(1) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(2) Throughout the hibernation season (October to April), white adipose tissue-saturated FA percentage decreased, monoene percentage remained constant, and diene percentage increased.
(3) The role of cyclic changes of protein synthesis rate in adaptation of cells of hibernating mammals to functioning at various temperatures is discussed.
(4) In this animal, central vasopressin infusion during the winter prevents hibernation.
(5) To clarify the cause of uncoupling of Ca influx through Ca channels and the contractility of the myocardium in hibernating chipmunks, the electromechanical effects of two different internal Ca store inhibitors, caffeine and ryanodine, and a cardiotonic agent, isoprenaline, were investigated in papillary muscles of hibernating animals.
(6) The mechanism(s) regulating the duration of the period of hibernation was considered to be concerned with some aspect of metabolism and probably the same for all three species.
(7) The possible mechanisms in regulation of the respiration rate of mitochondria from liver of hibernating ground squirrels have been investigated.
(8) Does ursodeoxycholic acid (UDC) production protect hibernating species of Ursidae against gallstone disease?
(9) Such responses to equithesin were not observed in the non-hibernating rodent species.
(10) In neurons from other structures (lateral septum, medial preoptic area, hippocampus) in the brain slices of both hibernating and waking ground squirrels, thyrotropin-releasing hormone did not usually affect the level of spontaneous discharges.
(11) Fetal mesencephalic tissue was grafted into the lateral ventricle following pregraft refrigeration in calcium-free magnesium-free buffer at 4 degrees C. Fetal mesencephalic tissue was hibernated for 5, 12, 16, 20, 24, 28, 32 hours (group A, B, C, D, E, F and G, respectively).
(12) We find that during hibernation the marrow cavity of the long bones is filled with lipid deposits interspersed with vascular sinusoids containing mononuclear cells and red blood cells.
(13) Ten milligrams of lyophilized plasma albumin fractions from hibernating ground squirrels, woodchucks, black bears, and polar bears produced similar inhibition, with partial reversal by naloxone.
(14) We studied nutrient absorption across the brush-border membrane in jejunal tissues from active 13-lined ground squirrels and in hibernating squirrels that had not eaten for at least 6 wk.
(15) Plasma ANF of both groups of nonhibernating marmots was significantly higher (P less than 0.01) than that the hibernating group, but there was no difference between nonhibernating males and females.
(16) The CG and associated DB were therefore found to exert antagonistic effects which are responsible for the control of spermatogonial DNA synthesis in hibernating Helix aspersa.
(17) U69593, however, antagonized hibernation induced by HIT in summer active ground squirrels.
(18) Grafted fetal mesencephalic tissue which had been hibernated for 16 hours or less survived well.
(19) Over 60% of the blood CO2 stores accumulated at the beginning of the hibernation bout were released by hyperventilation during the first period, prior to the full development of thermogenesis.
(20) The heart of ground squirrels is covered by a large amount of brown adipose tissue during the whole period of hibernation.
Migration
Definition:
(n.) The act of migrating.
Example Sentences:
(1) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(2) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
(3) Major forms of the CV-1 factors migrate between 20 and 24 kilodaltons, while the COS factors migrate between 20 and 28 kilodaltons.
(4) Hence the major role of the 14-A arm of carboxybiotin is not to permit a large carboxyl migration but, rather to permit carboxybiotin to traverse the gap which occurs at the interface of three subunits and to insinuate itself between the CoA and keto acid sites.
(5) The rate of accumulation was highest late in infection and only the slower migrating form incorporates significant amounts of glucosamine.
(6) From this proliferating layer, precursor cells migrate outwards to reach the developing neostriatum in a sequential fashion according to two gradients of histogenesis.
(7) Transplanted cells divided in vivo and progressively migrated into the host brain from the site of implantation up to distances of about 1 mm.
(8) These results suggest that bPAG is probably synthesized by trophoblast binucleate cells and stored in granules prior to delivery into the maternal circulation after cell migration.
(9) Our findings: (1) both forms, LC1 and LC3, migrate in the two species with rather similar electrophoretic constants (both in terms of pI and Mr); (2) the LC2 forms of rabbit and humans exhibit the same Mr but quite different pI values, the rabbit forms being more acidic; (3) the chain LC2Sb is resolved into two spots in both rabbit and humans.
(10) The duration of electrophoresis was based on the migration of a marker dye for a predetermined distance.
(11) The dmax migrated rapidly toward the surface with increasing field size at 100-cm SSD.
(12) A decrease in neutrophil oxidative metabolism and iodination was observed, but there was no effect on neutrophil random migration or ADCC.
(13) Locally directed cell migration was observed in a group of cells in 1. which were involved in a process of aggregation, the latter being probably related to precocious formation of organ primordia.
(14) However, the variation in samples, even from among individual animals that had survived challenge, was so great that it precludes the use of the macrophage migration technique as a routine standard assay procedure for immunity.
(15) The isoenzyme mobility diminished in both tumour chromatin extracts, and the slow migrating gamma isoenzyme exhibited sensitivity to L-cysteine inhibition.
(16) The OPL first appears as a thin, discontinuous break in the cytoblast layer that is frequently interrupted by the profiles of migrating neuro- and glioblasts.
(17) On the latter, it migrated as a single polypeptide chain with or without reducing agents and had an apparent mol wt of 62,000.
(18) Fifteen apparently normal patients who had been cured of cryptococcosis were found, as a group, to have impaired responsiveness to skin testing with cryptococcin and mumps, minimal leukocyte migration inhibition when stimulated with cryptococcin or C. neoformans, but normal group responses to cryptococcin in Cryptococcus-induced lymphocyte transformation.
(19) Fc gamma RIII immunoprecipitated from a neutrophil lysate migrated from 40 to 76 Kd, whereas Fc gamma RIII immunoprecipitated from serum from the same donor migrated from 40 to 66 Kd.
(20) A greater degree of inhibition of migration was induced by addition of antigen to mononuclear cells from 18- and 24-hour exudate cells in comparison with 6- and 12-hour exudates.