(n.) Any one of a series of nitrogenous bases, resembling the amines and produced by the reduction of certain nitroso and diazo compounds; as, methyl hydrazine, phenyl hydrazine, etc. They are derivatives of hydrazine proper, H2N.NH2, which is a doubled amido group, recently (1887) isolated as a stable, colorless gas, with a peculiar, irritating odor. As a base it forms distinct salts. Called also diamide, amidogen, (or more properly diamidogen), etc.
Example Sentences:
(1) The first comprises N1-[4-(4-alkyloxybenzamido)benzoyl]-N2-substituted alkylidene hydrazine, the second involves 1-[4-(4-alkyloxybenzamido)benzoyl]-4-alkyl, aryl, or aralkyl-3-thiosemicarbazides, and the third includes 1-substituted-5-[4-(4-alkyloxybenzamido)phenyl]-1,3,4-triazole-2-t hione.
(2) High resolution proton NMR spectroscopic analysis of urine also revealed resonances from several metabolites of hydrazine, an N-acetylcysteine conjugate of allyl alcohol, and acetamide as a metabolite of thioacetamide after dosing with the respective compounds.
(3) When hydrazine was used as the electron donor, no substrate inhibition was observed, suggesting that the inhibition resulted from reductant limitation.
(4) The hydrazine moiety liberated from isoniazid is primarily acetylhydrazine, and studies in animals show this metabolite to be converted to a potent acylating agent that produces liver necrosis.
(5) The weekly administration of 1,2-dimethyl-hydrazine (DMH) by subcutaneous injection for a period of 16-20 weeks is a well known procedure for producing colonic tumors in mice and rats.
(6) The compounds were obtained by condensation of appropriate hydrazines with thiophene 2-carboxaldehyde (series 1), thiophene 3-carboxaldehyde (series 2), and 5-nitrothiophene-2-carboxaldehyde (series 3).
(7) After inhibition of monoamine synthesis by N'-(DL-SERYL)-N2-(2, 3, 4-trihydroxybenzyl)hydrazine, substance P significantly accelerated the disappearance of dopamine, noradrenaline and 5-hydroxytryptamine.
(8) Embryotoxicity has been demonstrated at very high exposures but not at occupationally encountered levels for hydrazine and unsymmetrical dimethylhydrazine.
(9) The characterization of the various disaccharides by Smith periodic acid degradation and glycosidase digestions was facilitated by the preparation and thin-layer chromatographic resolution of the complete series of monosulfated derivatives of anhydromannitol and anhydrotalitol; the sulfate esters were shown to be stable to both the hydrazine and nitrous acid treatments.
(10) This inactivation was very rapid but reversible, with regeneration of enzyme activity being spontaneous and hydrazine-accelerated, suggestive of the intermediacy of a stable acyl enzyme.
(11) Urinary excretion (0-24 h) of hydrazine and its metabolite acetylhydrazine were determined employing nitrogen-phosphorus detection of the adducts utilising a novel internal standard, pentafluorophenylhydrazine, the adduct of which structurally resembles DFBA.
(12) Modification of uridines with hydrazine has no effect on interaction with the enzyme, except for one uridine near the 3'-end of tRNA(Gly).
(13) With a specific gas chromatographic assay procedure, the amount of hydrazine in the 0- to 24-hr urine was determined in patients treated with various doses of hydralazine.
(14) A chromophoric hydrazide, 4'-N,N-dimethylamino-4-azobenzene sulfonyl hydrazide (DABS-hydrazide), was prepared from 4'-N,N-dimethylamino-4-azobenzene sulfonyl chloride by reaction with hydrazine.
(15) A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed.
(16) Hydrazine sulfate compared with placebo addition to chemotherapy resulted in significantly greater caloric intake and albumin maintenance (P less than .05).
(17) The synthesis was achieved by reacting 3-benzylthiazolidin-2-one-4-thione with its 4-hydrazone derivative to give N,N'-bis(3-benzyl-2-oxo-4-thiazolidinylidene)hydrazine, which was subjected to dibromination followed by reaction with various primary aromatic amines.
(18) This study has demonstrated that the nasal respiratory epithelia of rats and hamsters are the most sensitive tissues to the tumorigenic action of hydrazine following inhalation exposures.
