(n.) A nonplane curve whose tangents are all equally inclined to a given plane. The common helix is the curve formed by the thread of the ordinary screw. It is distinguished from the spiral, all the convolutions of which are in the plane.
(n.) A caulicule or little volute under the abacus of the Corinthian capital.
(n.) The incurved margin or rim of the external ear. See Illust. of Ear.
(n.) A genus of land snails, including a large number of species.
Example Sentences:
(1) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
(3) The C-terminal sequence contains an amphiphilic alpha-helix of four turns which lies on the surface of the beta-barrel.
(4) The chiral intercalators, at micromolar concentrations, inhibit the reaction of EcoRI, but for each enantiomeric pair it is the lambda enantiomer, which binds only poorly to a B-DNA helix, that inhibits EcoRI preferentially.
(5) The melting profile exhibited two transitions--one at about 35 degrees C and one above 50 degrees C. Our spectral data showed that helices I and II were stable during the first transition, and agreed with other data that helix III was the most likely helix to have melted.
(6) The helix axes, penetrating the hydrophobic region of the bilayers, were oriented neither parallel nor perpendicular to the membrane normal.
(7) The structure of the Z-helix antigen was confirmed by circular dichroism (CD) and U.V.
(8) Conformational predictions based on these sequences confirm their structural homology and indicate the probable existence of two beta-turns, one beta-chain and a long alpha-helix in them.
(9) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(10) The latter, which is external and solvent accessible, is associated with a distortion in the alpha-helix centered around Tyr33 which consists of a significant increase in the CO(i-4)-N(i) and CO(i-4)-NH(i) distances relative to those in the rest of the helix, as well as a significant departure in the phi, psi angles of Tyr33 relative to regular helical geometry.
(11) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(12) MP8 also was conformed as an alpha-helix, but was amphipatic in the sense that the N-terminal half of the molecule was hydrophilic and the C-terminal half hydrophobic.
(13) A lectin, Helix pomatia agglutinin (HPA), was planted at the surface of rat GEN by the perfusion of the isolated left kidney with neuraminidase (NRD) and HPA.
(14) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(15) The opsin mutations included reversal of a charged pair conserved in all G protein-coupled receptors at the cytoplasmic border of the third transmembrane helix (mutant CD1), replacement of 13 amino acids in the second cytoplasmic loop (mutant CD2), and deletion of 13 amino acids from the third cytoplasmic loop (mutant EF1).
(16) The remaining 26 independently isolated second-site suppressor mutations all mapped within the amino-terminal DNA binding domain of LexA, at positions 22 (situated in the turn between helix 1 and helix 2) and positions 57, 59, 62, 71 and 73.
(17) In subsequent steps, unassociated Y' directs the synthesis of the complementary oligopurine (R') strand forming a new double helix Y'R' that may direct the synthesis of an oligopyrimidine strand, Y, that is expected to be identical to the first strand that started the whole sequence.
(18) Z-DNA antigen was prepared against poly(dG-dC).poly(dG-dC), which had been converted to the Z-helix conformation in high salt and then stabilized by bromination.
(19) Incubation and heating of the polymers in 1 mM Mn2+ caused the spectral shift reported for the left-handed Z-DNA conformation in the alternating copolymer and the change reported for the triple helix in the homopolymer.
(20) To investigate the ability of a protein to accommodate potentially destabilizing amino acid substitutions, and also to investigate the steric requirements for catalysis, proline was substituted at different sites within the long alpha-helix that connects the amino-terminal and carboxyl-terminal domains of T4 lysozyme.
Perpendicular
Definition:
(a.) Exactly upright or vertical; pointing to the zenith; at right angles to the plane of the horizon; extending in a right line from any point toward the center of the earth.
(a.) At right angles to a given line or surface; as, the line ad is perpendicular to the line bc.
(n.) A line at right angles to the plane of the horizon; a vertical line or direction.
(n.) A line or plane falling at right angles on another line or surface, or making equal angles with it on each side.
Example Sentences:
(1) Our data support the hypothesis that evoked and epileptiform magnetic fields result from intradendritic currents oriented perpendicular to the cortical surface.
(2) Right ventricular volumes were determined in 12 patients with different levels of right and left ventricular function by magnetic resonance imaging (MRI) using an ECG gated multisection technique in planes perpendicular to the diastolic position of the interventricular septum.
(3) We attribute the greater strength of the step-cut repair to the additional number of epitendinous loops, which lie perpendicular to the long axis of the tendon.
(4) The helix axes, penetrating the hydrophobic region of the bilayers, were oriented neither parallel nor perpendicular to the membrane normal.
(5) We show that over a limited range of high spatial frequencies this noise takes on a striated appearance, with the striations running perpendicular to the true fringe orientation.
(6) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(7) The two molecules in the asymmetric unit form a dimer with its 2-fold axis perpendicular to and intersecting with a crystallographic 4(1) axis.
(8) Interestingly, the helical motif prefers to assemble parallel to the wall, whereas the beta-barrel, predominantly assembles with its principal axis perpendicular to the wall.
(9) The numerals were either upright, or inverted, or rotated perpendicular to the arm axis.
(10) Parameters measured from simulator films included: (a) the perpendicular distance from the posterior tangential field edge to the posterior part of the anterior chest wall at the center of the field (CLD); (b) the maximum perpendicular distance from the posterior tangential field edge to the posterior part of the anterior chest wall (MLD); and (c) the length of lung (L) as measured at the posterior tangential field edge on the simulator film.
(11) Our results suggest that the first stage is much more selective for orientation than are lateral geniculate nucleus cells, but that the first-stage orientation bandwidth is rather wide with some interaction occurring between perpendicular orientations.
(12) In slices cut parallel to the pyramidal neurons (perpendicular to the brain surface) one can study chemosensitivity of the various parts of the dendritic tree and the soma.
(13) The bands encircle the muscle fiber perpendicular to the long axis of the fiber and they matched the sites of attachment of the sarcomeres to the plasma membrane.
(14) Thin section analysis of capped cells revealed an abundance of microtubules immediately beneath the cap which were arranged approximately perpendicular to the plane of the membrane.
(15) This procedure allowed both light and electron microscopic examination of serial-step sections of individual cells cut in a plane perpendicular to the monolayer.
(16) If a segment of a line differs in luminance or color from the rest of the line, three illusory phenomena may be perceived: a reduction in contrast of the line segment relative to the background, subjective contours running perpendicularly to the ends of the line segment, and spread of color or brightness surrounding the line segment.
(17) Typically they lie perpendicular to the cell membrane of the pinealocyte polar process and in close proximity to a polar process of a neighboring cell.
(18) The results of the scattering experiments were almost independent of whether the NaDNA fibers were oriented parallel or perpendicular to the momentum transfer.
(19) Instruments should be rotated perpendicular to the margin from gold to enamel.
(20) The method uses overlapping of Pi1, 3 and 4 in perfect centering of the lens in the axis of the eye (it is assessed by drawing a perpendicular line on the centre of the cornea) and marked dislocation of Pi3 in the direction of decentration of the planoconvex lens with the convexity facing the cornea.