What's the difference between heteromerous and type?
Heteromerous
Definition:
(a.) Unrelated in chemical composition, though similar or indentical in certain other respects; as, borax and augite are homoemorphous, but heteromerous.
(a.) With the parts not corresponding in number.
(a.) Having the femoral artery developed as the principal artery of the leg; -- said of certain birds, as the cotingas and pipras.
(a.) Having five tarsal joints in the anterior and middle legs, but only four in the posterior pair, as the blister beetles and oil beetles.
Example Sentences:
(1) p50B is able to form heteromeric kappa B-binding complexes with RelB, as well as with p65 and p50, the two subunits of NF-kappa B. Transient-transfection experiments in embryonal carcinoma cells demonstrate a functional cooperation between p50B and RelB or p65 in transactivation of a reporter plasmid dependent on a kappa B site.
(2) Thus we conclude that both the dioxin and glucocorticoid receptor can form heteromeric complexes which share a common non-ligand-binding component.
(3) Furthermore, substitution of glutamine for arginine in putative transmembrane segment M2 of the GluR2 subunit makes the heteromeric channels permeable to Ca2+.
(4) Tyrosine phosphorylation acts as a switch to induce the binding of SH2 domains, thereby mediating the formation of heteromeric protein complexes at or near the plasma membrane.
(5) non-DNA binding) 9 S heteromeric complex which contains the Mr approximately 90,000 heat shock protein, hsp90.
(6) Mouse lymphoma cells contain a nonactivated glucocorticoid receptor of Mr approximately 330,000 which is heteromeric in nature and is unable to bind to DNA.
(7) (1984) Biochemistry 23, 1392-1398) that sulfhydryl moieties on the receptor are absolutely required for the receptor to bind to DNA, and they show that the sulfhydryl-modifying reagent does not inhibit the temperature-mediated dissociation of the heteromeric receptor complex that accompanies transformation to the DNA-binding state.
(8) On the basis of these findings, we suggest that subtle changes within the proposed multimerization domain can elicit different effects with the individual Rel-related proteins and that a potential role of p65 delta may be to negatively regulate NF-kappa B function through formation of nonfunctional heteromeric complexes.
(9) Upon expression in cultured cells, the new subunits yielded prominent, typical glutamate- and NMDA-activated currents only when they were in heteromeric configurations with NR1.
(10) Taken together, these observations demonstrate that the steroid-binding domain contains the features required for formation of the 9 S heteromeric complex, and they are consistent with the proposal that the steroid-binding domain normally represses receptor function.
(11) Some in vitro synthesized mineralocorticoid receptor assembles into the heteromeric unactivated form; 2.
(12) We conclude that the large forms of wild-type and nti receptors are heteromeric and contain only one hormone-building polypeptide per complex.
(13) We suggest that TCP1 may represent one of a family of molecules in the eukaryotic cytosol involved in protein folding and regulated in part by their heteromeric associations.
(14) The deduced amino acid sequence of the A chain showed a remarkable identity over a length of 90-amino acid residues with a sequence of the Hap3 polypeptide, a component of a heteromeric multisubunit yeast transcription factor.
(15) Thus, as with gamma-aminobutyric acid, glycine, and nicotinic acetylcholine receptors, native kainate-quisqualate-sensitive glutamate receptors form a family of heteromeric proteins.
(16) Adenovirus infection activates the E2F transcription factor, in part through the formation of a heteromeric protein complex involving a 19 kd E4 gene product that then allows cooperative and stable promoter binding.
(17) The aryl hydrocarbon (Ah) receptor undergoes a ligand-dependent transformation to a heteromeric structure which has the ability to bind DNA sequence-specifically with high affinity.
(18) In hybrids expressing human and rodent ALDH3 no heteromeric isozymes were observed.
(19) Although some of these regulatory principles operate in prokaryotes, the combinatorial nature of the transcriptional activation process, the existence of multiprotein families, and the prevalence of heteromeric protein complexes are characteristic of eukaryotic cells and are essential for the extraordinary complexity of gene expression patterns in multicellular organisms.
(20) The binding of integrin to matrix molecules is sensitive to peptides carrying the cell-binding sequence Arg-Gly-Asp and requires heteromeric integrity.
Type
Definition:
(n.) The mark or impression of something; stamp; impressed sign; emblem.
(n.) Form or character impressed; style; semblance.
(n.) A figure or representation of something to come; a token; a sign; a symbol; -- correlative to antitype.
(n.) That which possesses or exemplifies characteristic qualities; the representative.
(n.) A general form or structure common to a number of individuals; hence, the ideal representation of a species, genus, or other group, combining the essential characteristics; an animal or plant possessing or exemplifying the essential characteristics of a species, genus, or other group. Also, a group or division of animals having a certain typical or characteristic structure of body maintained within the group.
(n.) The original object, or class of objects, scene, face, or conception, which becomes the subject of a copy; esp., the design on the face of a medal or a coin.
(n.) A simple compound, used as a mode or pattern to which other compounds are conveniently regarded as being related, and from which they may be actually or theoretically derived.
(n.) A raised letter, figure, accent, or other character, cast in metal or cut in wood, used in printing.
(n.) Such letters or characters, in general, or the whole quantity of them used in printing, spoken of collectively; any number or mass of such letters or characters, however disposed.
(v. t.) To represent by a type, model, or symbol beforehand; to prefigure.
(v. t.) To furnish an expression or copy of; to represent; to typify.
Example Sentences:
(1) From 1982 to 1989, bronchoplasty or segmental bronchoplasty and pulmonary arterioplasty in combination with lobectomy and segmentectomy were performed for 9 patients with central type lung carcinoma.
(2) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(3) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(4) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(5) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(6) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(7) The half-life of 45Ca in the various calcium fractions of both types of bone was 72 hours in both the control and malnourished groups except the calcium complex portion of the long bone of the control group, which was about 100 hours.
(8) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(9) Irrespective of the type of arthropathy, synovial fluid dialysable hydroxyproline levels correlate with urinary hydroxyproline excretion.
(10) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(11) MRK20 reacted with monocytes, but MRK16 did not with any WBC type.
(12) Type 1 changes (decreased signal intensity on T1-weighted spin-echo images and increased signal intensity on T2-weighted images) were identified in 20 patients (4%) and type 2 (increased signal intensity on T1-weighted images and isointense or slightly increased signal intensity on T2-weighted images) in 77 patients (16%).
(13) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(14) These data indicate that RNA faithfully transfers "suppressive" as well as "positive" types of immune responses that have been reported previously for lymphocytes obtained directly from tumour-bearing and tumour-immune animals.
(15) The present study was therefore carried out to specify further which type of adrenoceptor is involved in lithium-induced hyperglycaemia and inhibition of insulin secretion.
(16) It was concluded that the significant factors affecting outcome are tumor cell type and presence or absence or mitoses.
(17) The invaginations were classified into four easily recognized types: regular, chunky, filigree, and ridge (present only in axon hillock regions).
(18) The RNA polymerase activity was tested after the solubilization and chromatographic resolution of the three types of polymerases with exogenous template.
(19) In choosing between various scanning techniques the factors to be considered include availability, cost, the type of equipment, the expertise of the medical and technical staff, and the inherent capabilities of the system.
(20) Phenotypic relationships were examined between final score and 13 type appraisal traits and first lactation milk yield from 2935 Ayrshire, 3154 Brown Swiss, 13,110 Guernsey, 50,422 Jersey, and 924 Milking Shorthorn records.