(a.) Deviating from ordinary forms or rules; irregular; anomalous; abnormal.
(n.) A word which is irregular or anomalous either in declension or conjugation, or which deviates from ordinary forms of inflection in words of a like kind; especially, a noun which is irregular in declension.
(n.) Any thing or person deviating from the common rule, or from common forms.
Example Sentences:
(1) The first concerns precursor cells that give rise to lambda-bearing NP-specific antibodies with heteroclitic fine specificity.
(2) The data suggest that the humoral response to different epitopes of a protein antigen during the maturation of the immune response is a stochastic process leading to transient humoral immunodominance, enhancing Ab populations and heterocliticity, depending upon individual characteristics, either in outbred or inbred populations.
(3) The goal of these experiments has been to capitalize on the functionally distinct responses of heteroclitic CTL to cross-reactive Ag to explore the role of Ag in regulating CTL proliferation and lytic function.
(4) It is predicted that a combination of solid-phase competition assay with high epitope density and direct binding assay with low epitope density would result in optimal detection of heteroclitic antibodies and small differences in antibody affinity for cross-reactive antigens.
(5) By contrast, the heteroclitic Abs to eGH developed by hypopituitary patients therapeutically injected with human growth hormone failed to react with any eGH-derived fragment.
(6) m ABs 8 to 14 and 16 to 20 demonstrated heteroclitic behavior, that is, they bound CTT IIIa better than the immunogen CTT III.
(7) One assay method failed to detect heteroclitic activity of 1 antibody which was clearly evident in the other 3 assays.
(8) Moreover, some anti-BP mAbs and anti-Cop 1 mAbs reacted in a heteroclitic manner and favored the cross-reactive antigen over the immunogen.
(9) However, immunization with the heterologous peptide resulted in a response strictly directed to rat CII and the immunogen while immunization with the autologous peptide elicited T cells which reacted in a heteroclitic fashion, with a stronger response to the heterologous peptide than to the autologous peptide, and did respond to rat CII but not to mouse CII.
(10) Polypeptides (Lys-Ser-Glu)n induced cross-reacting or heteroclitic antibodies.
(11) Monoclonal and anti-dinitrophenyl and anti-trinitrophenyl IgE antibodies were used to measure heterocliticity using competitive inhibition assays with homologous and heterologous haptens.
(12) To our knowledge, this is the first description of a T cell clone that is specific for a class I antigen and cross-reacts heteroclitically with a class II antigen.
(13) A number of antibodies showed heteroclitic binding to particular insulin variants.
(14) Med., 146 (1977) 1323-1331), by comparing the encephalitogenic guinea pig sequence to a less potent analog, had also previously observed what now would be termed a heteroclitic phenomenon at the T cell level in Lewis rats.
(15) In this report, we employ a competition assay to confirm that this alloresponse involves a groove-binding peptide, demonstrate that this peptide derives from or depends on fetal calf serum and exploit a panel of antigen-presenting cell lines--each displaying an Ak complex with a different position 69 substitution--to establish that the alloresponse is not just a heteroclitic response to ribonuclease, itself.
(16) The results indicated temporal and individual variations in the titers of each class of Ab as well as the existence of enhancer and heteroclitic Ab.
(17) Products of both genes had an exotic (heteroclitic) fine-specificity.
(18) Although most of the animals showed cross-reacting Ab, two out of 12 mice, chronically injected, developed heteroclitic Ab.
(19) Heterocliticity towards non-human GH was also detected.
(20) Some of the antibodies could be inhibited to a greater degree with the cross-reacting haptens than with the haptens homologous to the immunizing antigen, therefore these antibodies were heteroclitic.
Inflect
Definition:
(v. t.) To turn from a direct line or course; to bend; to incline, to deflect; to curve; to bow.
(v. t.) To vary, as a noun or a verb in its terminations; to decline, as a noun or adjective, or to conjugate, as a verb.
(v. t.) To modulate, as the voice.
Example Sentences:
(1) An initial complex-soma inflection was observed on the rising phase of the action potential of some cells.
(2) When she speaks, it is in a quiet, clear voice that is middle-class but also flat and London-inflected enough to seem almost classless: it is the voice of the modern southern English professional.
(3) We conclude from these six studies that: (a) BN presents a counter-example to the claim that non-fluent patients have particular difficulty with those aspects of morphology which have a syntactic function; (b) BN processes both derived and inflected words by mapping the sensory input onto the entire full-form of a complex word, but the semantic and syntactic content of the stem alone is accessed and integrated into the context.
(4) The Hill plots of all resonances of the imidazole rings, including the 15N resonances, show a small inflection in the pH range 5.8-6.4.
(5) Two of the three inflection points occurring in the voltammograms are invariant with changes in scan rate, pH, CO2, O2, and glucose.
(6) With prose that takes the English language and infuses it with inflections and a history that is uniquely Igbo, discernibly Nigerian and unmistakably African, Achebe's is a realism that ensures the enduring relevance of his fiction.
(7) We measured the pressure-volume curves (PV curves) of the lung simultaneously at three levels in the esophagus below the tracheal bifurcation using the three-short-balloon-catheter system in 11 normal seated men and compared the inflection points (IP's) of three PV curves with the closing volume (CV) on the single-breath nitrogen washout curve.
(8) Stimulation of secretion of preloaded 125I-mannose-N-acetyl-poly-D-lysine by mannose-BSA was more pronounced at lower temperatures with a sharp inflection point at 10 degrees C. These findings suggest that endosomes containing newly internalized mannose-BSA interact with the exocytosis pathway and enhance secretion of 125I-mannose-N-acetyl-poly-D-lysine from lysosomes.
(9) The inflection in plasma epinephrine shifted in an identical manner and occurred simultaneously with that of TLa (r = 0.97) regardless of the testing protocol or training status.
(10) As the Big Dog waltzed through a thicket of policy points, dropping drawl-inflected catchphrases, the teleprompter stuttered.
(11) The contours of the major components of the far-field CMAPs were frequently interrupted by a series of small amplitude negative and positive peaks or inflections.
(12) Surface tension graphs were similar to those of conventional surfactants, showing apparent critical micelle concentrations (cmc) at distinct inflection points.
(13) The absence of an inflection point show that surface EMG does not provide an indication of Tlac.
(14) The clear inflection point at 3 x 10(-6) M (25 degrees C) observed in the surface tension-concentration curve may not represent the CMC for the formation of multimolecular aggregates.
(15) Thermotolerance was identified from the appearance of an inflection in the survival curve or from the loss of heat resistance in the presence of chloramphenicol (CAM) or rifampicin.
(16) The use of the inflection point is discussed thoroughly, concluding that although it does not allow exclusion of the existence of genotypically different subgroups, the limitations of the data do not permit its use to determine the number of heterozygotes and thus the existence of polymorphism.
(17) On the other hand, the number of groups corresponding to the second inflection is slightly increased.
(18) Parameter estimates are obtained from estimates of the size and time at the point of inflection, the size and time at any other arbitrarily selected point, and the maximum size.
(19) The conversational features within the transcript included the interruptions, pauses, overlaps, inflections, and turn shapes as structured by the participants.
(20) Type II is a spike of short duration (mean 2.0 msec) with only an inflection on the falling phase.