(1) Fibroblasts from two such TSD patients had Hex A activity comprising 16% of total Hex when measured by thermal fractionation and quantitation with 4-methylumbelliferyl-beta-D-N-acetylglucosamine (4MUG).
(2) We have shown previously that a mutant sequence (hex-3), which differs from hex-1 by three base pairs, can no longer bind these two factors significantly.
(3) About 200 urine samples, from the various categories listed above, were analyzed for Hex A with both the heat denaturation and pH inactivation methods and the results compared with serum and leukocyte levels from many of the same individuals.
(4) Hexosaminidase in extracts from normal kidney and renal carcinoma tissue could be separated into two major forms [hexosaminidase A (Hex A) and hexosaminidase B (Hex B)] by Cellogel electrophoresis or by diethylaminoethyl cellulose column chromatography.
(5) This finding also suggests that the Hex, Mut, and PMS systems evolved from a common ancestor and that functionally similar mismatch repair systems could be widespread among procaryotic as well as eucaryotic organisms.
(6) The greatest amount of hex S activity was found in fibroblast, but it was also observed in lesser amounts in liver, kidney, intestine and placenta.
(7) At low pH, two of the latter mabs reacted only with Hex B, and it was, therefore, possible to develop enzyme immunoassays for the specific determination of Hex A and Hex B.
(8) The competitive ganglionic nicotinic blocking agent, HEX, on the other hand, inhibited both the increased locomotion produced by CRF in the home cage and also the decreased locomotion induced by CRF in the modified open field.
(9) Hex 70-Inv and Hex 532-Inv, like endogenous lysosomal enzymes, were subject to developmentally induced secretion.
(10) A hexose (Hex)2-3 branch is attached to the heptose linked directly to KDO and a GalNAc-Hex3, GlcNAc, and PEA are separately attached to the second heptose.
(11) The commonly used screening test for detection of Tay-Sachs disease (TSD) carriers is the serum Hex heat inactivation method (HIM), which is based on the assumption that Hex A is the only thermolabile component of Hex; However, in the presence of thermolabile Hex B, HIM could lead to false-negative results.
(12) HEX(C) is shown to differ from HEX(A) and HEX(B) in substrate specificity, molecular size and affinity for Concanavalin-A.
(13) The activities of beta-hexosaminidase (HEX), a lysosomal glycosidase, were studied in serum (sHEX) and urine (uHEX) among men with various drinking habits.
(14) The Hex treated dogs and cats exhibited a fall of MAP and CBF with enhancement of CVR.
(15) The electrophoretic pattern of human fibroblast extracts displays three bands (cathode to anode) of hexosaminidase: Hex B, Hex A, Hex C in normal strains, only one B band in Tay-Sachs strains, and only one C band in Sandhoff strains.
(16) Though monkey tissues also cross-reacted with human seminal plasma Hex-antisera, mouse, rat, and goat testis and epididymis extracts failed to show any cross-reaction.
(17) Hex S, the major residual beta hexosaminidase activity present in tissues, fluids, and cultured skin fibroblasts of patients with type 0 GM2 gangliosidosis, was isolated and characterized biochemically and immunologically.
(18) The persistence of a second major hexosaminidase isozyme, HEX B, does not protect against the lethal accumulation of GM2 ganglioside in the central nervous system.
(19) The results suggest that, in the patient's fibroblasts, a defect in beta-chain synthesis or processing precludes the self-association of beta-chains to form Hex B, but does not prevent the association of alpha- and beta-chains to form Hex A.
(20) Track listing: What Goes Boom Greens and Blues Indie Cindy Bagboy Magdalena 318 Silver Snail Blue Eyed Hexe Ring the Bell Another Toe in the Ocean Andro Queen Snakes Jaime Bravo Track listing for Live in the USA (feat Lenchantin on bass): Bone Machine Hey Ana Magdalena 318 Snakes Indie Cindy I’ve Been Tired Head On The Sad Punk Distance Equals Rate Times Time Something Against You Isla de Encanta Planet of Sound Reading this on mobile?
Spell
Definition:
(n.) A spelk, or splinter.
