(1) In a previous analysis of the Hox-1.1 promoter in transgenic mice, we identified sequences that were sufficient to establish transgene expression in a specific region of the embryo.
(2) Thus, Hox-1.6 is involved in regional specification along the rostrocaudal axis, but only in its most rostral domain of expression.
(3) The mouse Hox 2.1 gene contains a homeobox sequence and is therefore a candidate for a vertebrate gene involved in the control of embryonic patterning or positional specification.
(4) The results show that the Hox 2.1 gene produces at least two related phosphorylated proteins present in different proportions in different tissues.
(5) Two of the hox appear to be cognates of the human Hu-1 (or mouse Hox 2.1) and the mouse Hox 1-3, while another is closely related to the mouse Hox 1-4.
(6) The expression of the eleven HOX 1 genes is lineage-restricted and these genes are predominantly detected within cells of myelomonocytic origin.
(7) Our analysis of Hox 1.3 cDNA and genomic clones indicates that the gene is organized into two exons and encodes a 270-amino-acid homeo domain protein.
(8) Southern blotting shows that the DNA sequence encoding Hox-6.1 is single copy.
(9) A 2.4 kb RNA encoded by the murine Hox 1.1 (m6) homeobox gene is induced when F9 stem cells are differentiated with retinoic acid and dibutyryl cyclic AMP.
(10) This report demonstrates that the genes in the murine Hox-2 cluster display spatially and temporally dynamic patterns of expression in the transverse plane of the developing CNS.
(11) The early transcription pattern thus appears to be compatible with a regionalizing role for the Hox-3.1 gene.
(12) Here we show correct regulation by Hox-1.1 sequences in transgenic mice and identify the elements responsible for different levels of control.
(13) The resulting Hox-2.2 misexpression produces early postnatal lethality as well as craniofacial and axial skeletal perturbations that include open eyes at birth, cleft palate, micrognathia, microtia, skull bone deficiencies, and structural and positional alterations in the vertebral column.
(14) This article reviews recent studies on the expression of the homeobox gene, Hox 2.1, during mouse embryogenesis, using the technique of in situ hybridization.
(15) In situ hybridization shows that Hox 2.1 transcripts are regionally localized in the spinal cord in an apparent anterior-posterior gradient extending from the hind brain.
(16) In this review we have built a case for abnormal Hox gene expression in human congenital malformations without presenting any direct evidence of their involvement.
(17) Hox 2.3 was also super-induced by serum, in the presence of cycloheximide, in cells rested previously in serum-free media, suggesting that new protein synthesis was not required for expressive augmentation.
(18) To further understand their regulation, the genomic loci of four newt HBox genes (two from the human HBox (HOX)-2 complex and two from the HOX-3 complex) were analysed and compared with homologous loci in other vertebrates.
(19) DNase I protection of the Hox-1.3 gene promoter region with the Hox-1.3 protein identifies a binding site 144 bp upstream from the start of transcription.
(20) The homeodomain is identical to the genomic sequence for Hox 1H, a newly identified member of the Hox 1 locus (Acampora et al.
Hoy
Definition:
(n.) A small coaster vessel, usually sloop-rigged, used in conveying passengers and goods from place to place, or as a tender to larger vessels in port.
(interj.) Ho! Halloe! Stop!
Example Sentences:
(1) Jason Kenny's campaign in the match sprint will not end until Monday assuming all goes well, but he got off to the best possible start when he set a new Olympic record in qualifying over the flying 200m, bettering Sir Chris Hoy's 9.815sec from Beijing by over a tenth of a second.
(2) Baugé's body language afterwards indicated he had been on the receiving end of another severe psychological blow; both men progressed to the quarter-finals, but Kenny has already shown that he amply merits his selection ahead of the defending champion, Hoy.
(3) Hoy and others fear that the Kincora inquiry, which is based in Northern Ireland and taking hearings at the court in Banbridge, County Down, will not have access to sensitive MI5 intelligence files on the people who ran Kincora.
(4) That is why many Mexicans are very disconnected with the Galaxy,” said Eduard Cauich, sports editor for Hoy, a Spanish-language weekly published by the Los Angeles Times.
(5) "Governments must show all the energy and cunning of Chris Hoy and Mo Farah until they win [the fight]," he told the audience.
(6) plcS mapped approximately at 67 min on the 75-min chromosomal map (B. W. Holloway, K. O'Hoy, and H. Matsumoto, p. 213-221, in S. J. O'Brien, ed., Genetic Maps 1987, vol.
(7) As Hoy sees it, increasing the number of track cyclists boils down to one issue: access.
(8) The MPs must have felt they were being addressed by the Old Man of Hoy.
(9) Kenny was selected because he has a proven record of rising to the occasion for major championships and because it was believed that his youth would enable him to recover more quickly than Hoy between matches in a tournament where the first two legs in the final were separated by 15 minutes.
(10) Previous behavioral assays showed that crickets discriminate the low frequencies of the species calling song (4-5 kHz) from the high frequencies contained in the vocalizations of insectivorous bats (Nolen and Hoy, 1986a).
(11) British cycling team thrown into chaos by departure of Shane Sutton Read more The Australian, who mentored Sir Chris Hoy and Sir Bradley Wiggins to Olympic success before taking over the top role in British Cycling in 2014, was already under scrutiny after allegations of sexism made by the track rider Jess Varnish at the weekend.
(12) All right, maybe Bradley Wiggins, Chris Hoy and Jessica Ennis will sneak ahead of the mayor at the finish line.
(13) A unique source of ipsilaterally mediated inhibition, tuned to the calling song frequency, accounted for the poor response to calling song and hence the neuron's high-frequency selectivity, and the behavioral and physiological effects of 2-tone suppression of high frequencies by the calling song (Nolen and Hoy, 1986b).
(14) As a result, five of the best 10 qualifiers from the world championships were absent here, including Hoy, who took bronze at the world's behind Baugé and Kenny.
(15) Hoy now stands alone, a national hero, as the only man who has won three gold medals on two wheels in a single Olympic games, but countless other cyclists have felt the same as he did after five minutes whirling round the bankings: "There was a sudden acceleration, a burst of speed, and I was hooked.
(16) Part of the London gold rush was dependent on two riders at the end of their careers – Sir Chris Hoy and Victoria Pendleton.
(17) Hoy is an enthusiastic proponent of his sport: "It's exhilarating as you fly down the bankings.
(18) The establishment of the fund represents the largest single injection of public money into cycling in England, and was due to be formally launched by Cameron alongside Britain's most successful Olympian, the track cyclist Chris Hoy.
(19) The 24-year-old's status as the stealth champion of British cycling – compared to the cover stars Hoy, Pendleton and Wiggins – looked set to change after the coaches made their unexpected call in June and it will certainly change now.
(20) Certainly the newspaper Hoy, Diario del Magdalena had little doubt who was to blame for their defeat.