(a.) Descended, or capable of descending, from an ancestor to an heir at law; received or passing by inheritance, or that must pass by inheritance; as, an hereditary estate or crown.
(a.) Transmitted, or capable of being transmitted, as a constitutional quality or condition from a parent to a child; as, hereditary pride, bravery, disease.
Example Sentences:
(1) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
(2) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.
(3) No woman is at greater risk for ovarian carcinoma than one who is a member of a hereditary ovarian carcinoma syndrome kindred and whose mother, sister, or daughter has been affected with this disease and with an integrally related hereditary syndrome cancer.
(4) Governmental officials as well as medical scientists in Taiwan have worked hard in recent years to develop and to implement various measures, such as prenatal diagnosis and neonatal screening, to lower the incidence of hereditary diseases and mental retardation in the population.
(5) Gyrate atrophy is a hereditary chorioretinal degenerative disease caused by a deficiency of the mitochondrial enzyme, ornithine aminotransferase (OAT).
(6) Prophylactic treatment with antifibrinolytic agents, epsilon-aminocaproic and tranexamic acid, reduces the incidence and severity of attacks in patients with hereditary angioedema.
(7) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(8) Serum C1 esterase inhibitor was determined in 138 members of 18 italian families with hereditary angioedema by immunochemical and enzymatic assays.
(9) One may speculate whether clinical conditions exist--apart from hereditary retinal dystrophies--in which the retina becomes more sensitive to light from strong artificial or natural sources, which are otherwise innoxious.
(10) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(11) As there is usually little or no congenital evidence of the dominant type, "infantile" or "autosomal dominant" hereditary endothelial dystrophy would be more appropriate names for the dominant variant.
(12) The autonomic centers in the brain-stem and cerebellum were systematically affected in both the sporadic and the hereditary cases.
(13) Important considerations for the obstetrician concerning hereditary antithrombin III deficiency are discussed, including: 1) the need to therapeutically anticoagulate these patients postpartum, 2) the need to consider prophylactic anticoagulation throughout pregnancy especially in patients with a history of thrombosis, 3) the practical aspects of assaying antithrombin III in plasma rather than serum, 4) the normally low antithrombin III levels in normal newborns, and 5) the need to provide prepregnancy counseling, including information about the autosomal dominant inheritance of hereditary antithrombin III deficiency.
(14) Our findings support the importance of a hereditary factor in migraine but not an autosomal dominant inheritance pattern.
(15) The authors report 23 cases of hereditary epidermolysis bullosa (EB).
(16) The preceding companion paper presents a biochemical study of two abnormal protein 4.1 species from individuals with the red blood cell disorder, hereditary elliptocytosis.
(17) This study examined the function in vitro of aganglionic colon musculature in mice with hereditary aganglionosis--a strain of animals used as a model of Hirschsprung's disease.
(18) In unsystematic schizophrenia the chief factors are hereditary, above all in periodic catatonia.
(19) Lungs of day-18 fetal mice with hereditary chondrodysplasia (cho) were examined histologically and biochemically for pulmonary hypoplasia.
(20) This hereditary lipidosis is characterized pathologically by demyelination, loss of axons, and replacement of the white matter of the caudal cerebrum by a glial scar.
Inborn
Definition:
(a.) Born in or with; implanted by nature; innate; as, inborn passions.
Example Sentences:
(1) This is an inborn error of the mitochondrial beta-oxidation of fatty acids.
(2) Fibroblasts cultured from the skin of a patient with metachromatic leukodystrophy have been found to manifest the biochemical defect of this inborn error of metabolism, a deficiency of arylsulfatase A. Diseased cells had less than five per cent of normal arylsulfatase-A activity, while activities of other lysosomal enzymes-including arylsulfatase B, beta-galactosidase, beta-glucuronidase, and beta-N-acetylglucosaminidase-were comparable to those in control cells.
(3) Defects in this enzyme are responsible for one of the most common inborn errors of metabolism in humans.
(4) The current major indications for prenatal diagnosis are Down's syndrome (Trisomy 21), numerous rare inborn errors of metabolism, and neural tube closure defects.
(5) The authors discuss the problem of administration and amount of fluids and electrolytes in neonates after operations of inborn developmental defects and during the postoperative period.
(6) Hurler syndrome, a lethal inborn error of lysosomal metabolism, results from the systemic accumulation of glycosaminoglycan.
(7) Prognosis of this "inborn error of metabolism" is not favorable due to calcium-oxalate depositions in kidney and other organs.
(8) Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is a common inborn error of mitochondrial fatty acid oxidation.
(9) The child was also shown to be a genetic carrier for ornithine transcarbamylase deficiency, an x-linked inborn error of urea cycle metabolism.
(10) These patients appear to have deleterious inborn enzymatic abnormalities of a type originally postulated by Garrod.
(11) The surgery also impaired the corrective movements, especially if their direction was opposite to the inborn unconditioned reaction.
(12) It appears that most patients with well recognized disorders are not being diagnosed, and it is our conviction that there are new, as yet unidentified, inborn errors of metabolism in this population of patients.
(13) Inborn and learned ability to detect mild, nonpainful distension of the sygmoid colon was examined in 22 patients who underwent colonostomy one year or more before the investigation.
(14) And so we consider psoriasis to be an inborn fault in the metabolism of epidermal and other cells, which is only provoked by secondary influences (drugs, allergic reactions, local traumas).
(15) The hypothesis is advanced that both phenomena represent inborn dialectical logical instruments of evolution-like human identity creation and maintenance.
(16) Jack Ashley provided the political language and the inborn fighting skill, but she would labour to help him find the killer facts.
(17) We want to modify the albino definition as a hereditary and congenital inborn error of metabolism related to the pigment cell, and resulting in a systemic disorder that is characterized by anomalies of eyes, and hypopigmentation in most cases or absence of pigment in skin, hair, and eyes, and of which the neuro-anatomical consequences are the most characteristic.
(18) In a 5-year period, 476 consecutive live and inborn neonates weighing less than or equal to 1000 gm were studied.
(19) We believe that it is particularly suitable for the rapid and acute diagnosis of inborn errors of metabolism, especially the organic acidurias, and for acute pediatric clinical care, when rapid monitoring of major metabolic alterations is required in a time scale suitable to influence directly and immediately the therapy of the patients concerned.
(20) Serum levels of 7 alpha-hydroxycholesterol, 7 beta-hydroxycholesterol and 26-hydroxycholesterol were determined in several groups of patients: normals, untreated patients suffering from cerebrotendinous xanthomatosis, patients suffering from cerebrotendinous xanthomatosis and treated with either chenodeoxycholic acid or cholic acid in an effective dose, patients suffering from cerebro-hepato-renal syndrome, patients suffering from hypercholesterolemia and treated with cholestyramine for prolonged periods and one patient presumed to be suffering from an inborn error of metabolism in bile acid synthesis.