(n.) A tool chiefly for digging up weeds, and arranging the earth about plants in fields and gardens. It is made of a flat blade of iron or steel having an eye or tang by which it is attached to a wooden handle at an acute angle.
(n.) The horned or piked dogfish. See Dogfish.
(v. t.) To cut, dig, scrape, turn, arrange, or clean, with a hoe; as, to hoe the earth in a garden; also, to clear from weeds, or to loosen or arrange the earth about, with a hoe; as, to hoe corn.
(v. i.) To use a hoe; to labor with a hoe.
Example Sentences:
(1) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
(2) The coding region for a secreted proteinaceous inhibitor of the human alpha-amylase (tendamistat; HOE 467) was identified by using a synthetic oligonucleotide probe.
(3) A carcinogenicity study with the LH-RH analog buserelin (HOE 766) was conducted in male and female Wistar rats.
(4) They show HOE 077 to be a promising agent for the inhibition of hepatic fibrosis.
(5) S 0885 and HOE 077 inhibit CCl4-induced liver fibrosis in rats, as shown by significantly reduced hydroxyproline content of the liver and improved liver histology.
(6) A double-blind cross-over study of the effects of HOE 760 (histamine H2-receptor blocker) on diazepam pharmacokinetics was conducted in 12 healthy men.
(7) In addition, the stability of the kinin antagonist, Hoe 140, in synovial fluid was compared with that of synthetic bradykinin.
(8) The addition of increasing concentrations of Hoe 760 to the histamine concentration-response curve caused a parallel rightward shift.
(9) However, the effect of intravenous Hoe 490 was only half as intense as that of HB 419 in the first hours after treatment and the effect of oral Hoe 490 was initially stronger and thereafter temporarily distinctly weaker than that of HB 419.
(10) Studies on absorption and distribution in both skin and organism, as well as on elimination and biotransformation were performed in rats, pigs, and rabbits following topical application of the corticoid prednisolone-17-ethyl carbonate-21-propionate (prednicarbate; test name: Hoe 777), which had been labeled with 14C in position 4 for this purpose.
(11) Mode of action studies were made with Hoe 296, a new synthetic antimycotic, mainly in Candida albicans.
(12) Treatment with ramipril plus the BK B2-receptor antagonist HOE 140 for 6 weeks significantly attenuated the antihypertensive effects of the ACE-inhibitor in 2K1C hypertensive WI rats, but not in 2K1C hypertensive BN-K rats and in SHR.
(13) Partial inhibition by relatively high concentrations of Hoe 296 of the respiratory activity of yeast cells or mitochondria therefrom with exogenous substrates can be explained by decreased uptake of the substrates from the medium.
(14) HOE 077 wa rapidly and completely absorbed after oral administration.
(15) Hoe 065 prevented the disruption of memory induced by scopolamine administered before training.
(16) Preincubation of the detector cells with Hoe 140 completely abolished this nitric oxide release.
(17) The organ distribution of the 125I-labelled (3-9)-heptapeptide fragments was similar to LH-RH, but not to Hoe 766.
(18) The decrease of cardiac activity in Rhesus monkeys amounted to 69% in 24 h, whereas proscillaridin A decreased cardiac activity only by 41% in 24 h. The absorption of HOE 040 from the duodenum of dogs anesthetized with pentobarbital amounted to 72%, whereas proscillaridin A is observed by only between 14 and 25%.
(19) We have developed a neutral human insulin (Hoe 21 GH) which is stabilized for use in implantable roller pumps.
(20) A radioimmunoassay for HOE 766 was developed using 125I[D-Trp6,Des-Gly10]GnRH ethylamide as tracer and an antiserum raised against HOE 766.
Pickaxe
Definition:
(n.) A pick with a point at one end, a transverse edge or blade at the other, and a handle inserted at the middle; a hammer with a flattened end for driving wedges and a pointed end for piercing as it strikes.
Example Sentences:
(1) It has recently been jigsawed together and displayed for only the second time in its history after it was pickaxed from a wall of Keynsham railway station in 1851.
(2) At the bottom of the sandy dunes sit wide turquoise craters, looked over by gritty hills where haphazard tents made from tarpaulins and thatch serve as shelters for the men descending into the hollowed-out pools with pickaxes and buckets.
(3) Mandla Mandela called a press conference in Mvezo village a day after the sheriff of the local court used a pickaxe to force open the gates of his homestead so the bones of Mandela's three late children, including his father, Makgatho Mandela, who died in 2005, could be exhumed.
(4) The vast government compound in Pangkal Pinang is built on a reclaimed mine, and even here men with pickaxes can be seen digging when officials aren't looking.
(5) They are, as the builders of Timbuktu say, “God’s gift to the poor for building.” The only expense involved in collecting the material – which is cut from the ground with pickaxes, rather like peat – is the amount charged by local tip-truck operators and their labourers.
(6) Smoke billowed from vehicles nearby, and men used pickaxes and whatever tools they could find to try to tear down the walls of the mosque.
(7) The Scottish tax adviser said his hands and feet were caned and beaten with a pickaxe handle.
(8) israel jerusalem unrest At one stage the Guardian witnessed a group of masked youths with pickaxes attacking the railway stop.
(9) Under a pounding midday sun, about a dozen men and women watched as an older man plunged a pickaxe into the heavy soil.
(10) Eriu says Amref gave out sanitation kits, which included pickaxes, spades, a wheelbarrow and a hoe.
(11) Angry after being shouted at by Konrad during the exercise, Kenyon responded by plunging a pickaxe into his skull.
(12) If you work slowly, he says, “your characters will take a pickaxe to everything you thought you knew.” Klay’s interest in (and deference to) experiences of the war at odds with his own is very much part of his project.