(v. t.) The act of hindering, or the state of being hindered.
(v. t.) That which hinders; an impediment.
Example Sentences:
(1) The increased hindrance to diffusion of the probing molecules caused by the added solutes is considered as good evidence that the probing molecules diffuse by way of pores filled with water.6.
(2) We develop an analogy between the steric hindrance among receptors detecting randomly placed haptens and the temporary locking of a Geiger counter that has detected a radioactive decay.
(3) The relative reactivities of three o-substituted phenols can be explained in terms of steric hindrance which is minimal for a single o-substituent.
(4) The lower affinity of C8-substituted 7-methyl-1,3-dipropylxanthines can be explained quantitatively with steric hindrance, which C8-substituents experience from the 7-methyl group in these conformations.
(5) A comparison of the antioxidant activities of eight 1,4-naphthoquinones indicated that methyl substitution of C-2, lack of steric hindrance at C-3 or C-5, and (in the case of weak acids) a relatively high pKa are favorable structural features associated with strong antioxidant activity.
(6) However, no steric hindrance can be seen between subunits when the subunits in carbonmonoxy Hb are substituted with the corresponding subunits in deoxy Hb.
(7) This suggests that the one-carbon binding site can accomodate two one-carbon groups simultaneously without serious steric hindrance.
(8) Inter-molecular spread of the conformational change among the molecules of PVX protein was demonstrated in DAS-ELISA, when capture mAb inhibited binding of detecting mAb in the absence of steric hindrance.
(9) 46% of the fatal accidents were caused by crashing against hindrances.
(10) Partial hindrance was observed for the third antibody mAb delta 22.
(11) Intraocular horseradish peroxidase (HRP) accumulated in severed optic axons but was transported with no obvious hindrance in spared axons alongside the lesion.
(12) The molecular areas at which the phase transition occurs under the various experimental conditions, together with a parallel analysis of the hydration states and related molecular areas of the DPPC molecules in multilayers, strongly suggest that the steric hindrance associated with the hydration water of the polar head of DPPC molecules in the monolayer is responsible for the drastic decrease in diffusion coefficient in the liquid-condensed phase.
(13) The spondylodiscites were no hindrance for dorsal lordosing osteotomies and can be treated successfully by means of this static correction and the immobilisation.
(14) At the experiments with the isolated rat hearts, prepared by Langendorff, the anti-arrhythmic dose-effects of the water-soluble antioxidant fenozan from the class of steric-hindrance phenols were studied at condition of regional ischemia and reperfusion, as well as its action on the coronary flow.
(15) Taken together, these results suggest that tonin bound to alpha 1-macroglobulin keeps the active site intact and that inhibition of the enzyme activity is due to a steric hindrance.
(16) Because these inhibitors bind preferentially at the extracellular surface of the transporter, their effects must result from a conformational change rather than from steric hindrance.
(17) We propose that incA, in addition to sequestration, can also restrain replication by causing steric hindrance to the origin function.
(18) Vascular hindrance in muscle, but not hindlimb, was less during nerve stimulation in anemia than at normal Hct.
(19) Intense steric hindrance by introducing an enormously bulky group or complete elimination of the 17 beta-hydroxy group rather decreased the anti-androgenic activity.
(20) Their expertise led to this mess, and would be a hindrance, not a help, in cleaning it up.
Hurdle
Definition:
(n.) A movable frame of wattled twigs, osiers, or withes and stakes, or sometimes of iron, used for inclosing land, for folding sheep and cattle, for gates, etc.; also, in fortification, used as revetments, and for other purposes.
(n.) In England, a sled or crate on which criminals were formerly drawn to the place of execution.
(n.) An artificial barrier, variously constructed, over which men or horses leap in a race.
(v. t.) To hedge, cover, make, or inclose with hurdles.
Example Sentences:
(1) Arsenal’s 10 men fall at the first hurdle against Dinamo Zagreb Read more This win, even against such feeble opponents, was celebrated, with the locals chorusing their manager’s name amid a wave of relief given so much of the team’s domestic campaign to date has been dismal.
(2) The idea was to create a simple set of standards that everyone can relate to, a low hurdle that every humanitarian organisation should be able to leap over.” As organisations grow, they can aspire to use more technical standards that more established NGOs might already be working with.
(3) The physician who cares for adolescents has the responsibility of helping parenting teens to find needed support so that they will be able to overcome this significant hurdle.
(4) When I had that keyhole surgery, I thought: ‘Maybe, if I come back, it won’t be to that top level.’ But with the support I have been getting from my coach, family and friends, I think that really motivated me to come back strong.” Kenya is more famed for its distance runners and steeplechasers than its hurdlers, but the country was left celebrating a surprise gold medal in the 400m hurdles when Nicholas Bett powered home from lane nine to smash his personal best to win in 47.79sec.
(5) Cards pile on the runs, and here comes Hurdle to get Burnett, about three batters too late.
(6) However, despite repeated questions from reporters, Earnest did not rule out Obama approving fast-track without TAA if that combination somehow made it through procedural hurdles in the Senate.
(7) The government is thought to believe that a major hurdle in attracting participants was the fact that it was seen as a service for the lowest socioeconomic groups.
(8) Only a handful of opposition MPs have hurdled the obstacles to win election.
(9) While some predicted their team would once again choke at the final hurdle, the chancellor had faith the “system” would be fully endorsed.
(10) Finding the funds to invest in durable and improved sanitation remains a major hurdle.
(11) Her celebrated experiment with a pseudonym as a demonstration of the hurdles facing unknown writers being just one example.
(12) I just thought it was a little beyond me this year.” On those hazy days in London Ennis-Hill had blown away the opposition with a nerveless and spectacularly quick hurdles on the opening morning of competition that left her cruising to victory.
(13) The great hurdle in all space missions is the cost of launch and the weight of fuel.
(14) However, if what happened with Indiegogo is any indication, the project will likely face more legal hurdles in the future.
(15) Carmarthen ham, an air-dried ham similar to serrano, which has been produced to a recipe by five generations of the same Welsh family, is likely to be the next UK food application to clear the regulatory hurdles.
(16) Some people believe that it just works but the reality is that the online buyer-seller relationship can falter at any one of a number of hurdles.
(17) Medical barriers to family planning (FP) are identified as contraindications, eligibility, process hurdles, the provider of contraception, provider bias, and regulation.
(18) Extinction was conducted in the runway, and subsequently the animals were tested for hurdle-jump escape from the frustrating goal box.
(19) Then they let me go in.” It wasn’t a straightforward process, he explains: his first go was on his own, on videotape; having negotiated that hurdle, he read for casting director Ellen Chenoweth; only then did he get to audition – twice – in front of the Coens themselves.
(20) The pension scheme is regarded as a hurdle to a rescue deal.