(1) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
(2) The coding region for a secreted proteinaceous inhibitor of the human alpha-amylase (tendamistat; HOE 467) was identified by using a synthetic oligonucleotide probe.
(3) A carcinogenicity study with the LH-RH analog buserelin (HOE 766) was conducted in male and female Wistar rats.
(4) They show HOE 077 to be a promising agent for the inhibition of hepatic fibrosis.
(5) S 0885 and HOE 077 inhibit CCl4-induced liver fibrosis in rats, as shown by significantly reduced hydroxyproline content of the liver and improved liver histology.
(6) A double-blind cross-over study of the effects of HOE 760 (histamine H2-receptor blocker) on diazepam pharmacokinetics was conducted in 12 healthy men.
(7) In addition, the stability of the kinin antagonist, Hoe 140, in synovial fluid was compared with that of synthetic bradykinin.
(8) The addition of increasing concentrations of Hoe 760 to the histamine concentration-response curve caused a parallel rightward shift.
(9) However, the effect of intravenous Hoe 490 was only half as intense as that of HB 419 in the first hours after treatment and the effect of oral Hoe 490 was initially stronger and thereafter temporarily distinctly weaker than that of HB 419.
(10) Studies on absorption and distribution in both skin and organism, as well as on elimination and biotransformation were performed in rats, pigs, and rabbits following topical application of the corticoid prednisolone-17-ethyl carbonate-21-propionate (prednicarbate; test name: Hoe 777), which had been labeled with 14C in position 4 for this purpose.
(11) Mode of action studies were made with Hoe 296, a new synthetic antimycotic, mainly in Candida albicans.
(12) Treatment with ramipril plus the BK B2-receptor antagonist HOE 140 for 6 weeks significantly attenuated the antihypertensive effects of the ACE-inhibitor in 2K1C hypertensive WI rats, but not in 2K1C hypertensive BN-K rats and in SHR.
(13) Partial inhibition by relatively high concentrations of Hoe 296 of the respiratory activity of yeast cells or mitochondria therefrom with exogenous substrates can be explained by decreased uptake of the substrates from the medium.
(14) HOE 077 wa rapidly and completely absorbed after oral administration.
(15) Hoe 065 prevented the disruption of memory induced by scopolamine administered before training.
(16) Preincubation of the detector cells with Hoe 140 completely abolished this nitric oxide release.
(17) The organ distribution of the 125I-labelled (3-9)-heptapeptide fragments was similar to LH-RH, but not to Hoe 766.
(18) The decrease of cardiac activity in Rhesus monkeys amounted to 69% in 24 h, whereas proscillaridin A decreased cardiac activity only by 41% in 24 h. The absorption of HOE 040 from the duodenum of dogs anesthetized with pentobarbital amounted to 72%, whereas proscillaridin A is observed by only between 14 and 25%.
(19) We have developed a neutral human insulin (Hoe 21 GH) which is stabilized for use in implantable roller pumps.
(20) A radioimmunoassay for HOE 766 was developed using 125I[D-Trp6,Des-Gly10]GnRH ethylamide as tracer and an antiserum raised against HOE 766.
Hoping
Definition:
(p. pr. & vb. n.) of Hope
Example Sentences:
(1) We will never give up our hope for peace,” added Netanyahu.
(2) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(3) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(4) I hope this movement will continue and spread for it has within itself the power to stand up to fascism, be victorious in the face of extremism and say no to oppressive political powers everywhere.” Appearing via videolink from Tehran, and joined by London mayor Sadiq Khan and Palme d’Or winner Mike Leigh, Farhadi said: “We are all citizens of the world and I will endeavour to protect and spread this unity.” The London screening of The Salesman on Sunday evening wasintended to be a show of unity and strength against Trump’s travel ban, which attempted to block arrivals in the US from seven predominantly Muslim countries: Iran, Iraq, Libya, Sudan, Somalia, Syria and Yemen.
(5) Madrid now hopes that a growing clamour for future rescues of Europe's banks to be done directly, without money going via governments, may still allow it to avoid accepting loans that would add to an already fast-growing national debt.
(6) Implications for practice and research include need for support groups with nurses as facilitators, the importance of fostering hope, and need for education of health care professionals.
(7) I’m hopeful but I just can’t get over all my experiences in the past.
(8) I hope I can play a major part in really highlighting the need for far more extensive family violence training within all organisations that deal with women and children, including the police and the department of human services,” Batty said.
(9) HDAra-C in combination with anthracyclines is now considered to be a treatment which may afford some hope of a cure in a certain percentage of cases of adult acute non-lymphocytic leukemia.
(10) Many hope this week's photocalls with the two men will be a recruiting aid and provide a desperately needed bounce in the polls.
(11) I hope they fight for the money to make their jobs worth doing, because it's only with the money (a drop in the ocean though it may be) that they'll be able to do anything.
(12) In a newspaper interview last month, Shapps said the BBC needed to tackle what he said was a culture of secrecy, waste and unbalanced reporting if it hoped to retain the full £3.6bn raised by the licence fee after the current Royal Charter expires in 2016.
(13) He had been just asked to open their new town hall, in the hope he might donate a Shakespeare statue.
(14) Herman Van Rompuy, the European Council president chairing the summit, hoped to finesse an overall agreement on the banking supervisor.
(15) "For a better world, not only for the Iranian people but for the next generation across the globe, I earnestly hope that President Rouhani will receive a warm welcome and meaningful responses during his visit to the UN."
(16) "I hope that he has the sleepless nights I have had for the past five weeks because my son sustained horrific injuries."
(17) Hopes of a breakthrough are slim, though, after WTO members failed to agree a draft deal to rubber-stamp this week.
(18) Another, discussing public attitudes towards the police, said: "I've lost count of [the number of] people who said: 'It's only cos you've got a uniform … if you didn't have the uniform on, I'd come and fuck you and this, that and the other … I hope your wife dies of cancer and your kids die of cancer.'"
(19) They include two leading Republican hopefuls for the presidential race in 2016, Rand Paul and Marco Rubio; three of them enjoy A+ rankings from the NRA and a further eight are listed A. Rand Paul of Kentucky The junior senator's penchant for filibusters became famous during his nearly 13-hour speech against the use unmanned drones, and he is one of three senators who sent an initial missive to Reid , warning him of another verbose round.
(20) A case is presented of deliberate chewing of the flowers of henbane (Hyoscyamus niger) in the hope of producing euphoria, and an account is given of the poisoning so produced.