(19) In the study in mice described below, which was carried out according to modern guidelines, no carcinogenic action was detected for hydrazine even after the administration of toxic doses over the entire lifespan of the animals.
(20) It is concluded that hydrazine acts to produce and altered base, possibly N(4)-aminocytosine, that produces mutations by mispairing at replication rather than by error-prone repair.
Rocket
Definition:
(n.) A cruciferous plant (Eruca sativa) sometimes eaten in Europe as a salad.
(n.) Damewort.
(n.) Rocket larkspur. See below.
(n.) An artificial firework consisting of a cylindrical case of paper or metal filled with a composition of combustible ingredients, as niter, charcoal, and sulphur, and fastened to a guiding stick. The rocket is projected through the air by the force arising from the expansion of the gases liberated by combustion of the composition. Rockets are used as projectiles for various purposes, for signals, and also for pyrotechnic display.
(n.) A blunt lance head used in the joust.
(v. i.) To rise straight up; said of birds; usually in the present participle or as an adjective.
Example Sentences:
(1) It’s the same story over and over.” Children’s author Philip Ardagh , who told the room he once worked as an “unprofessional librarian” in Lewisham, said: “Closing down a library is like filing off the end of a swordfish’s nose: pointless.” 'Speak up before there's nothing left': authors rally for National Libraries Day Read more “Today proves that support for public libraries comes from all walks of life and it’s not rocket science to work out why.
(2) Guy Jobbins, a Cairo-based British water scientist who heads Canada's International Development Research Centre climate change adaptation programme for Africa, says understanding of the issue has rocketed in the past few years.
(3) The group was one of the few in Syria to have received anti-tank rockets and had regularly used them against Syrian armour.
(4) In the same way, using the anti-trimethylamine-N-oxide reductase serum, rocket immunoelectrophoresis analyses were able to show that the inducible apoenzyme is not regulated by the fnr gene product and that molybdate does not seem necessary for the synthesis or stabilisation of this enzyme.
(5) In 13 patients complement C3d was determined by rocket immunoelectrophoresis.
(6) "The Afghan people dared rockets and bombs, but they came out and voted and that's great."
(7) After two bodyguards of British ambassador Dominic Asquith were wounded in a rocket attack on the UK consulate, London closed its mission down.
(8) Within the last half hour Haaretz reported a home in the city was hit by a rocket and that one person is being treated for shock.
(9) A rocket also caused the first serious Israeli casualty – one of eight people hurt when a fuel tanker was hit at a service station in Ashdod, 20 miles north of Gaza.
(10) Barack Obama's policy of engagement with North Korea lies "in tatters" after it was effectively shot down by Pynongyang's defiant but failed attempt to launch a long-range rocket.
(11) We usually started at 5am taking pictures of the Israeli air strikes and rockets launched by Palestinian militants.
(12) After a frantic period around "Black Friday" sales at the end of November, business quietened down but "took off like a rocket" from Boxing Day when Dixons took £100,000 a minute, chief executive Seb James said.
(13) Although missiles belonging to Hamas and other armed Palestinian groups in Gaza do sometimes fall short, there was no visible evidence of debris from broken Palestinian rockets in the school.
(14) They said US forces had found a "daisy chain"– a long bomb rigged up from mortars, rocket-propelled grenades and a motorbike.
(15) Serum volume in the blood dots was determined by calculation of dot area or by measuring albumin content in the eluted samples by means of rocket immunoelectrophoresis.
(16) If the billions that have been thrown at this programme had been invested in providing teachers with decent, evidence-based training which is “on-the-job”, then standards would have sky-rocketed and we would be vying with the best education systems in the world, such as those in Finland and Singapore.
(17) The concentrations of plasma serine protease inhibitors in monocyte culture supernatants were measured by using rocket immunoelectrophoresis.
(18) I can't say exactly what these are or when (they might be rolled out), but we are in a kind of race [with the Palestinian rocket firers] and we always need to update (the system) to increase the probability of a kill."
(19) Israel rejects these efforts as politically motivated, saying it acted in self-defence against Hamas rocket attacks from Gaza.
(20) The two systems tried were rocket immunoelectrophoresis, carried out after reduction of samples with dithiothreitol and using monomeric IgA as standard, and a radioimmunoassay utilising a double antibody precipitation method and polymeric IgA as standard.