(superl.) Very large; enormous; immense; excessive; -- used esp. of material bulk, but often of qualities, extent, etc.; as, a huge ox; a huge space; a huge difference.
Example Sentences:
(1) Handing Greater Manchester’s £6bn health and social care budget over to the city’s combined authority is the most exciting experiment in local government and the health service in decades – but the risks are huge.
(2) The Pan American Health Organization, the Americas arm of the World Health Organization, estimated the deaths from Tuesday's magnitude 7 quake at between 50,000 and 100,000, but said that was a "huge guess".
(3) Even if it were not the case that police use a variety of tricks to keep recorded crime figures low, this data would still represent an almost meaningless measure of the extent of crime in society, for the simple reason that a huge proportion of crimes (of almost all sorts) have always gone unreported.
(4) To many he was a rockstar, to me he was simply 'Dad', and I loved him hugely.
(5) The matter is now in the hands of the Guernsey police and the law officers.” One resident who is a constant target of the paper and has complained to police, Rosie Guille, said the allegations had a “huge impact on morale” on the island.
(6) "We have peace in Sierra Leone now, and Tony Blair made a huge contribution to that," said Warrant Officer Abu Bakerr Kamara.
(7) The size of Florida makes the kind of face-to-face politics of the earlier contests impossible, requiring instead huge ad spending.
(8) To augment the in vitro expansion of LAK cells, we added highly purified human recombinant interleukin-2, phytohemagglutinin and accessory cells (Uc cells) to the LAK culture system, with which huge number of LAK cells (LAK-L) were generated from originally small number of peripheral blood lymphocytes of cancer patients.
(9) The difference in Brazil will be the huge distances involved, with the crazy decision not to host the group stages in geographical clusters leading to logistical and planning nightmares.
(10) We are in the middle of the third year of huge cuts in acute hospitals' budgets," said Porter.
(11) While there has been almost no political reform during their terms of office, there have been several ambitious steps forward in terms of environmental policy: anti-desertification campaigns; tree planting; an environmental transparency law; adoption of carbon targets; eco-services compensation; eco accounting; caps on water; lower economic growth targets; the 12th Five-Year Plan; debate and increased monitoring of PM2.5 [fine particulate matter] and huge investments in eco-cities, "clean car" manufacturing, public transport, energy-saving devices and renewable technology.
(12) But it is a huge logistical problem – unique in the world.
(13) It may not point to independence – nor, given that large swaths of Wales remain firmly dominated by Labour, mean any huge advance for Plaid Cymru.
(14) Half a million homes were sold in Scotland, we lost a huge, huge chunk of stock, and as house prices began to escalate so any asset to the community has gone.
(15) There must also be strict rules in place to reduce the risks they take with shareholders' funds.Yet the huge cost of increasing capital and liquidity is forgotten when the Treasury urges them to increase lending to small and medium businesses.
(16) Toxicity has been reported in the fetus of a woman ingesting a huge overdose of digitoxin; the same result would be anticipated with digoxin poisoning.
(17) All became highly managed, "domesticated" landscapes that demanded a huge input of labour to build and maintain.
(18) Fine, but the most important new political fact is the unprecedented wave of support that has latched on to Corbyn: the hundreds of thousands who joined Labour, the thumping majority that handed him the leadership, the huge sections of the country that have tuned out of Westminster droid-talk.
(19) Calum MacLean, Grangemouth Petrochemicals chairman, says, “This is a hugely sad day for everyone at Grangemouth.
(20) I’m so happy to be joining Arsenal, a club which has a great manager, a fantastic squad of players, huge support around the world and a great stadium in London,” said Sánchez.
Substantial
Definition:
(a.) Belonging to substance; actually existing; real; as, substantial life.
(a.) Not seeming or imaginary; not illusive; real; solid; true; veritable.
(a.) Corporeal; material; firm.
(a.) Having good substance; strong; stout; solid; firm; as, substantial cloth; a substantial fence or wall.
(a.) Possessed of goods or an estate; moderately wealthy; responsible; as, a substantial freeholder.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.