What's the difference between homologous and homology?

Homologous


Definition:

  • (a.) Having the same relative position, proportion, value, or structure.
  • (a.) Corresponding in relative position and proportion.
  • (a.) Having the same relative proportion or value, as the two antecedents or the two consequents of a proportion.
  • (a.) Characterized by homology; belonging to the same type or series; corresponding in composition and properties. See Homology, 3.
  • (a.) Being of the same typical structure; having like relations to a fundamental type to structure; as, those bones in the hand of man and the fore foot of a horse are homologous that correspond in their structural relations, that is, in their relations to the type structure of the fore limb in vertebrates.

Example Sentences:

  • (1) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
  • (2) The ORF2 showed homology with the Escherichia coli regulatory gene ompR, and ORF4 showed homology with E. coli and Rhizobium meliloti regulatory genes fnr and fixK, respectively.
  • (3) Nucleotide sequence analysis of cDNAs for asparagine synthetase (AS) of Pisum sativum has uncovered two distinct AS mRNAs (AS1 and AS2) encoding polypeptides that are highly homologous to the human AS enzyme.
  • (4) In four main regions the conservation varied from 83-91% while in the remaining regions the homology dropped to between 56-62%.
  • (5) It has 61% homology with tRNA(Leu)(anticodon m5CAA) and 63% homology with tRNA(Leu)(anticodon UAG), the two other known yeast tRNAs(Leu).
  • (6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
  • (7) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (8) This unusual insertion could affect the interaction of cat CD4 with class II molecules, or with FIV, a feline homolog of HIV.
  • (9) On the basis of primary sequence homology with other known Pseudomonas lipases, a number of putative active site residues located in conserved areas were found.
  • (10) Extensive sequence homologies and other genetic features are shared with the related oncogenic virus, human papillomavirus type 16, especially in the major reading frames.
  • (11) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
  • (12) Examination of the deduced amino acid sequence revealed an apparent homology to cAMP binding sites in several other proteins.
  • (13) Thus, introduction of arginine in position 5 with a hydrophobic amino acid in position 6 is compatible with high potency in several biological systems and results in compounds with lowered potency to release histamine compared to homologous peptides with tyrosine in position 5 and D-arginine in position 6.
  • (14) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
  • (15) Amino acid analysis indicated a significant number of serine amino acids: N-terminal sequence data demonstrated a high level of homology; and trypsin digestion followed by reversed-phase HPLC indicated the possibility of multiple phosphorylation sites.
  • (16) Homologous insemination in 52 couples during a period of one year yields a conception rate of 38.5%.
  • (17) The region is distinctive in that the sequence is absent from the homologous domain of the erythroid alpha chain and diverges from the normal internal repeat structure observed throughout other spectrins.
  • (18) Surrounding intact ipsilateral structures are more important for the recovery of some of the language functions, such as motor output and phonemic assembly, than homologous contralateral structures.
  • (19) The results show that in both viral DNAs cleavage occurs at the origin and at one additional site which shows striking sequence homology with the origin region.
  • (20) The most striking homology was to yeast SEC7 in the central domain of the gene (57% identical over 466 bp) and also the protein level (42% identical amino acids; 39% conserved amino acids).

Homology


Definition:

  • (n.) The quality of being homologous; correspondence; relation; as, the homologyof similar polygons.
  • (n.) Correspondence or relation in type of structure in contradistinction to similarity of function; as, the relation in structure between the leg and arm of a man; or that between the arm of a man, the fore leg of a horse, the wing of a bird, and the fin of a fish, all these organs being modifications of one type of structure.
  • (n.) The correspondence or resemblance of substances belonging to the same type or series; a similarity of composition varying by a small, regular difference, and usually attended by a regular variation in physical properties; as, there is an homology between methane, CH4, ethane, C2H6, propane, C3H8, etc., all members of the paraffin series. In an extended sense, the term is applied to the relation between chemical elements of the same group; as, chlorine, bromine, and iodine are said to be in homology with each other. Cf. Heterology.

Example Sentences:

  • (1) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
  • (2) The ORF2 showed homology with the Escherichia coli regulatory gene ompR, and ORF4 showed homology with E. coli and Rhizobium meliloti regulatory genes fnr and fixK, respectively.
  • (3) Nucleotide sequence analysis of cDNAs for asparagine synthetase (AS) of Pisum sativum has uncovered two distinct AS mRNAs (AS1 and AS2) encoding polypeptides that are highly homologous to the human AS enzyme.
  • (4) In four main regions the conservation varied from 83-91% while in the remaining regions the homology dropped to between 56-62%.
  • (5) It has 61% homology with tRNA(Leu)(anticodon m5CAA) and 63% homology with tRNA(Leu)(anticodon UAG), the two other known yeast tRNAs(Leu).
  • (6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
  • (7) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (8) This unusual insertion could affect the interaction of cat CD4 with class II molecules, or with FIV, a feline homolog of HIV.
  • (9) On the basis of primary sequence homology with other known Pseudomonas lipases, a number of putative active site residues located in conserved areas were found.
  • (10) Extensive sequence homologies and other genetic features are shared with the related oncogenic virus, human papillomavirus type 16, especially in the major reading frames.
  • (11) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
  • (12) Examination of the deduced amino acid sequence revealed an apparent homology to cAMP binding sites in several other proteins.
  • (13) Thus, introduction of arginine in position 5 with a hydrophobic amino acid in position 6 is compatible with high potency in several biological systems and results in compounds with lowered potency to release histamine compared to homologous peptides with tyrosine in position 5 and D-arginine in position 6.
  • (14) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
  • (15) Amino acid analysis indicated a significant number of serine amino acids: N-terminal sequence data demonstrated a high level of homology; and trypsin digestion followed by reversed-phase HPLC indicated the possibility of multiple phosphorylation sites.
  • (16) Homologous insemination in 52 couples during a period of one year yields a conception rate of 38.5%.
  • (17) The region is distinctive in that the sequence is absent from the homologous domain of the erythroid alpha chain and diverges from the normal internal repeat structure observed throughout other spectrins.
  • (18) Surrounding intact ipsilateral structures are more important for the recovery of some of the language functions, such as motor output and phonemic assembly, than homologous contralateral structures.
  • (19) The results show that in both viral DNAs cleavage occurs at the origin and at one additional site which shows striking sequence homology with the origin region.
  • (20) The most striking homology was to yeast SEC7 in the central domain of the gene (57% identical over 466 bp) and also the protein level (42% identical amino acids; 39% conserved amino acids).