What's the difference between heritable and mutation?

Heritable


Definition:

  • (a.) Capable of being inherited or of passing by inheritance; inheritable.
  • (a.) Capable of inheriting or receiving by inheritance.

Example Sentences:

  • (1) Osteogenesis imperfecta is the common term for a heterogeneous group of heritable disorders of connective tissue with lethal and nonlethal forms.
  • (2) This study focuses on the expansion and maturation of the fatty streak in the aorta of Watanabe Heritable Hyperlipemic rabbits and comparably hypercholesterolemic fat-fed rabbits between 2 and 6 months duration of hypercholesterolemia.
  • (3) Our results illustrate, once again, that heritability is not a constant, but depends on the precise characteristics of the population and the time at which it is studied.
  • (4) A significant relationship with heritable fragile sites was found in this study.
  • (5) The heritability of the two traits of walking behavior was remarkably different; the former was estimated to be about 7%, the latter 26%.
  • (6) The heritability for one of the measures of attention deficit was also significant (h2g = 0.76).
  • (7) As in earlier series, estimates of heritability are higher for mothers than fathers.
  • (8) The genetic implications of establishing the diagnosis of this common heritable X-chromosome abnormality and the therapeutic consequences of detecting the depression are emphasized.
  • (9) The data failed to detect significant heritability, and common family environment proved to be a major determinant in the variation of periodontal health.
  • (10) Dermatopathia pigmentosa reticularis is a rare heritable disorder consisting of a triad of cutaneous findings including reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy.
  • (11) However, when spelling ability was investigated, a heritability of 0.53 was obtained, increasing to 0.75 when intelligence was controlled.
  • (12) Milk yield, fat yield, and protein yield had heritabilities of .36, .38, and .25.
  • (13) Moreover, genetics textbooks consistently employ confused or misleading definitions of the concept of heritability that, together with the reporting of discredited data, perpetuate a fundamentally inaccurate understanding of the genetics of intelligence.
  • (14) Refractive error and the ocular refractive components have heritabilities intermediate between zero and one, as complied from several studies, indicating familial resemblance, but also non-genetic variation.
  • (15) Statistically significant interactions effects of line x diet were noted (P less than .01) for AGE, ADG and Index, traits with low to moderate heritabilities (h2).
  • (16) The heritability estimate of 0.6 appears lower than that from studies in European populations.
  • (17) The results were tabulated and expressed specifically by way of the heritability and repeatability coefficients.
  • (18) Heritability estimates were extremely variable among the different herds and methods of measurement but there was evidence of considerable genetic variation, particularly for sweat gland traits.
  • (19) Radiation-induced heritable lesions in murine leukaemic lymphoblasts L5178Y-S affect progesssion of the cells through the G2 phase of the cell cycle.
  • (20) The somatic mutation theory of carcinogenesis has dominated much of cancer research for the past 30 years, encouraging emphasis on exogenous genotoxic agents capable of inducing malignant transformation via heritable damage to DNA.

Mutation


Definition:

  • (n.) Change; alteration, either in form or qualities.

Example Sentences:

  • (1) Neutrons induced a dose-dependent cytotoxicity and mutation frequency in the AL cells.
  • (2) The hprt T-cell cloning assay allows the detection of mutations occurring in vivo in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene of T-lymphocytes.
  • (3) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
  • (4) Mutational mosaicism was used as a developmental model to analyze 1,500 sporadic and 179 familial cases of retinoblastoma from the world literature.
  • (5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
  • (6) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
  • (7) It is concluded that selection against insertional mutations is unlikely to be the major factor involved in the containment of element abundance.
  • (8) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
  • (9) The plasmid pMucAMucB, constructed from the Haemophilus influenzae vector pDM2, and a similar plasmid, constructed from pBR322, increased the survival after UV irradiation of Escherichia coli AB1157 with the umu-36 mutation and also caused UV-induced mutation in the E. coli strain.
  • (10) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
  • (11) The v-erb A oncogene of avian erythroblastosis virus is a mutated and virally transduced copy of a host cell gene encoding a thyroid hormone receptor.
  • (12) Genetical analysis revealed that resistance to trimethoprim resulted from forward mutations at separate loci rather than back mutations of rad 6 or rad 18 alleles.
  • (13) Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagine synthetase, structural mutations of the enzyme, and gene amplification.
  • (14) Mice with mutations in four nonreceptor tyrosine kinase genes, fyn, src, yes, and abl, were used to study the role of these kinases in long-term potentiation (LTP) and in the relation of LTP to spatial learning and memory.
  • (15) The apparent sensitivity of Escherichia coli K12 to mild heat was increased by recA (def), recB and polA, but not by uvrA, uvrB or recF mutations.
  • (16) Tumorigenesis is a multistep process involving mutations of dominantly acting proto-oncogenes and mutations and loss-of-function mutations of tumor suppressor genes.
  • (17) Appropriate mutations in this pre-early gene allowed a productive infection in ColIb+ cells.
  • (18) Technically speaking, this modality of brief psychotherapy is based on the nonuse of transferential interpretations, on impeding the regression od the patient, on facilitating a cognitice-affective development of his conflicts and thus obtain an internal object mutation which allows the transformation of the "past" into true history, and the "present" into vital perspectives.
  • (19) Mutant alleles of rutabaga act in the germ line cells to partially suppress the developmental defects caused by dunce mutations.
  • (20) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.