(v. t.) The act of hindering, or the state of being hindered.
(v. t.) That which hinders; an impediment.
Example Sentences:
(1) The increased hindrance to diffusion of the probing molecules caused by the added solutes is considered as good evidence that the probing molecules diffuse by way of pores filled with water.6.
(2) We develop an analogy between the steric hindrance among receptors detecting randomly placed haptens and the temporary locking of a Geiger counter that has detected a radioactive decay.
(3) The relative reactivities of three o-substituted phenols can be explained in terms of steric hindrance which is minimal for a single o-substituent.
(4) The lower affinity of C8-substituted 7-methyl-1,3-dipropylxanthines can be explained quantitatively with steric hindrance, which C8-substituents experience from the 7-methyl group in these conformations.
(5) A comparison of the antioxidant activities of eight 1,4-naphthoquinones indicated that methyl substitution of C-2, lack of steric hindrance at C-3 or C-5, and (in the case of weak acids) a relatively high pKa are favorable structural features associated with strong antioxidant activity.
(6) However, no steric hindrance can be seen between subunits when the subunits in carbonmonoxy Hb are substituted with the corresponding subunits in deoxy Hb.
(7) This suggests that the one-carbon binding site can accomodate two one-carbon groups simultaneously without serious steric hindrance.
(8) Inter-molecular spread of the conformational change among the molecules of PVX protein was demonstrated in DAS-ELISA, when capture mAb inhibited binding of detecting mAb in the absence of steric hindrance.
(9) 46% of the fatal accidents were caused by crashing against hindrances.
(10) Partial hindrance was observed for the third antibody mAb delta 22.
(11) Intraocular horseradish peroxidase (HRP) accumulated in severed optic axons but was transported with no obvious hindrance in spared axons alongside the lesion.
(12) The molecular areas at which the phase transition occurs under the various experimental conditions, together with a parallel analysis of the hydration states and related molecular areas of the DPPC molecules in multilayers, strongly suggest that the steric hindrance associated with the hydration water of the polar head of DPPC molecules in the monolayer is responsible for the drastic decrease in diffusion coefficient in the liquid-condensed phase.
(13) The spondylodiscites were no hindrance for dorsal lordosing osteotomies and can be treated successfully by means of this static correction and the immobilisation.
(14) At the experiments with the isolated rat hearts, prepared by Langendorff, the anti-arrhythmic dose-effects of the water-soluble antioxidant fenozan from the class of steric-hindrance phenols were studied at condition of regional ischemia and reperfusion, as well as its action on the coronary flow.
(15) Taken together, these results suggest that tonin bound to alpha 1-macroglobulin keeps the active site intact and that inhibition of the enzyme activity is due to a steric hindrance.
(16) Because these inhibitors bind preferentially at the extracellular surface of the transporter, their effects must result from a conformational change rather than from steric hindrance.
(17) We propose that incA, in addition to sequestration, can also restrain replication by causing steric hindrance to the origin function.
(18) Vascular hindrance in muscle, but not hindlimb, was less during nerve stimulation in anemia than at normal Hct.
(19) Intense steric hindrance by introducing an enormously bulky group or complete elimination of the 17 beta-hydroxy group rather decreased the anti-androgenic activity.
(20) Their expertise led to this mess, and would be a hindrance, not a help, in cleaning it up.
Impediment
Definition:
(n.) That which impedes or hinders progress, motion, activity, or effect.
(v. t.) To impede.
Example Sentences:
(1) Impediments to the necessary growth of this subspecialty for the needs of clinical practice and research are outlined and criteria for certification are reviewed.
(2) An understanding of the possible psychologic impediments to weight loss can promote improved therapeutic intervention for the obese patient.
(3) The results suggest that chronic sunlight exposure may be associated with an impediment to normal maturation of human dermal collagen resulting in tenuous amount of HHL.
(4) In order to achieve palatal closure with the least possible impediment to maxillary growth, the two-stage repair seems to be the best procedure in our hands.
(5) Causes of these impediments to maintaining nutritional status are discussed, and suggestions to overcome them are given.
(6) The data are consistent with the hypothesis that there is a sequential increasing impediment of the programmed cascade for downstream heavy chain constant region gene rearrangements.
(7) Lack of reproducibility is a severe impediment of both current conventional and kinetic methods in the prognosis of gliomas.
(8) These organizations can greatly reduce the logistic impediments to evaluating EMS care and initiating improvements.
(9) Changes in the evaluation protocol could preclude existing impediments to provision of information and patient autonomy; however, certain intrapsychic issues must be recognized as ongoing clinical realities to be addressed as the doctrine of informed consent continues to evolve.
(10) This survey shows that the use of nondiagnostic mammography is still less than optimal, and identifies impediments to screening that need to be addressed in cancer control planning efforts.
(11) The most frequently listed impediments included patients' advanced age or fragility, inadequate health insurance, and excess travel distance.
(12) Major issues identified include operational specificity, mislabelling of procedures, relative contributions of components in multi-faceted treatment packages, and impediments to systematic replication.
(13) The clinics of a single university hospital center were observed to determine a practical rationale for and impediments to implementing a medical care evaluation program.
(14) Accurate assessment and effective response is rendered difficult due to underrepresentation or denial by the patient and countertransference impediments to recognition and limit setting by the therapist.
(15) One impediment to such a study is the absence of any identified gene whose transcription is directly dependent on the receptor-hormone complex.
(16) But, according to Ruddick, the state council is a “gerrymander”, with factional leaders creating new “on-paper” branches that meet at most once a year in order to elect a delegate to state council and keep hold of “the numbers” – presenting Liberal reformers with exactly the same structural impediment to change as is faced by Labor.
(17) Conroy said the Minchin protocol was “merely an administrative policy adopted by the Department of Finance” which was “no impediment to a police investigation into Ms Bishop’s conduct”.
(18) A significant impediment in determining the relative contribution of whole blood viscosity to the pathogenesis of cardiovascular and cerebrovascular disease has been the lack of an uncomplicated method to measure whole blood viscosity.
(19) However, the lack of data on the forms of chromium-absorption from foods by the gastro-intestinal tract, and our concomitant inability to obtain an accurate assessment of the daily mobile pool of metabolically active chromium in the human body continues to be an impediment in assessing the overall impact of chromium nutrition.
(20) The results of this study indicated that the use of a nonresorbable hydroxylapatite for grafting resulted in impediment of tooth eruption and distortion of crown development.