What's the difference between hopeless and vain?

Hopeless


Definition:

  • (a.) Destitute of hope; having no expectation of good; despairing.
  • (a.) Giving no ground of hope; promising nothing desirable; desperate; as, a hopeless cause.
  • (a.) Unhoped for; despaired of.

Example Sentences:

  • (1) Its experiments are so hopelessly flawed that the results are meaningless."
  • (2) They were preceded by the publication of The Success and Failure of Picasso (1965) and Art and Revolution: Ernst Neizvestny and the Role of the Artist in the USSR (1969); in one, he made a hopeless mess of Picasso’s later career, though he was not alone in this; in the other, he elevated a brave dissident artist beyond his talents.
  • (3) Rather than ruthlessly efficient, I have found them sweet and a bit hopeless."
  • (4) Alcohol and drugs are influential in providing a feeling of hopelessness by their toxic effects, by disruption of interpersonal relationships and social supports, and, possibly, by manipulating neurotransmitters responsible for mood and judgment.
  • (5) The authors document the first 19 months of a service dedicated to the care of hopelessly ill patients in a teaching hospital.
  • (6) "); hopeless self-pity ("Nobody said anything to me about Billy ... all day long") and rage ("You want to put a bench in the park in Billy's name?
  • (7) Winston Churchill, when he was offered the role of minister of the local government board in 1906, commented: "There is no place more laborious, more anxious, more thankless, more cloaked with petty and even squalid detail, more full of hopeless and insoluble difficulties."
  • (8) It’s all very well for Hopeless to make fun of me saying Brexit means Brexit,” said Hapless, haplessly.
  • (9) Meanwhile, the dance music that sells in any quantity is just hopeless.
  • (10) Both depression and hopelessness were sensitive to changes in suicide risk during the one-month follow-up.
  • (11) Many aspects of the theory's descriptive claims about depressive thinking have been substantiated empirically, including (a) increased negativity of cognitions about the self, (b) increased hopelessness, (c) specificity of themes of loss to depressive syndromes rather than psychopathology in general, and (d) mood-congruent recall.
  • (12) In addition, the paper presents the author's experience with human vitreous transplantation by the 'open sky' transcorneal technique for otherwise hopeless vitreous opacities.
  • (13) The relationship between depression and suicide disappears when hopelessness is taken into account.
  • (14) The performance of controls and DST escapers was related to depth of semantic processing, whereas performance of DST suppressors varied inversely with degree of felt hopelessness.
  • (15) The question of vulnerability to DSH is discussed as well as the possibility of using measures of hopelessness and intropunitive hostility to identify those at greater risk of repetition.
  • (16) But the Labour leader has only himself to blame because of his hopelessly woolly response to a question on this in his BBC interview on Monday.
  • (17) "It was a certain kind of titillation the shop offered," the critic Matthew Collings has written, "sexual but also hopeless, destructive, foolish, funny, sad."
  • (18) Shinji Kagawa could not make any real difference and Marouane Fellaini continues to look hopelessly out of his depth.
  • (19) Anhedonia, diurnal variation, hopelessness, psychomotor retardation, and delusions increased with age; depressed appearance, low self-esteem, and somatic complaints decreased with age.
  • (20) Four cases received no treatment but were recalled, and twelve perforations showed a size and location hopeless for repair; the teeth were therefore extracted.

Vain


Definition:

  • (superl.) Having no real substance, value, or importance; empty; void; worthless; unsatisfying.
  • (superl.) Destitute of forge or efficacy; effecting no purpose; fruitless; ineffectual; as, vain toil; a vain attempt.
  • (superl.) Proud of petty things, or of trifling attainments; having a high opinion of one's own accomplishments with slight reason; conceited; puffed up; inflated.
  • (superl.) Showy; ostentatious.
  • (n.) Vanity; emptiness; -- now used only in the phrase in vain.

Example Sentences:

  • (1) For example, if we purchase new examination equipment without any consideration or if we decide what type of equipment to introduce according to the common advice of the purchase committee of the hospital or the medical school, then we cannot design an ideal system of laboratory examinations and are forced to invest a large sum of money in vain.
  • (2) The George Bush campaign juggernaut hit the first serious pothole of its cash-fuelled drive to the presidency yesterday, as the Texas governor tried in vain to fend off questions about whether he had used cocaine as a young man.
  • (3) Full set list, show one (thanks to princevault.com ) Take Me With U (acoustic) Raspberry Beret (acoustic) U Got The Look (acoustic) Instrumental jam (acoustic) Train In Vain (acoustic) Q & A (1) incl.
  • (4) VaIN rarely is an isolated lesion and frequently is preceded by, or coexists with, other types of premalignant genital squamous neoplasia.
  • (5) He’s the kind of self-styled intellectual journalist in politics who caused so much trouble in 20th century politics, not a bad man, decent enough in his way, but not as smart as he thinks he is, vain with it.
  • (6) For long spells, West Ham searched in vain for inspiration as they tried to find a way past Newcastle United’s defence and end a run of three matches without a win.
  • (7) Further, in a vain attempt for a boost in the Hoosier State, Cruz unveiled former rival Carly Fiorina as his running mate if he receives the nomination and was able to cajole the state’s sitting governor, Mike Pence, into an endorsement.
  • (8) The next few days may well determine whether, this time, such loyalty will be in vain; but, while yearning for a clarion call and what was described as "vision" in this paper's leading article yesterday, I need to pose some pretty stark questions to Guardian readers.
  • (9) He aims to put his newspapers, including the Times and the Sun, behind a paywall, something described by the co-founder of Twitter, Biz Stone, as a vain attempt to "put the genie back in the bottle".
  • (10) In vain I argued that Robin Day seemed to wear the same jacket and shirt every week, and fled back to radio."
  • (11) Now I can feel that my son's blood wasn't totally lost in vain.
  • (12) In vain will Cameron plead that blame should lie with Brown and his Labour colleagues.
  • (13) At a media day held to mark the completion of the training and arranged before the tragedy, soldier after soldier came forward to insist that, though they were apprehensive, they were determined to do a good job, partly to make sure that their six colleagues had not died in vain.
  • (14) He somehow scrambled to deuce and delighted in forcing Dimitrov to chase in vain from one side of the court to the other to go 6-5 up.
  • (15) Assessment of patients between 9 and 99 (mean 55) months after partial colpectomy for VAIN showed no recurrence of disease in ten patients (83%).
  • (16) The scientific establishment struggled in vain to produce evidence that would reassure the public.
  • (17) No grieving wants to go through that, and our city doesn’t want to go through that.” Murphy said an accelerated program to equip Baltimore police officers with body cameras would mean Gray “did not die in vain”.
  • (18) His mother has said she tried in vain to get help for him.
  • (19) But he flailed in vain as the police officers grabbed him, one forcing his T-shirt roughly up over his head as three or four others laid in with their wooden batons, dragging and pushing him to a line of waiting Land Cruisers and more helmeted cops.
  • (20) As Steve spends half his money trying in vain to keep a scowl off Michelle's face and the rest comfort eating, Liz stumped up half the cash.