(1) Positive HEP values were obtained in 40 patients out of 42 with malignant tumours and in 5 patients out of 12 with other kidney diseases.
(2) Extracts were also prepared from vaccinia-infected HEp-2, RK and W-K cells respectively.
(3) One peptide, designated Hep III, which is thirteen amino acids in length and binds heparin, was active in directly promoting keratinocyte adhesion.
(4) An association between diarrhoea and high level adhesion was observed in that 12 of the 34 faecal isolates and none of the 29 environmental isolates yielded greater than 20 bacteria per HEp-2 cell in the adhesion assay.
(5) The secretion kinetics of nine proteins by Hep G2 cells in culture was investigated using pulse-chase techniques and immunoisolation of proteins with monospecific antibodies.
(6) This finding appeared to be due to Hep G2 cells expressing lipase activities which led to triacylglycerol and phospholipid hydrolysis and lipid reuptake.
(7) DT diaphorase, purified to homogeneity from human Hep G2 cells, did metabolize CB 1954 to this 4-hydroxylamino product, but the rate of CB 1954 reduction and thus production of the cytotoxic product, was much lower than that of purified Walker enzyme (ratio of Kcat = 6.4).
(8) By electron microscopy, E2348 was seen to adhere to HEp-2 cells in a manner that closely resembled EPEC adhesion to intestinal mucosa; bacteria were intimately attached to projections of the apical HEp-2 cell membrane and caused localized destruction of microvilli.
(9) These examinations showed that only the freshly isolated strain of Aa was found within the HEp-2 cells.
(10) B-PEO-HEP coated grafts still showed patency after 3 days.
(11) For poliovirus types 2 and 3 the observed differences in titres were highly significant (p = 0.001) between Hep 2C and Vero cells, Hep 2C and MRC-5 and also between Vero and MRC-5 cells, with higher titres on Hep 2C cells.
(12) R325-beta TK+, a herpes simplex virus 1 mutant carrying a 500-base-pair deletion in the alpha 22 gene and the wild-type (beta) thymidine kinase (TK) gene, was previously shown to grow efficiently in HEp-2 and Vero cell lines.
(13) Methods are described that are used for the titration of antinuclear, anticentromere, and anti-Scl-70 antibodies in systemic scleroderma, systemic lupus erythematosus, and rheumatoid arthritis: indirect immunofluorescence with various antigenic substrates (sections of fresh-frozen rat liver and Hep-2 cell culture), counter-current immunoelectrophoresis, isolation of Scl-70 antigen.
(14) The O157:H8 strains did not produce VT. All gave localised attachment to HEp-2 cells, associated with a positive fluorescence-actin staining test, and all hybridised with the E coli attaching and effacing (eae) probe.
(15) Hep G2 cells produce surplus A alpha and gamma fibrinogen chains.
(16) Adhesion may be studied in vitro systems using HeLa or HEp-2 cells, to which EPEC adhere in a localized pattern.
(17) The serum inhibitory effect appears limited to primary cells because no difference in Ad41 replication, as assayed by accumulation of Ad41 DNA, was found in infected continuous cell lines (HEp-2, 293) cultivated p.i.
(18) Additionally, the invasiveness of C. jejuni M96, a clinical isolate, was significantly increased for HEp-2 cells preinfected with coxsackievirus B3.
(19) Hep 5 impeded binding and degradation of 125I-labelled bovine LPL by perfused rat livers.
(20) To evaluate this possibility, three human cell lines, Hep G2, Hep 3B, and HA 22T, all thought to be arrested in different stages of differentiation based on their biochemical and morphological characteristics, were used as models.
Lep
Definition:
(obs. strong imp.) of Leap. Leaped.
Example Sentences:
(1) Six of the dogs had received Flury strain LEP vaccination.
(2) Further, LEP amplitudes in two patients with bilateral independent temporal lobe seizure onset were markedly diminished compared with one patient with a nontemporal lobe seizure onset.
(3) The most characteristic morphological feature of the CMV-infected BAMB cells was the formation of multinucleated giant cells which frequently contained more than a hundred nuclei; such cells were not seen in LEP cultures.
(4) The results suggest that LEPs are under cholinergic modulation.
(5) While in LEP cells most nucleocapsids were enveloped from the inner leaflet of the nuclear membrane, in the other system a great majority of the particles acquired their envelopes by budding into vacuoles.
(6) Both strains of diploide cells WI 38 and LEP and primary cultures of chicken fibroblast from embryos of SPF chickens did not develop any tumors.
(7) This is the biggest single investment in the north of England by a billion miles,” said Barry Dodd, chair of York, North Yorks and East Riding Local Enterprise Partnership (LEP), supporting the proposal at Tuesday’s planning meeting in Whitby.
(8) To date, the consensus of the health care teams which are involved with the LEP is that 45 minutes every two weeks for discussion and planning for a selected long-stay patient has been time well spent.
(9) The plan will see £556m allocated to Local Enterprise Partnerships in the north of England, £542m to the Midlands and east of England, and £683m to LEPs in the south-west, south-east and London.
(10) LEP and SOC cell lines were contaminated with mouse cells.
(11) A female patient with disfiguring lupus erythematosus profundus (LEP) from the age of 13 years was found to have an isolated partial C4 deficiency, with reduced levels of both allotypes, C4A and C4B.
(12) With this system the lep gene of Salmonella typhimurium was cloned and the nucleotide sequence was determined.
(13) But he criticises the current quality of LEPs that replaced the regional development agencies, calling for them to be strengthened saying "they currently do not have the authority or resource to transform their locality".
(14) Adeno 7 T-antigen was detected earlier and in a higher percentage of GMK cells than in the fully permissive LEP cells and its formation was only slightly influenced by the incubation temperature.
(15) Human diploid cells (LEP) infected with herpes simplex virus (HSV) type 1 were extracted by treatment with Nonidet P-40.
(16) The patients receiving Ambroxol showed an increased LEP mean value (T50 = 18.36 min) in comparison with the baseline mean value (T50 = 16.41 min).
(17) Adeno 7 virus replicated well in human diploid (LEP) cells but only to a low degree in green monkey kidney (GMK) cells at 37 degrees C; it did not replicate in either system at 29 degrees C. At 37 degrees C SV 40 virus replicated well in GMK cells but only moderately in LEP cells; at 29 degrees C it did not replicate in either system.
(18) A RNase in all doses used had no effect on cell proliferation, whereas AS RNase exerted inhibitory activity beginning with the dose of 10 microgram, and affected more markedly the LEP cells (a diploid non-malignant cell line) than the malignant heteroploid HeLa cells.
(19) Adonis has decided not to abolish these 39 LEPs but instead significantly reduce their number and revamp their boundaries so they better match travel-to-work areas.
(20) The aim of the present study was to evaluate the effect of Ambroxol on lung epithelial permeability (LEP) in healthy smokers.