(n.) An eruption of the skin, taking various names, according to its form, or the part affected; especially, an eruption of vesicles in small distinct clusters, accompanied with itching or tingling, including shingles, ringworm, and the like; -- so called from its tendency to creep or spread from one part of the skin to another.
(2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(3) Other research has indicated that placing gossypol in the vagina does inhibit the effect of herpes simplex virus type 2 infection, however.
(4) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
(5) (E)-5-(2-Bromovinyl)uridine (BVUrd), the riboside counterpart of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVdUrd), effected a dose-dependent inhibition of viral progeny formation and viral DNA synthesis in herpes simplex virus type 1 (HSV-1, strain KOS)-infected human (E6SM) diploid fibroblast cells.
(6) Among the agents triggering such an infection Chlamydia (30.9% of the cases of non-gonorrhoic urethritis), as well as mycoplasma, ureaplasma, anaerobic bacteria and herpes simplex viruses have gained particular significance.
(7) No effective vaccines are yet available for herpes virus infections.
(8) We have characterized previously a model of herpes simplex virus (HSV) infection of rat dorsal root ganglia (DRG) following cutaneous infection.
(9) IgM antibody titres were not elevated in patients with non-genital herpes simplex, but in patients with herpes genitalis IgM antibodies to HSV type 2 increased to 4 times the normal values 2-4 weeks after infection.
(10) It showed that the proportion of patients attending with recurrent herpes had increased from 18% in 1972 to 31% in 1982.
(11) Acyclovir was shown to limit herpes simplex reactivation in a controlled trial to prevent herpes labialis after surgical intervention for trigeminal neuralgia.
(12) The ability of whole-cell extracts from uninfected HeLa cells to recognize the promoter for the herpes simplex virus type 1 late gene encoding the major capsid protein Vp5 was investigated by using both in vitro transcriptional and S1 nuclease protection analysis.
(13) Sixty-five patients with recrudescent orofacial herpes simplex virus (HSV) infections all had circulating HSV-specific antibody measured by ELISA and cell-mediated immunity (CMI) to HSV by in vitro lymphoproliferation.
(14) 11 strain herpes simplex virus infection of HeLa cells in culture on deoxynucleotide metabolism and the level of various enzymes concerned with the biosynthesis of DNA has been investigated.
(15) 59: 142-153), we described the production and use of complement-dependent virus-neutralizing monoclonal antibodies (MAbs) and MAb-resistant (mar) mutants to identify five antigenic sites (I to V) on herpes simplex virus type 1 glycoprotein B (gB).
(16) Acyclovir is commonly used for suppression and treatment of recurrent genital herpes simplex virus and may be indicated for pregnant women with disseminated herpes.
(17) The factors influencing the interaction of herpes simplex virus (HSV) glycoprotein C (gC) with the third component of complement (C3) were investigated in this study.
(18) Herpes simplex virus type 1 was isolated from the cerebrospinal fluid of a patient during the first attack of multiple sclerosis.
(19) herpes virus) whose transforming activity has been demonstrated for several cell types in vitro and is suspected for some human tumors in vivo.
(20) The development of breakthrough recurrences could not be correlated with infection with strains of herpes simplex virus type 2 that were resistant to acyclovir in vitro.
Shingles
Definition:
(n.) A kind of herpes (Herpes zoster) which spreads half way around the body like a girdle, and is usually attended with violent neuralgic pain.
Example Sentences:
(1) Along with asthenia, polyadenopathies, and shingles, it is often an early sign of AIDS.
(2) This outbreak suggests that shingles can be provoked by reexposure to varicella-zoster virus.
(3) A double-blind, placebo-controlled trial of amantadine hydrochloride (Symmetrel) in acute herpes zoster (shingles) was carried out in 100 patients in general practice.
(4) Somatic sensory perception thresholds (warm, cold, hot pain, touch, pinprick, vibration, two-point discrimination), allodynia and skin temperature were assessed in the affected area of 42 patients with unilateral postherpetic neuralgia (PHN) and 20 patients who had had unilateral shingles not followed by PHN (NoPHN), and in the mirror-image area on the other side.
(5) Acyclovir has demonstrated clinical efficacy for chickenpox, shingles (herpes zoster), genital herpes, and other herpes simplex infections.
(6) Unusual presentations of HIV infected persons which have been seen in Africa include serially developing abscesses in pyomyositis, gall bladder diseases, pericarditis or myocarditis, diseases of the Central Nervous System (cryptococcal meningitis, toxoplasmosis, non-specific leuko-encephalitis, atraumatic paraplegia, acute psychosis or chronic deterioration in mental capacity, lymphoma of the brain), prodromal illnesses, swollen lymph nodes, herpes zoster or shingles in young adults, or tumours of the lymphatic system.
(7) Sacral shingles is associated with sensory loss and flaccid detrusor paralysis.
(8) Patients over 50 with simple shingles should be offered topical idoxuridine or intravenous acyclovir to reduce the risk of post-herpetic neuralgia.
(9) The varicella-zoster virus causes chickenpox and shingles.
(10) Vesicles then appear on the skin in the distribution of this nerve, producing the characteristic dermatomal rash of shingles.
(11) Specimens from patients with smallpox, various forms of vaccination complications, varicella, zoster (shingles), and herpes simplex are included in this evaluation.
(12) By comparison, gypsum pellet carriers sustained penetration rates of 37% in shingle-stacked piles and 87% in random-stacked piles.
(13) At Cley, in North Norfolk, a new nature reserve just purchased by the Norfolk Wildlife Trust was flooded, a bird hide had disappeared and holes punched in the shingle sea bank threaten the whole of the marshes.
(14) They say there is particular concern in the Hunstanton area, where some of the shingle bank has been swept away, and there are reports that Mundesley Cliff Vale Road car park has been washed into the sea.
(15) Four polymorphic loci were studied on an extensive shingle beach at Dungeness.
(16) Herpes zoster or shingles is caused by the DNA virus, varicella-zoster virus, and its major morbidity in older patients is postherpetic neuralgia.
(17) The government would also extend free vaccinations for the shingles virus to older Australians aged 70 to 79 on the national immunisation program, she said.
(18) The other causes of facial paralysis in children are very much less common: a frigore or viral, traumatic, occur ring in the course of acute poliomyelitis, shingles or tumours of the middle ear.
(19) Using the polymerase chain reaction, we performed postmortem examinations of trigeminal and thoracic ganglia of 23 subjects 33 to 88 years old who had not recently had chickenpox or shingles to identify the presence of latent varicella-zoster viral DNA.
(20) Herpes zoster (shingles) is a viral infection that results from a reactivation of a dormant varicella zoster virus.