(v. t.) The act of hindering, or the state of being hindered.
(v. t.) That which hinders; an impediment.
Example Sentences:
(1) The increased hindrance to diffusion of the probing molecules caused by the added solutes is considered as good evidence that the probing molecules diffuse by way of pores filled with water.6.
(2) We develop an analogy between the steric hindrance among receptors detecting randomly placed haptens and the temporary locking of a Geiger counter that has detected a radioactive decay.
(3) The relative reactivities of three o-substituted phenols can be explained in terms of steric hindrance which is minimal for a single o-substituent.
(4) The lower affinity of C8-substituted 7-methyl-1,3-dipropylxanthines can be explained quantitatively with steric hindrance, which C8-substituents experience from the 7-methyl group in these conformations.
(5) A comparison of the antioxidant activities of eight 1,4-naphthoquinones indicated that methyl substitution of C-2, lack of steric hindrance at C-3 or C-5, and (in the case of weak acids) a relatively high pKa are favorable structural features associated with strong antioxidant activity.
(6) However, no steric hindrance can be seen between subunits when the subunits in carbonmonoxy Hb are substituted with the corresponding subunits in deoxy Hb.
(7) This suggests that the one-carbon binding site can accomodate two one-carbon groups simultaneously without serious steric hindrance.
(8) Inter-molecular spread of the conformational change among the molecules of PVX protein was demonstrated in DAS-ELISA, when capture mAb inhibited binding of detecting mAb in the absence of steric hindrance.
(9) 46% of the fatal accidents were caused by crashing against hindrances.
(10) Partial hindrance was observed for the third antibody mAb delta 22.
(11) Intraocular horseradish peroxidase (HRP) accumulated in severed optic axons but was transported with no obvious hindrance in spared axons alongside the lesion.
(12) The molecular areas at which the phase transition occurs under the various experimental conditions, together with a parallel analysis of the hydration states and related molecular areas of the DPPC molecules in multilayers, strongly suggest that the steric hindrance associated with the hydration water of the polar head of DPPC molecules in the monolayer is responsible for the drastic decrease in diffusion coefficient in the liquid-condensed phase.
(13) The spondylodiscites were no hindrance for dorsal lordosing osteotomies and can be treated successfully by means of this static correction and the immobilisation.
(14) At the experiments with the isolated rat hearts, prepared by Langendorff, the anti-arrhythmic dose-effects of the water-soluble antioxidant fenozan from the class of steric-hindrance phenols were studied at condition of regional ischemia and reperfusion, as well as its action on the coronary flow.
(15) Taken together, these results suggest that tonin bound to alpha 1-macroglobulin keeps the active site intact and that inhibition of the enzyme activity is due to a steric hindrance.
(16) Because these inhibitors bind preferentially at the extracellular surface of the transporter, their effects must result from a conformational change rather than from steric hindrance.
(17) We propose that incA, in addition to sequestration, can also restrain replication by causing steric hindrance to the origin function.
(18) Vascular hindrance in muscle, but not hindlimb, was less during nerve stimulation in anemia than at normal Hct.
(19) Intense steric hindrance by introducing an enormously bulky group or complete elimination of the 17 beta-hydroxy group rather decreased the anti-androgenic activity.
(20) Their expertise led to this mess, and would be a hindrance, not a help, in cleaning it up.
Let
Definition:
(v. t.) To retard; to hinder; to impede; to oppose.
(n.) A retarding; hindrance; obstacle; impediment; delay; -- common in the phrase without let or hindrance, but elsewhere archaic.
(n.) A stroke in which a ball touches the top of the net in passing over.
(imp. & p. p.) of Let
(v. t.) To leave; to relinquish; to abandon.
(v. t.) To consider; to think; to esteem.
(v. t.) To cause; to make; -- used with the infinitive in the active form but in the passive sense; as, let make, i. e., cause to be made; let bring, i. e., cause to be brought.
(v. t.) To permit; to allow; to suffer; -- either affirmatively, by positive act, or negatively, by neglecting to restrain or prevent.
(v. t.) To allow to be used or occupied for a compensation; to lease; to rent; to hire out; -- often with out; as, to let a farm; to let a house; to let out horses.
(v. t.) To give, grant, or assign, as a work, privilege, or contract; -- often with out; as, to let the building of a bridge; to let out the lathing and the plastering.
(v. i.) To forbear.
(v. i.) To be let or leased; as, the farm lets for $500 a year. See note under Let, v. t.
Example Sentences:
(1) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(2) Since 1987, it has become possible to obtain immature ova from the living animal and to let them mature, fertilize and develop into embryos capable of transplantation outside the body.
(3) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
(4) But both for malaria and Aids we’re seeing the tools that will let us do 95-100% reduction.
(5) • This article was amended on 1 September 2014 because an earlier version described Platinum Property Partners as a buy-to-let mortgage lender.
(6) Data are shown for both mutagenesis and carcinogenesis, indicating that, in this respect, even the smallest average organ absorbed dose can be effective, particularly for high-LET radiation.
(7) The law would let people find out if partners had a history of domestic violence but is likely to face objections from civil liberties groups.
(8) She said that even as she approached the gates, she was debating with the boy’s father whether to let the first-grader enter.
(9) Western diplomats acknowledge that the capture of Qusair is likely to have emboldened President Bashar al-Assad , making him less likely to consider concessions – let alone stepping down.
(10) We are drawing back the curtains to let light into the innermost corridors of power."
(11) I am rooting hard for you.” Ronald Reagan simply told his former vice-president Bush: “Don’t let the turkeys get you down.” By 10.30am Michelle Obama and Melania Trump will join the outgoing and incoming presidents in a presidential limousine to drive to the Capitol.
(12) His arm was being held by Muntari who let go of it as he entered the penalty area.
(13) A rubber cuff was fixed on the metal cylinder and let an opening of 8 cm, simulating the cervix uteri.
(14) It took years of prep work to make this sort of Übermensch thing socially acceptable, let alone hot – lots of “legalize it!” and “you are economic supermen!” appeals to the balled-and-entitled toddler-fists of the sociopathic libertechian madding crowd to really get mechanized mass-death neo-fascism taken mainstream .
(15) And they have no intention of letting it out of their grasp.
(16) American Horror Story is a paean to the supernatural whose greatest purpose is letting washed-up actors and pop stars chew the scenery on the way to winning awards .
(17) "Getting a 95% loan to value mortgage lets you speculate on the expected house price increases a lot more than a 75% mortgage," he said.
(18) Once installed, the alliance will become an awkward, obstructionist presence, committed, in the words of the Northern League's Matteo Salvini, to "a different Europe, based on work and peoples and not in the one based on servitude to the euro and banks, ready to let us die from immigration and unemployment".
(19) How, in the name of all that is decent and honest in this world did we let this happen?
(20) This was determined by letting the cultured cells phagocytize Latex particles.