(v. t.) The act of hindering, or the state of being hindered.
(v. t.) That which hinders; an impediment.
Example Sentences:
(1) The increased hindrance to diffusion of the probing molecules caused by the added solutes is considered as good evidence that the probing molecules diffuse by way of pores filled with water.6.
(2) We develop an analogy between the steric hindrance among receptors detecting randomly placed haptens and the temporary locking of a Geiger counter that has detected a radioactive decay.
(3) The relative reactivities of three o-substituted phenols can be explained in terms of steric hindrance which is minimal for a single o-substituent.
(4) The lower affinity of C8-substituted 7-methyl-1,3-dipropylxanthines can be explained quantitatively with steric hindrance, which C8-substituents experience from the 7-methyl group in these conformations.
(5) A comparison of the antioxidant activities of eight 1,4-naphthoquinones indicated that methyl substitution of C-2, lack of steric hindrance at C-3 or C-5, and (in the case of weak acids) a relatively high pKa are favorable structural features associated with strong antioxidant activity.
(6) However, no steric hindrance can be seen between subunits when the subunits in carbonmonoxy Hb are substituted with the corresponding subunits in deoxy Hb.
(7) This suggests that the one-carbon binding site can accomodate two one-carbon groups simultaneously without serious steric hindrance.
(8) Inter-molecular spread of the conformational change among the molecules of PVX protein was demonstrated in DAS-ELISA, when capture mAb inhibited binding of detecting mAb in the absence of steric hindrance.
(9) 46% of the fatal accidents were caused by crashing against hindrances.
(10) Partial hindrance was observed for the third antibody mAb delta 22.
(11) Intraocular horseradish peroxidase (HRP) accumulated in severed optic axons but was transported with no obvious hindrance in spared axons alongside the lesion.
(12) The molecular areas at which the phase transition occurs under the various experimental conditions, together with a parallel analysis of the hydration states and related molecular areas of the DPPC molecules in multilayers, strongly suggest that the steric hindrance associated with the hydration water of the polar head of DPPC molecules in the monolayer is responsible for the drastic decrease in diffusion coefficient in the liquid-condensed phase.
(13) The spondylodiscites were no hindrance for dorsal lordosing osteotomies and can be treated successfully by means of this static correction and the immobilisation.
(14) At the experiments with the isolated rat hearts, prepared by Langendorff, the anti-arrhythmic dose-effects of the water-soluble antioxidant fenozan from the class of steric-hindrance phenols were studied at condition of regional ischemia and reperfusion, as well as its action on the coronary flow.
(15) Taken together, these results suggest that tonin bound to alpha 1-macroglobulin keeps the active site intact and that inhibition of the enzyme activity is due to a steric hindrance.
(16) Because these inhibitors bind preferentially at the extracellular surface of the transporter, their effects must result from a conformational change rather than from steric hindrance.
(17) We propose that incA, in addition to sequestration, can also restrain replication by causing steric hindrance to the origin function.
(18) Vascular hindrance in muscle, but not hindlimb, was less during nerve stimulation in anemia than at normal Hct.
(19) Intense steric hindrance by introducing an enormously bulky group or complete elimination of the 17 beta-hydroxy group rather decreased the anti-androgenic activity.
(20) Their expertise led to this mess, and would be a hindrance, not a help, in cleaning it up.
Interference
Definition:
(n.) The act or state of interfering; as, the stoppage of a machine by the interference of some of its parts; a meddlesome interference in the business of others.
(n.) The mutual influence, under certain conditions, of two streams of light, or series of pulsations of sound, or, generally, two waves or vibrations of any kind, producing certain characteristic phenomena, as colored fringes, dark bands, or darkness, in the case of light, silence or increased intensity in sounds; neutralization or superposition of waves generally.
(n.) The act or state of interfering, or of claiming a right to the same invention.
Example Sentences:
(1) Four cytotoxic antibiotics, bikaverin, duclauxine, PSX-1 and vermiculine, were examined with respect to their interference with glycolysis and respiration and their possible ionophoric or cytolytic activity.
(2) A similar interference colour appeared after incubating sections of rat skin with chymase.
(3) With this system, a brain region loaded with fura-2 was illuminated by a rotating disc bearing three different interference filters of 340, 360 and 380 nm at a rate of 600 rpm.
(4) These results indicate that both racemic and L-baclofen inhibit trigeminal transmission in man, probably because they interfere with excitatory transmission through the interneurons of the lateral reticular formation.
(5) An operant delayed-matching task was used to assess the role of proactive interference (PI) effects on short-term memory capacity of rats.
(6) The last time Vince Cable had a seat in the business department, it was during a high noon of industrial action and state interference in the economy.
(7) Electromagnetic interference presented as inhibition and resetting of the demand circuitry of a ventricular-inhibited temporary external pacemaker in a 70-year-old man undergoing surgical implantation of a permanent bipolar pacemaker generator and lead.
(8) We tested the hypothesis that furosemide interferes with energy generation in the cochlea, and determined its effect on CO2 formation from glucose and glyceroaldehyde-3-phosphate dehydrogenase (GAPDH) activity by examining biochemical and histochemical changes in the cochlea, the kidney, and the liver.
(9) Agents that lower total plasma or LDL cholesterol in hypercholesterolaemic patients by interfering with cholesterol reabsorption from the gut (cholestyramine, cholestipol) or reduction of hepatic VLDL release (fibrates) do not appear to interfere with platelet hyperreactivity and do not change platelet-derived thromboxane formation.
(10) Blockade of beta-adrenoceptors interferes with haemodynamic and metabolic adaptations and ion balance during dynamic exercise.
(11) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(12) It is important for this commission to get to the truth of what happened and it's able to carry on without interference and disruption.
(13) Treatment of bacterial cells with inhibitors of gyrase at high concentration leads to relaxation of DNA supercoils, presumably through interference with the supercoiling activity of gyrase.
(14) Although the general guiding principle of pharmacotherapy for anxiety disorders--the lowest effective dose for the shortest possible time--remains, this rule should not interfere with the judicious use of medications as long as the benefits justify it.
(15) 3H-phorbol ester binding experiments reveal that inhibition by BP may be due to its interference with the phorbol ester binding site and consequently diacylglycerol binding.
(16) Both types of interference can be eliminated by selectively precipitating protein with deoxycholate and trichloroacetic acid (A. Bensadoun and D. Weinstein (1976) Anal.
(17) We conclude that cigarette smoking does interfere with the treatment of hypertension in general, and especially with reduction of blood pressure by propranolol in black patients.
(18) Glutathion and ascorbic acid interfere with the test strip method but this error is neglectable because of physiological low concentrations of these substances.
(19) I called it following the Star Trek Non-Interference Directive.
(20) The absence of uniform definitions prevents meaningful intersystem comparisons, prohibits explorations of hypotheses about effective interventions, and interferes with the efforts of quality assurance.