(1) Sexual differences in detoxication rate of hexenal persist also in old animals.
(2) Hexenal decreases TE blood plasma level and simultaneously increases their erythrocyte concentration.
(3) Light hexenal anesthesia was found not to affect the mean values of hemodynamics and O2 tension in the blood but increased the CO2 tension in arterial blood and decreased the oxyhemoglobin content and pH of the blood in dogs.
(4) Patterns of hemoproteins turnover were studied in microsomal and mitochondrial fractions of liver tissue of guinea pigs with various duration of hexenal sleep; these patterns were calculated by means of modified procedure involving incorporation of 14C-aminolevulinic acid.
(5) Additional experiments dealt with the perceived intensity of pyridine and cis-3-hexen-1-ol over time in the realistic setting of an environmental chamber.
(6) Opposed to this course, the reaction of 1b with 1,1,1,2,2,3,3-heptafluoro-6-(2-thienyl)-4,6-hexanedione (4) fails to lead to ring closure but rather yields 4,4,5,5,6,6,6-heptafluoro-3-(2-methyl-1-thioureido)-1-(2-thienyl)-1-hexen-1,3-diol (5).
(7) The trauma of the cervical spine was simulated under hexenal anesthesia in non in bred albino rats (100-150 g of weight).
(8) This would suggest similarities in the mechanisms of action of the PAs and alkenals, lending support to the proposed role of trans-4-OH-2-hexenal as an important toxic metabolite of the PAs.
(9) The influence of ecgonine, tropine, tropinon, and some of their derivatives, propan, N-methylpyrrholidine, N-methylpiperidine on impulse summation in the central nervous system, conditioned reflex of avoidance, antagonism to hexenal, synergisim to cocaine and also their toxicity (LD50) have been studied under experimental conditions.
(10) The studies of hexenal concentration have demonstrated the absence of negative effect on the newborn delivered by cesarean section.
(11) All the three preparations suppressed the motor activity, decreased the muscle tone and the body temperature, potentiated the action of hexenal, possessed the antispasmodic and hypnotic activity.
(12) For initial anesthesia, sombrevin, kalipsol, hexenal were applied, basal anesthesia was performed with neuroleptic analgetics and combined electric anesthesia.
(13) Detection thresholds for pyridine and cis-3-hexen-1-ol in argon were 106 ppb and 19 ppb, respectively.
(14) The intensity of metabolism of hexenal, amidopyrine, phenacetin, promedol, acetone, hydrocortisone, testosterone and prostaglandin E2 by the isolated microsomes of the liver, kidneys, small intestinal mucosa and lungs was studied polarographically by the rate of oxygen absorption in experiments on 20 male rabbits four days following partial hepatectomy and liver ischemia.
(15) The duration of action and the pharmacological activity of hexenal, phentanyl, meprobamate, corazole and sodium barbital were studied in male rats with acute intestinal ileus (AII) 12, 24, 48 and 72 hours after its reproduction and 24 hours after surgical treatment.
(16) On the other hand, cyclodecene oxide was a substrate of cEH, but no diol formation was detected when cyclopentene, -hexene and -dodecene oxides were incubated with cytosolic enzyme.
(17) cis-3-hexen-1-ol, trans-2-hexenal, cis-3-hexenyl acetate, trans-2-hexen-1-ol and 1-hexanol, were recorded extracellularly.
(18) Soporific effect of hexenal was distinctly increased in the burns, which correlated to the severity of thermic impairment.
(19) Recently our laboratory isolated trans-4-OH-2-hexenal from the hepatic microsomal metabolism of the macrocyclic pyrrolizidine alkaloid (PA) senecionine and demonstrated in vivo that hepatic necrosis occurred following injection into the hepatic portal vein.
(20) Differences in hexenal detoxication rate and its induction with small doses of phenobarbital in mongrel female rats, depending upon the stage of the sex cycle, were investigated.
Hexine
Definition:
(n.) A hydrocarbon, C6H10, of the acetylene series, obtained artificially as a colorless, volatile, pungent liquid; -- called also hexoylene.