(n.) A hollow place or cavity; an excavation; a pit; an opening in or through a solid body, a fabric, etc.; a perforation; a rent; a fissure.
(n.) An excavation in the ground, made by an animal to live in, or a natural cavity inhabited by an animal; hence, a low, narrow, or dark lodging or place; a mean habitation.
(n.) To cut, dig, or bore a hole or holes in; as, to hole a post for the insertion of rails or bars.
(n.) To drive into a hole, as an animal, or a billiard ball.
(v. i.) To go or get into a hole.
Example Sentences:
(1) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(2) Undaunted by the sickening swell of the ocean and wrapped up against the chilly wind, Straneo, of Woods Hole Oceanographic Institution, one of the world's leading oceanographic research centres, continues to take measurements from the waters as the long Arctic dusk falls.
(3) The speed of visiting holes and the development of a preferred pattern of hole-visits did not influence spatial discrimination performance.
(4) Macular holes, formerly believed to be rare in these injuries, were found in two of the five patients.
(5) Jane's life clearly still has a massive Spike-shaped hole in it.
(6) It would cost their own businesses hundreds of millions of pounds in transaction costs, it would blow a massive hole in their balance of payments, it would leave them having to pick up the entirety of UK debt.
(7) Bar manager Joe Mattheisen, 66, who has worked at the hole-in-the-wall bar since 1997, said the bar has attracted younger, straighter crowds in recent years.
(8) Guzmán was sent to Altiplano high-security prison, 56 miles outside Mexico City, but in July 2015, he absconded again, squeezing through a hole in his shower floor then fleeing on a modified motorbike through a mile-long tunnel fitted with lights and a ventilation system.
(9) If the attacker's plan was to make important ideas disappear down the memory hole, it looks as if it has backfired spectacularly.
(10) In contrast, eyes with macular holes had a greater reduction in the steady-state VEP amplitude than eyes with optic neuritis.
(11) An 8-French right Judkins guiding catheter with a single side hole (USCI), a 3.0 mm balloon dilatation catheter (ACS), and a 0.018 high torque floppy guide wire (ACS) were used.
(12) Four hours p.i., a clustering of the p60 antigen and, 12 h p.i., a formation of finger-like holes, penetrating the nucleus, occurred.
(13) Campbell, Ann E. (Woods Hole Oceanographic Institution, Woods Hole, Mass.
(14) We don't whip homeless vagrants out of town any more, or burn big holes in their ears, as in the brutish 16th century.
(15) The chancellor deliberately made cautious assumptions for the deficit in the budget, but the 5.6% contraction in the economy has blown an even bigger hole in the public finances than feared in April.
(16) He avoided everyone he didn't want to see when he was in Hong Kong, the first place he escaped to, and for several weeks he remained beyond the reach of the world's media, and doubtless a small army of spies, while holed up in a hotel room in the transit area of Moscow's Sheremetyevo airport.
(17) There were no thromboses among infants with long end-hole catheters while infants with short end-hole catheters had thrombosis in 26%, long side-hole catheters in 33% and short side-hole catheters in 64%.
(18) The animal model was induced by left frontal burr hole opening and inoculation of a small piece of G-XII glioma tissue to 6- to 8-week-old rats.
(19) In February last year the BBC was forced to apologise to the Mexican ambassador after a joke made by the three presenters that the nation's cars were like the people "lazy, feckless, flatulent, overweight, leaning against a fence asleep looking at a cactus with a blanket with a hole in the middle on as a coat".
(20) Thus, VP2 and VP5 together form a continuous layer around the inner shell except for holes on the 5-fold axis.
Twitch
Definition:
(v. t.) To pull with a sudden jerk; to pluck with a short, quick motion; to snatch; as, to twitch one by the sleeve; to twitch a thing out of another's hand; to twitch off clusters of grapes.
(n.) The act of twitching; a pull with a jerk; a short, sudden, quick pull; as, a twitch by the sleeve.
