(n.) A compound radical, or unsaturated group, HO, consisting of one atom of hydrogen and one of oxygen. It is a characteristic part of the hydrates, the alcohols, the oxygen acids, etc.
Example Sentences:
(1) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(2) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(3) The coatings formed contain only stable chemical bonds (e.g., C-C, C-O-C), and easily-derivatized hydroxyl moieties.
(4) The efficacy of both PCBOH I and III derivatives required the presence of a hydroxyl moiety and increased directly with the degree of chlorination.
(5) tert-Butyl hydroaminoxyl is detected as a degradation product of the hydroxyl adduct from all spin traps.
(6) A method for the introduction of side chains containing isonitrile (isocyanide, functional group) on the backbone of polysaccharides and other hydroxylic polymers was developed.
(7) P-1894B dose dependently reduced the hydroxylation of peptidyl proline in the fibrotic liver.
(8) The 1-carboxyalkyl nicotinamide----dihydronicotinamide redox pair is a new type of brain-enhanced chemical delivery system for drugs containing hydroxyl groups.
(9) Both adiphenine.HCl and proadifen.HCl form more stable complexes, suggesting that hydrogen bonding to the carbonyl oxygen by the hydroxyl-group on the rim of the CD ring could be an important contributor to the complexation.
(10) Enzyme-inhibiting ability for individual alkylphenols can be estimated based on the quantitative structure-activity relationship developed by Dewhirst (1980) and is a function of the free hydroxyl group, electron-donating ring substituents, and hydrophobic aromatic ring substituents.
(11) Samples of rockwool and glass fibre were compared with chrysotile fibres for their capacity to hydroxylate 2-deoxyguanosine to 8-hydroxydeoxyguanosine, a reaction that is mediated by formation of hydroxyl radicals.
(12) aldrin epoxidation, ethylmorphine demethylation, and benzo(a)-pyrene hydroxylation were induced under these conditions.
(13) Cytochrome P-450 IVA1 (or a very closely related isoenzyme in the same gene family) was a major constitutive haemoprotein in rat kidney microsomes and actively supported the omega-hydroxylation of lauric acid.
(14) In vitro sensitizing activities were correlated to the promotion efficiency of radiolytic hydroxylation of thymine to thymine glycol and to the one-electron reduction potential of a variety of fluorinated and non-fluorinated nitroazole derivatives.
(15) Ring hydroxylated saterinone and three metabolites that were not identified made up about 1-4% each.
(16) Nafimidone and other 1-imidazoles were shown to be potent inhibitors of phenytoin p-hydroxylation in rat hepatic microsomes, being very effective even at submicromolar concentrations.
(17) Only pretreatment of rabbits with rifampicin, which induces cytochrome P-450 form 3c (P-450IIIA6), significantly increased the microsomal hydroxylation of tolbutamide.
(18) Synthesis with denatured DNA as template presumably proceeds from 3'-hydroxyl termini formed at loop-back regions since the synthesized DNA product and template are covalently linked.
(19) Here we report that phenol hydroxylation to hydroquinone is also catalyzed by human myeloperoxidase in the presence of a superoxide anion radical generating system, hypoxanthine and xanthine oxidase.
(20) Mössbauer spectroscopy has been used to study the heme iron in various states of cytochrome P450cam from the camphor-hydroxylating system of the bacterium Pseudomonas putida.
Predicament
Definition:
(n.) A class or kind described by any definite marks; hence, condition; particular situation or state; especially, an unfortunate or trying position or condition.
(n.) See Category.
Example Sentences:
(1) I can’t stay here anymore.” When his mother calls, he says, he refuses to talk to her, blaming her in part for his predicament.
(2) I had told Chris that I would need an electric hook-up and told him about my predicament.
(3) As one example, certain aspects of Gawain's situation seem oddly redolent of a more contemporary predicament, namely our complex and delicate relationship with the natural world.
(4) How are medical roles adapted to the situation of medical pluralism and the predicaments that flow from such a situation.
(5) High tension and high stakes coursed through this meeting of top four chasers versus relegation facers and it was to QPR’s credit that they attacked their predicament – and Arsenal – head on.
(6) Clinical research and opinion in this area have elicited both clinical euphoria and polarization vis-a-vis newer possibilities for resolving the predicaments of partial or complete edentulism.
(7) who was thinking about voting yes, and went on to reduce her political predicament to her meagre wage packet.
(8) Craving boldness is too often a euphemism for wishing Labour's predicament were something other than what it is; that there was a way to promise immediate improvement in everyone's lives without giving them money.
(9) When there was no accordance, we noticed a correlation between pressure gradient and surgical success in 3 cases and predicaments based on PRA and success in 2 cases.
(10) But the predicament is partly engendered by prosperity, too.
(11) The Canadian researchers were more sympathetic to the IGDA’s predicament than Kazemi or the workers spoken to for this feature.
(12) The former chairman blamed "mismanagement" for the retailer's dire predicament, and is interested in acquiring some of its stores to add to his DW Sports Fitness chain.
(13) Jack is played with dreamy intensity and later (as the realities of criminal life begin to kick in) with steely resolve by LaBeouf, who must be able to sympathise with Jack's predicament.
(14) If you pull one side, your feet are in the cold.” Quite how long Hazard – who did manage seven minutes off the bench – is shivering out in the wilderness remains to be seen but Chelsea’s predicament requires a creative talent who signed a new five-and-a-half-year contract in February to emulate Willian and Pedro, allying discipline to those mind-boggling flashes of skill.
(15) Caroline Lucas MEP is leader of the British Green party President Mohamed Nasheed Despite our predicament, I'm optimistic The Maldives doesn't look like the front line in a battle.
(16) If [policing is] the only type of process that they want to put in place to address these issues, then we will have a major concern with it, because that will not … address the issues and we will be in the same predicament a month from now or a year from now,” Dandan said.
(17) But, despite the sympathy felt by many in Europe for Scotland’s predicament, Sturgeon’s hopes of ensuring the country remains in the bloc look likely to be crushed.
(18) We have to try and find a way to help the audience sympathise with his predicament."
(19) So the first problem was that the Greek cuts led to a worsening of the Greek predicament: the economy kept contracting, and unemployment hit a record high of 16.2%.
(20) Until we are mathematically gone, I will believe.” Tottenham’s Son Heung-min grabs late winner after Watford red card Read more He also said he will do his utmost to entice reinforcements during the January transfer window, but admits that the club’s predicament complicates recruitment.