(1) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
(2) The coding region for a secreted proteinaceous inhibitor of the human alpha-amylase (tendamistat; HOE 467) was identified by using a synthetic oligonucleotide probe.
(3) A carcinogenicity study with the LH-RH analog buserelin (HOE 766) was conducted in male and female Wistar rats.
(4) They show HOE 077 to be a promising agent for the inhibition of hepatic fibrosis.
(5) S 0885 and HOE 077 inhibit CCl4-induced liver fibrosis in rats, as shown by significantly reduced hydroxyproline content of the liver and improved liver histology.
(6) A double-blind cross-over study of the effects of HOE 760 (histamine H2-receptor blocker) on diazepam pharmacokinetics was conducted in 12 healthy men.
(7) In addition, the stability of the kinin antagonist, Hoe 140, in synovial fluid was compared with that of synthetic bradykinin.
(8) The addition of increasing concentrations of Hoe 760 to the histamine concentration-response curve caused a parallel rightward shift.
(9) However, the effect of intravenous Hoe 490 was only half as intense as that of HB 419 in the first hours after treatment and the effect of oral Hoe 490 was initially stronger and thereafter temporarily distinctly weaker than that of HB 419.
(10) Studies on absorption and distribution in both skin and organism, as well as on elimination and biotransformation were performed in rats, pigs, and rabbits following topical application of the corticoid prednisolone-17-ethyl carbonate-21-propionate (prednicarbate; test name: Hoe 777), which had been labeled with 14C in position 4 for this purpose.
(11) Mode of action studies were made with Hoe 296, a new synthetic antimycotic, mainly in Candida albicans.
(12) Treatment with ramipril plus the BK B2-receptor antagonist HOE 140 for 6 weeks significantly attenuated the antihypertensive effects of the ACE-inhibitor in 2K1C hypertensive WI rats, but not in 2K1C hypertensive BN-K rats and in SHR.
(13) Partial inhibition by relatively high concentrations of Hoe 296 of the respiratory activity of yeast cells or mitochondria therefrom with exogenous substrates can be explained by decreased uptake of the substrates from the medium.
(14) HOE 077 wa rapidly and completely absorbed after oral administration.
(15) Hoe 065 prevented the disruption of memory induced by scopolamine administered before training.
(16) Preincubation of the detector cells with Hoe 140 completely abolished this nitric oxide release.
(17) The organ distribution of the 125I-labelled (3-9)-heptapeptide fragments was similar to LH-RH, but not to Hoe 766.
(18) The decrease of cardiac activity in Rhesus monkeys amounted to 69% in 24 h, whereas proscillaridin A decreased cardiac activity only by 41% in 24 h. The absorption of HOE 040 from the duodenum of dogs anesthetized with pentobarbital amounted to 72%, whereas proscillaridin A is observed by only between 14 and 25%.
(19) We have developed a neutral human insulin (Hoe 21 GH) which is stabilized for use in implantable roller pumps.
(20) A radioimmunoassay for HOE 766 was developed using 125I[D-Trp6,Des-Gly10]GnRH ethylamide as tracer and an antiserum raised against HOE 766.
Toeing
Definition:
(p. pr. & vb. n.) of Toe
Example Sentences:
(1) Five cases of mycetoma of bone involving patella, shaft of tibia, medial malleolus, calcaneum and phalanx of great toe are presented.
(2) Doctors, who once treated human body as an entity, are so specialized that none seems to know any more that the head bone is still indirectly connected to the great toe.
(3) "The new feminine ideal is of egg-smooth perfection from hairline to toes," she writes, describing the exquisite agony of having her fingers, arms, back, buttocks and nostrils waxed.
(4) The present study includes six patients, (involving ten feet), who developed hallux varus and great toe clawing after McBride procedures were performed by various orthopedic surgeons.
(5) Impairments of hearing, of mobility, of cutting toe-nails and of general physical activity were the conditions which were most frequently named.
(6) Despite the 2 operations and extensive medical treatment with vasodilators, anticoagulants, and other medication, the pain and limp persisted and a cutaneous necrosis of the 1st and 5th left toes was observed.
(7) We present our results with 8 free transfers of the toe pulp and demonstrate the successful restoration of a well-padded and sensitive fingertip.
(8) Finally, secondary reconstruction techniques are presented, always compared with classical techniques (free 2nd toe transfer versus pollicization).
(9) An equal increase in the number of eroded joints in hands and toes was seen in the penicillamine and the gold group.
(10) Economic analyses were also adjusted for hatchery toe-clipping costs.
(11) The core temperature is taken from the rectum, the nasopharynx or tympanic membrane, and the peripheral temperature from the great toe.
(12) As Cavani was shunted of the ball, it broke to Suarez, who aimed a quick-witted toe-poke at the bottom corner from 15 yards, only to be denied by Buffon, who showed tremendous agility to plunge to his right and tip it around the post!
(13) Computer digitization revealed that distal anastomotic intimal hyperplasia occurred exclusively at the heel and the toe of the graft and the floor of the host artery.
(14) These tests include measurement of the ankle-brachial systolic pressure ratio, a treadmill exercise test, a reactive hyperaemia test, and assessment of toe-pulse reappearance time.
(15) In analogy to tip-toeing movements, it is concluded that the coactivation pattern is typical for stance conditions with a restricted area of support in order to reduce body sway.
(16) The forms of lutein in the toe web were diester (66%0, free alcohol (26%), and monoester (8%) and their sensitivity to aflatoxin followed the same order.
(17) Therefore, the plantar forces acting under the metatarsal heads of the 1st, 2nd and 5th rays and under the pads of the 1st and 2nd toes were measured during walking, so that with the aid of anthropometric information pertaining to the forefoot, reaction forces in the flexor tendons and in the joints could be estimated.
(18) On other days, she dresses head to toe in bright pink.
(19) Both lower limbs were abnormal: the left had a single slender long bone articulating with the foot, which was markedly dorsiflexed and had only 2 toes; on the right the femur was angulated, the fibula was absent, and only 4 metatarsals were present with 4 toes.
(20) The time course of the ionic outflow from the toe web was determined by conductance measurements in the fluid surrounding the web and compared with the visually observed phenomena.