(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Woe
Definition:
(n.) A curse; a malediction.
(a.) Woeful; sorrowful.
(n.) Grief; sorrow; misery; heavy calamity.
Example Sentences:
(1) The disappointing weather at Easter left beaches deserted but some Britons, who were determined to enjoy the outdoors this time round, have already had their plans thwarted by the weather, taking to websites such as ukcampsite.co.uk to swap tales of woe, such as farmers calling to cancel bookings because sites were waterlogged.
(2) If I’m the bad guy because I’m not the guy they want me to be, then so be it.” Over the last year he resolved his promotional woes in court and has since signed with Jay Z’s Roc Nation Sports – along with Miguel Cotto the nascent sports agency’s highest-profile signing in boxing.
(3) While Chinese media have not spelt out Zhou's woes explicitly, the hints have grown more blatant by the month, with some identifying him via his family relationships.
(4) Asked if Aamer would talk publicly about his experiences, Crider said: “I think he will make up his own mind about it, and really, woe betide the person who tries to silence Shaker Aamer.” She added that it would be up to him “how much of his story and the terrible things he witnessed that he wants to tell”.
(5) Plummeting oil prices only added to economic woes in a country with the world’s fourth-largest oil reserves.
(6) To add to their woes, the cost of their dollar-denominated debt is rising; the US Federal Reserve said December’s rate hike is just the start of a “gradual” tightening cycle .
(7) It’s a seismic moment for the industry and particularly the big European manufacturers who have done a lot of work on diesel: technologically, they have they made the wrong bet.” Some analysts believe fears of brand damage in Europe are overstated but Bailey says: “In the US it’s very different: VW have killed their diesel market and it has left them in a very difficult position.” For British manufacturer Jaguar Land Rover, the timing of VW’s woes was ominous, as it unveiled two new diesels in America.
(8) The aluminium magnate's British-related woes do not stop there: a former business partner, Michael Cherney, is suing him for $4bn in the high court.
(9) We have to acknowledge that it's extremely hard to build a regular city from scratch.” Furthermore, some experts say that certified green buildings and pedestrian-friendly roads are a worthless patch for China’s environmental woes, not a solution.
(10) The woes of British industry were echoed right across Europe in November, as firms slashed production amid plunging demand from consumers in all the world's major markets.
(11) Clinton said her woes over her email server had been a “drip, drip, drip” that was impacting her.
(12) In an otherwise assured performance on Sunday’s Andrew Marr Show , Douglas Alexander – when urged to address Ed Miliband’s woes – resorted to the words of Harold Wilson.
(13) Buhari has presented himself as a born-again democrat who possesses the experience to steer the country through instability, currency woes and rampant corruption.
(14) Creative diplomacy is still much required in the Middle East, where it is hard to see how a dominantly military strategy against Islamic State can in itself, and even over time, bring a solution to the region’s woes.
(15) The unrest over rising petrol prices is only further adding to Nigeria's security woes: Jonathan already declared a state of emergency over the weekend in parts of the country hit by a growing Islamic insurgency that is fuelled in part by widespread poverty.
(16) But that may be the least of Ukip’s woes as it sups the bitter draught of victory.
(17) 7.31pm BST Nick Kyrgios's legs have gone to jelly and his heart is full of woe.
(18) It is not the cause of Spain's economic woes, but think of this: if everybody paid their dues, Spain's deficit would be zero.
(19) The result in some richer countries has been a political movement that blames globalisation for all woes and seeks somehow to wall off the economy from global trends rather than engage cooperatively with foreign nations.
(20) Probably... April 23, 2013 11.42am BST Analysts see little relief for Europe The continuing fall in Eurozone output this month ( see 9.19am ) led by Germany's shrinking private sector seconomy, shows that there's no improvement in Europe's woes.