major IPCC reports this year; similarly weighty analysis of the impact and possible solutions will follow in April and May respectively.