(v. t.) To supply the place of for a time; to take the turn of, at work; to relieve; as, to spell the helmsman.
(n.) The relief of one person by another in any piece of work or watching; also, a turn at work which is carried on by one person or gang relieving another; as, a spell at the pumps; a spell at the masthead.
(n.) The time during which one person or gang works until relieved; hence, any relatively short period of time, whether a few hours, days, or weeks.
(n.) One of two or more persons or gangs who work by spells.
(n.) A gratuitous helping forward of another's work; as, a logging spell.
(n.) A story; a tale.
(n.) A stanza, verse, or phrase supposed to be endowed with magical power; an incantation; hence, any charm.
(v. t.) To tell; to relate; to teach.
(v. t.) To put under the influence of a spell; to affect by a spell; to bewitch; to fascinate; to charm.
(v. t.) To constitute; to measure.
(v. t.) To tell or name in their proper order letters of, as a word; to write or print in order the letters of, esp. the proper letters; to form, as words, by correct orthography.
(v. t.) To discover by characters or marks; to read with difficulty; -- usually with out; as, to spell out the sense of an author; to spell out a verse in the Bible.
(v. i.) To form words with letters, esp. with the proper letters, either orally or in writing.
(v. i.) To study by noting characters; to gain knowledge or learn the meaning of anything, by study.
Example Sentences:
(1) We outline a protocol for presenting the diagnosis of pseudoseizure with the goal of conveying to the patient the importance of knowing the nonepileptic nature of the spells and the need for psychiatric follow-up.
(2) The government did not spell out the need for private holders of bank debt to take any losses – known as haircuts – under its plans but many analysts believe that this position is untenable.
(3) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(4) John Carver witnessed signs of much-needed improvement from the visitors in a purposeful spell either side of the interval but it was not enough to prevent a fifth successive Premier League defeat.
(5) The lesson, spelled out by Oak Creek's mayor, Steve Saffidi, was that it shouldn't have taken a tragedy for Sikhs, or anyone else, to find acceptance.
(6) Likud warned: “Peres will divide Jerusalem.” Arab states feared that his dream of a borderless Middle East spelled Israeli economic colonialism by stealth.
(7) This could spell disaster for small farmers, says Million Belay, co-ordinator of the Alliance for Food Sovereignty in Africa.
(8) In addition to expected differences in spelling and reading, probands obtained significantly (P less than or equal to .01) lower scores than controls on tests of other cognitive abilities.
(9) Despite fulfilling a boyhood wish to play for Milan when he returned to Italy, the striker admitted he erred in taking his career back to Serie A, having had a controversial spell at Internazionale before City recruited him for £17.5m in August 2010.
(10) Yesterday, John McDonnell spelled out the new Labour leadership’s public investment-driven economic alternative to austerity.
(11) Recognition memory was assessed by asking subjects to indicate which words from a longer list were presented during the spelling test.
(12) It was a spell in which the Dutch were in the ascendancy.
(13) When I wrote this week's public manager column pointing out that there are still too few women in senior public sector leadership roles, it didn't occur to me that I would have to spell out the reasons why it might be a good idea to have a few more women in top positions.
(14) Sigurdsson joined Reading as a youngster in 2005, and had loan spells at Crewe and Shrewsbury before breaking into the first team.
(15) Slow speech development occurred frequently in developmental and acquired spelling dysgraphic children.
(16) True, that comment was made early in Guardiola’s spell as Bayern manager and perhaps it was just a way of endearing himself to his new captain, but there is no doubt the former Barcelona manager adores Lahm.
(17) Since ALS occurs mostly in older age groups, this brings up the possibility that aging changes in the brain could play a causative role in the origin of such spells.
(18) A long spell of ultra-low interest rates has not driven a rise in inequality in the UK, the deputy governor of the Bank of England has said, rebuffing criticism that central bank policy had hurt some households.
(19) 3.05pm BST The Russian foreign ministry has again spelled out Sergei Lavrov's objections to threatening Syria with force if it doesn't comply with the chemical weapons agreement.
(20) However, when spelling ability was investigated, a heritability of 0.53 was obtained, increasing to 0.75 when intelligence was controlled.