(n.) A bluish black, amorphous substance containing iron and obtained from blood. It exists the red blood corpuscles united with globulin, and the form of hemoglobin or oxyhemoglobin gives to the blood its red color.
Example Sentences:
(1) The renal failure is thought to have resulted from the presence of circulating free hematin, formed as a result of rapid administration of such a relatively large amount.
(2) The dissociation constants KD, for ligands such as bilirubin, indocyanine green, and hematin were determined by measuring the decrease in the intrinsic fluorescence of the proteins attendant on the addition of ligand.
(3) Severe crisis were successfully treated with Hematin.
(4) In addition, further activation of the hematin-catalase response by NaN3 was depressed in the ischemic side of the hippocampus and striatum.
(5) The chemical nature, etiology and clinical features of hematin calculi are discussed.
(6) HTM incorporates Mueller-Hinton medium with additions of 15 micrograms of hematin per ml, 15 micrograms of NAD per ml, and 5 mg of yeast extract per ml as growth-promoting additives.
(7) We have also shown, through the use of these peroxidase assays and by enzyme absorption spectra, that the peroxidase activity attributed to catalase maintained at alkaline pH is a catalytic but not enzymatic activity associated with a hematin group attached to a denatured catalase monomer.
(8) We have demonstrated that the nitroxyl free radical form of the carcinogen N-hydroxy-2-acetylaminofluorene (OH-AAF) is an obligatory intermediate in the cumene hydroperoxide-hematin-induced oxidative activation of this carcinogen into 2-nitrosofluorene and N-acetoxy-2-acetylaminofluorene.
(9) However, its plasma disappearance curve was not appreciably affected by administration of hematin.
(10) A method was developed for making viable counts of Campylobacter fetus (Vibrio fetus) in tube cultures using a medium containing alkaline hematin and incubation in a carbon dioxide incubator.
(11) Heme oxygenase appeared to be the HO-1 form, an assignment based on its amino acid sequence matching the sequence of 2 peptides obtained from purified HO-1 and the immunochemical properties of the cobalt-, hematin-, and bromobenzene-induced rat liver enzyme.
(12) A statistically significant (p.001) improvement of the level of knowledge of drug prices with increasing experience was found: ampicillin, hematinics, and cough syrup prices were better known than the prices of infrequently prescribed drugs (valproic acid, MMR vaccine).
(13) Hematin binding was noncompetitive with transferase activity and did not involve the bilirubin-binding site, suggesting the existence of unique heme-binding sites on these proteins.
(14) After 2 days of hematin administration, about 5 days were required for delta-aminolevulinic acid, and 11 days for porphobilinogen to return to the concentrations that were detected before treatment.
(15) The major hydrocarbon gas products in iron, copper, or hematin catalyzed peroxidation systems were ethane or ethylene from linolenic acid, and pentane from linoleic acid and arachidonic acid.
(16) There were no statistically significant changes in electrolyte concentrations neither in preterm or prolonged pregnancy, nor in acute or chronic fetal asphyxia, in meconial and hematinic mexures samples as well as in oxytocin infusions with a medium of saline.
(17) Rickettsia quintana grew in a liquid medium consisting of a brain-heart infusion base supplemented with starch and hematin.
(18) The peroxyl radical systems employed are microsomal prostaglandin H synthase and arachidonic acid, the hematin-catalyzed decomposition of a lipid hydroperoxide, and the autoxidation of the sulfite anion.
(19) Fifty-five women with a convincing clinical history of menorrhagia associated with recognizable pelvic disease (40 women) or a confirmed coagulation disorder (15 women) were studied through one or more cycles with measurements of menstrual blood loss volume by a modified alkaline hematin method.
(20) It was shown that hematin was responsible for this P type 204 activity and that it was produced only by actively proteolytic strains when grown on a hemoglobin-containing medium.
Iron
Definition:
(n.) The most common and most useful metallic element, being of almost universal occurrence, usually in the form of an oxide (as hematite, magnetite, etc.), or a hydrous oxide (as limonite, turgite, etc.). It is reduced on an enormous scale in three principal forms; viz., cast iron, steel, and wrought iron. Iron usually appears dark brown, from oxidation or impurity, but when pure, or on a fresh surface, is a gray or white metal. It is easily oxidized (rusted) by moisture, and is attacked by many corrosive agents. Symbol Fe (Latin Ferrum). Atomic weight 55.9. Specific gravity, pure iron, 7.86; cast iron, 7.1. In magnetic properties, it is superior to all other substances.
(n.) An instrument or utensil made of iron; -- chiefly in composition; as, a flatiron, a smoothing iron, etc.
(n.) Fetters; chains; handcuffs; manacles.
(n.) Strength; power; firmness; inflexibility; as, to rule with a rod of iron.
(n.) Of, or made of iron; consisting of iron; as, an iron bar, dust.
(n.) Resembling iron in color; as, iron blackness.
(n.) Like iron in hardness, strength, impenetrability, power of endurance, insensibility, etc.;
(n.) Rude; hard; harsh; severe.
(n.) Firm; robust; enduring; as, an iron constitution.
(n.) Inflexible; unrelenting; as, an iron will.
(n.) Not to be broken; holding or binding fast; tenacious.
(v. t.) To smooth with an instrument of iron; especially, to smooth, as cloth, with a heated flatiron; -- sometimes used with out.
(v. t.) To shackle with irons; to fetter or handcuff.
(v. t.) To furnish or arm with iron; as, to iron a wagon.
Example Sentences:
(1) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
(3) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(4) The specific activities of extracts from cells grown under phototrophic and aerobic conditions were similar and not affected by the concentration of iron in the growth media.
(5) In the 153 women to whom iron supplements were given during pregnancy, the initial fall in haemoglobin concentration was less, was arrested by 28 weeks gestation and then rose to a level equivalent to the booking level.
(6) Typically the iron-iron axis (gz) of the binuclear iron-sulfur clusters is in the membrane plane.
(7) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(8) Lead levels in contents and shells of eggs laid by hens dosed with all-lead shot were about twice those in eggs laid by hens dosed with lead-iron shot.
(9) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(10) Since iron from fortified formulas is well absorbed during the first three months of life, even if it is not immediately used for hemoglobin formation, an inccrease in the iron stores will occur...
(11) Dietary intakes, measured by three 24-hour recalls, revealed that protein, iron and Vitamin C generally met or exceeded the Nutrition Recommendations for age.
(12) This is a struggle for the survival of our nation.” As ever, after Trump’s media dressing-down, his operation was quick to fit a velvet glove to an iron fist.
(13) Ten weeks of iron therapy was not, however, long enough to increase iron stores.
(14) With both approaches, carbohydrate and fat had little influence whereas egg albumin had a significant inhibitory effect on the absorption of nonheme iron.
(15) The protein quality and iron bioavailability of mechanically deboned turkey meat (MDT) and hand-deboned turkey meat (HDT) were determined in rats.
(16) Serum levels of vitamins A and E, zinc and iron were determined in healthy control subjects and lepromatous leprosy patients belonging to an eastern state of India.
(17) Ferric iron in aqueous solution was used as an iron-only control.
(18) The implications of inhibition of protein kinase C by adriamycin-iron(III) are discussed.
(19) The duodenal mucosa of genotypically normal iron replete and iron deficient mice and mice with sex-linked (sla) and microcytic anemias (mk) was examined for the presence of iron-binding proteins.
(20) Ferredoxin reductase (Fd-reductase) supplies reducing equivalents obtained from NADPH to mitochondrial cytochrome P450 enzymes via the small iron-sulfur protein ferredoxin.