What's the difference between homologous and transvection?
Homologous
Definition:
(a.) Having the same relative position, proportion, value, or structure.
(a.) Corresponding in relative position and proportion.
(a.) Having the same relative proportion or value, as the two antecedents or the two consequents of a proportion.
(a.) Characterized by homology; belonging to the same type or series; corresponding in composition and properties. See Homology, 3.
(a.) Being of the same typical structure; having like relations to a fundamental type to structure; as, those bones in the hand of man and the fore foot of a horse are homologous that correspond in their structural relations, that is, in their relations to the type structure of the fore limb in vertebrates.
Example Sentences:
(1) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
(2) The ORF2 showed homology with the Escherichia coli regulatory gene ompR, and ORF4 showed homology with E. coli and Rhizobium meliloti regulatory genes fnr and fixK, respectively.
(3) Nucleotide sequence analysis of cDNAs for asparagine synthetase (AS) of Pisum sativum has uncovered two distinct AS mRNAs (AS1 and AS2) encoding polypeptides that are highly homologous to the human AS enzyme.
(4) In four main regions the conservation varied from 83-91% while in the remaining regions the homology dropped to between 56-62%.
(5) It has 61% homology with tRNA(Leu)(anticodon m5CAA) and 63% homology with tRNA(Leu)(anticodon UAG), the two other known yeast tRNAs(Leu).
(6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(7) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(8) This unusual insertion could affect the interaction of cat CD4 with class II molecules, or with FIV, a feline homolog of HIV.
(9) On the basis of primary sequence homology with other known Pseudomonas lipases, a number of putative active site residues located in conserved areas were found.
(10) Extensive sequence homologies and other genetic features are shared with the related oncogenic virus, human papillomavirus type 16, especially in the major reading frames.
(11) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
(12) Examination of the deduced amino acid sequence revealed an apparent homology to cAMP binding sites in several other proteins.
(13) Thus, introduction of arginine in position 5 with a hydrophobic amino acid in position 6 is compatible with high potency in several biological systems and results in compounds with lowered potency to release histamine compared to homologous peptides with tyrosine in position 5 and D-arginine in position 6.
(14) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
(15) Amino acid analysis indicated a significant number of serine amino acids: N-terminal sequence data demonstrated a high level of homology; and trypsin digestion followed by reversed-phase HPLC indicated the possibility of multiple phosphorylation sites.
(16) Homologous insemination in 52 couples during a period of one year yields a conception rate of 38.5%.
(17) The region is distinctive in that the sequence is absent from the homologous domain of the erythroid alpha chain and diverges from the normal internal repeat structure observed throughout other spectrins.
(18) Surrounding intact ipsilateral structures are more important for the recovery of some of the language functions, such as motor output and phonemic assembly, than homologous contralateral structures.
(19) The results show that in both viral DNAs cleavage occurs at the origin and at one additional site which shows striking sequence homology with the origin region.
(20) The most striking homology was to yeast SEC7 in the central domain of the gene (57% identical over 466 bp) and also the protein level (42% identical amino acids; 39% conserved amino acids).
Transvection
Definition:
(n.) The act of conveying or carrying over.
Example Sentences:
(1) Chromosomal rearrangements which disrupt transvection possess a breakpoint in a particular segment of the chromosome arm bearing the transvection-sensitive gene (arm 2L for the DDP-C and 3R for the BX-C); this segment of each arm has been termed the critical region by Lewis (1954).
(2) The zeste gene product is required for transvection effects that imply the ability of regulatory elements on one chromosome to affect the expression of the homologous gene in a somatically paired chromosome.
(3) The factor Dichaete (D3) permits easier scoring of the transvection phenotype.
(4) Possible mechanisms for the trans-acting effect of niv-525 and its relationship to other examples of allelic interactions, such as transvection in Drosophila melanogaster, are discussed.
(5) These results indicate that both the zeste-white interaction and transvection effects require the formation of high order aggregates.
(6) We discuss the normal cis regulatory role of these functions involved in trans interactions between homologous Ubx genes, as well as the implications of our results for the current models on transvection.
(7) Only Cbx2 and CbxIRM (a revertant of Cbx1) show synapsis-dependent gene expression ("transvection").
(8) These recent observations continue a history of studies concerning zeste and transvection which has inspired molecular models linking chromosome structure and positioning to the modulation of gene expression.
(9) Somatic transfer of genomic imprinting between homologs by means of a transvection-like process between paired Tme and T loci is proposed as a model to explain the results obtained.
(10) We show that this domain is responsible for the extensive aggregation properties of zeste that are required for its role in transvection phenomena.
(11) A new adaptation of the bithorax transvection method by Mendelson permits the recovery of high yields of chromosome aberrations in a fast one-generation test.
(12) We have confirmed that, although the Ubx1 allele does not produce detectable Ubx proteins (UBX), it does retain other genetic functions detectable by their effects on the expression of a paired, homologous Ubx allele, i.e., by transvection.
(13) The conditions necessary for each transvection effect were determined from these transvection groups.
(14) The genetic properties of the proximity-dependent allelic complementation (termed transvection effects) at the BX-C and DPP-C, are quite similar.
(15) Transvection was explained by trans-activation of promoter in y2-allele by enhancer of y1-allele.
(16) The bithorax34e mutation only transvects with Ultrabithorax mutations with a contiguous Ultrabithorax transcriptional unit.
(17) The zeste gene product is involved in two types of genetic effects dependent on chromosome pairing: transvection and the zeste-white interaction.
(18) Special attention is paid to the transvection effect (synapsis-dependent interaction between white and zeste genes), cis-acting regulatory elements and the behaviour of the white genes introduced into the genome by P element-mediated DNA transformation.
(19) Surprisingly, previous genetic experiments indicate that zeste is a nonessential gene shown only to act in a dispensable regulatory process termed transvection.
(20) One can discriminate between otherwise phenotypically similar mutations via their transvection behavior.