(n.) A short, spastic contraction of the fibers or muscles; a simple muscular contraction; as, convulsive twitches; a twitch in the side.
(n.) A stick with a hole in one end through which passes a loop, which can be drawn tightly over the upper lip or an ear of a horse. By twisting the stick the compression is made sufficiently painful to keep the animal quiet during a slight surgical operation.
Example Sentences:
(1) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(2) Twitch-tetanus ratios were calculated and found not to be related to unit contraction time.6.
(3) Hyperosmolar buffer slightly increased the sensitivity and maximal response to methacholine as well as the cholinergic twitch to electric field stimulation.
(4) The present results suggest that TMB-8 blocks twitches by preventing the release of Ca++ ions bound to the intracellular surface of the t-tubular membrane which is often called the store of 'trigger-calcium' ions.
(5) The twitches elicited by 0.1 msec pulses were abolished by tetrodotoxin, but were not reduced by dimethyltubocurarine or by hexamethonium.
(6) Starting from the observation that the part above 6 Hz of the power spectrum of force tremor during isometric contractions can be related to the unfused twitches of motor units firing asynchronously, an attempt was made to study the usefulness of force tremor spectral analysis as a global descriptor of motoneurone pool activity.
(7) The soleus, deep portions of the vastus lateralis, and superficial portions of the vastus lateralis muscles were examined to represent slow-twitch-oxidative, fast-twitch-oxidative-glycolytic, and fast-twitch-glycolytic skeletal muscle fiber types, respectively.
(8) Epinephrine potentiates muscle twitches via the second messenger, cAMP, secondary to hormone binding to membrane-bound beta-receptors.
(9) In physiological studies CDS mimics clonidine's action as an inhibitor of the electrically induced twitch response and as a partial agonist of the epinephrine-induced platelet aggregation.
(10) Facial twitch was followed by the generalized convulsion, further progressing to trembling of the limbs and then kicking of the hindlimb (full seizure) after 55 days of age.
(11) Stimulating the dorsal root at L5 was found to produce hindleg twitches in EAE rats with complete hindlimb paralysis.
(12) The anesthesiologist assessed the degree of neuromuscular blockade intraoperatively prior to pharmacologic reversal either by the standard method of visually counting the number of evoked thumb twitches elicited by supramaximal train-of-four stimulation of the ulnar nerve (i.e., thumb train-of-four count), or by an alternative method such as 1) visually counting the number of evoked orbicularis oculi muscle twitches elicited by supramaximal train-of-four stimulation of the facial nerve, or 2) observing the patient for clinical evidence of partial recovery (e.g., swallowing or attempts to breathe).
(13) Measurements of mouth opening were made for up to 10 min after loss of the adductor pollicis twitch and cessation of muscle fasciculations.
(14) On the other hand, the lack of any twitch-potentiating effect by naloxone methylbromide, a quaternary derivative of naloxone, suggests that opioids which potentiate the twitch must enter the lipid phase of the membrane to act.
(15) The relaxant effect of catecholamines on the twitch is temperature and rate dependent.
(16) Disopyramide 5 X 10(-5) - 10(-3) mol litre-1 produced a concentration-dependent reduction of twitch amplitude in the indirectly stimulated chick biventer cervicis preparation, but greater concentrations were required to reduce twitches elicited directly in the presence of erabutoxin-b 1 microgram ml-1.
(17) The pigeon's metapatagialis muscle consists of three slips, two twitch and one tonic, and these slips are distinguishable at the gross anatomical level.
(18) There was a good correlation between the two methods of measurement for both twitch height and train-of-four ratio (correlation coefficients 0.93 and 0.97, respectively).
(19) Head twitches induced by 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) could be abolished by low doses of RP 62203 in mice (ED50 = 0.44 mg kg-1, p.o.)
(20) Chronic stimulation of the denervated SOL resulted in twitch times-to-peak and half-relaxation times that varied in a graded manner between values longer than those in the normal SOL to values as fast as those in the normal EDL, depending upon the pattern used.