What's the difference between histology and safranin?
Histology
Definition:
(n.) That branch of biological science, which treats of the minute (microscopic) structure of animal and vegetable tissues; -- called also histiology.
Example Sentences:
(1) By presenting the case history of a man who successively developed facial and trigeminal neural dysfunction after Mohs chemosurgery of a PCSCC, this paper documents histologically the occurrence of such neural invasion, and illustrates the utility of gadolinium-enhanced magnetic resonance scanning in patient management.
(2) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(3) The angiographic appearances are highly characteristic and equal in value to a histological diagnosis.
(4) By combined histologic and cytologic examinations, the overall diagnostic rate was raised to 87.7%.
(5) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(6) The histological pattern of tumor was identified in 28 cases.
(7) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
(8) Nine months later, the animals were sacrificed, the esophagus and the gastric stump were removed for histologic examination.
(9) It was the purpose of the present study to describe the normal pattern of the growth sites of the nasal septum according to age and sex by histological and microradiographical examination of human autopsy material.
(10) Limited biopsic retroperitoneal lymphnode dissection subsequently extended following the result of the frozen section histology.
(11) Flow cytometric DNA analysis was performed on both fresh and on paraffin embedded samples obtained by gastroscopic biopsies in 5 patients with histologically normal gastric mucosa (20 specimens) and by radical gastrectomies in 9 cases of human gastric cancer (36 specimens).
(12) In 14 of the patients the imaging results were checked against the histological findings of a subsequent thymectomy, which revealed four thymomas and (with the exception of one normal thymus) hyperplastic changes in all the others.
(13) All masses had either histologic confirmation (n = 11) or confirmation with other imaging modalities (n = 4).
(14) The vulvar white keratotic lesions which have been subjected to histological examination in Himeji National Hospital (1973-1987) included 13 cases in benign dermatoses, 4 cases in vulvar epithelial hyperplasia, 3 cases in lichen sclerosus, and 3 cases in lichen sclerosus with foci of epithelial hyperplasia.
(15) The histological examination showed actinomycotic brain absess.
(16) Of 185 with readable histology, 14.6% were clinically and histologically abnormal; 19.5% were clinically abnormal but histologically normal; and 15.7% were clinically normal and histologically abnormal.
(17) The tentative diagnosis "neurinoma of the hypoglossal nerve" was confirmed intraoperatively and histologically.
(18) Histologic examination of the anterior and posterior chambers and the vitreous led to a diagnosis of endophthalmitis caused by Coccidioides immitis infection.
(19) In each case, the roentgenologic diagnosis was confirmed by histological examination.
(20) Histological and electron-microscopic study of the lungs of 15 patients who had been treated with bleomycin for advanced squamous cell carcinoma demonstrated marked histological changes in nine.
Safranin
Definition:
(n.) An orange-red dyestuff extracted from the saffron.
(n.) A red dyestuff extracted from the safflower, and formerly used in dyeing wool, silk, and cotton pink and scarlet; -- called also Spanish red, China lake, and carthamin.
(n.) An orange-red dyestuff prepared from certain nitro compounds of creosol, and used as a substitute for the safflower dye.
Example Sentences:
(1) Stage IV cells contain only safranin-positive granules.
(2) In 13- and 15-day embryos, mast cells showed a pale metachromasia with toluidine blue, and stained blue with Alcian Blue-Safranin O (AB-S).
(3) At 30 and 60 days, an S-100 positive band of cells separated a deep safranin-O positive hypertrophic layer from a fibrocellular surface layer.
(4) The increase of cAMP level also affected the maturation of mast cells, as the ratio of cells of mixed granulation increased, compared to the alcian blue- and safranin-present model inhibited degranulation.
(5) Astra blue (AB) safranine stained highly significantly more mast cells than did toluidine blue.
(6) There was a profound loss of safranin-O stainability in the nucleus pulposus, annulus fibrosus and cartilagenous endplate.
(7) Other staining techniques assessed were the modified Ziehl-Neelsen, safranin-methylene blue and auramine-phenol fluorescence.
(8) A zone of safranin O depletion was present in the ventral anulus fibrosus adjacent to the nucleus pulposus in all treated discs, indicating proteoglycan loss.
(9) The distribution and localization of S-100 protein was compared with safranin-O staining and H and E morphology in relatively unaffected, degenerative, and osteophytic regions of human articular cartilage from 26 joints obtained at the time of total joint replacement for osteoarthritis.
(10) Both safranin O and Giemsa were suitable nonfluorescent staining techniques; lomofungin was not.
(11) After 8-12 weeks, however, many subserosal mast cells became positive for berberine sulfate and safranin.
(12) Defects in treated joints contained Safranin O staining material that was histologically similar to a disorganized hyaline cartilage.
(13) Intestinal MC stained with the same dyes as oral MC except for 0.005% toluidine blue, berberine sulfate, and safranin.
(14) A new microspectrophotometric method was developed for quantitation of glycosaminoglycans with Safranin O dye in articular cartilage matrix.
(15) It is concluded that the use of safranine to monitor the changes in membrane potential during Ca2+ transport by mitochondria should be avoided or special care be taken.
(16) The selectivity of myoepithelial cell staining is enhanced by oxidation of sections, nuclear staining by Safranin-O, and differentiation with Tartrazine.
(17) Ferric ion-ferrocyanide staining and safranin-0-counterstaining of neocortical tissue from cats with GM1 gangliosidosis have established that pyramidal neuron meganeurites occur proximal to axonal initial segments and that they are distinct from axonal spheroids.
(18) Cytochrome oxidase reconstituted vesicles, supplemented with ascorbate and cytochrome c. induce large spectral changes of the positive dye safranine, reversed by uncouplers and inhibitors of respiration.
(19) Histologic specimens of the articular cartilage were stained with Safranin-O to assess proteoglycans-enhanced chrondrocyte function, and the synovium was stained with pentachrome.
(20) Synaptosomes were severely energy-deprived, because anaerobic glycolysis was inhibited by 90% from the aerobic level and mitochondrial membrane potential dropped below the limit that could be detected by the safranine method.