(n.) A compound radical, or unsaturated group, HO, consisting of one atom of hydrogen and one of oxygen. It is a characteristic part of the hydrates, the alcohols, the oxygen acids, etc.
Example Sentences:
(1) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(2) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(3) The coatings formed contain only stable chemical bonds (e.g., C-C, C-O-C), and easily-derivatized hydroxyl moieties.
(4) The efficacy of both PCBOH I and III derivatives required the presence of a hydroxyl moiety and increased directly with the degree of chlorination.
(5) tert-Butyl hydroaminoxyl is detected as a degradation product of the hydroxyl adduct from all spin traps.
(6) A method for the introduction of side chains containing isonitrile (isocyanide, functional group) on the backbone of polysaccharides and other hydroxylic polymers was developed.
(7) P-1894B dose dependently reduced the hydroxylation of peptidyl proline in the fibrotic liver.
(8) The 1-carboxyalkyl nicotinamide----dihydronicotinamide redox pair is a new type of brain-enhanced chemical delivery system for drugs containing hydroxyl groups.
(9) Both adiphenine.HCl and proadifen.HCl form more stable complexes, suggesting that hydrogen bonding to the carbonyl oxygen by the hydroxyl-group on the rim of the CD ring could be an important contributor to the complexation.
(10) Enzyme-inhibiting ability for individual alkylphenols can be estimated based on the quantitative structure-activity relationship developed by Dewhirst (1980) and is a function of the free hydroxyl group, electron-donating ring substituents, and hydrophobic aromatic ring substituents.
(11) Samples of rockwool and glass fibre were compared with chrysotile fibres for their capacity to hydroxylate 2-deoxyguanosine to 8-hydroxydeoxyguanosine, a reaction that is mediated by formation of hydroxyl radicals.
(12) aldrin epoxidation, ethylmorphine demethylation, and benzo(a)-pyrene hydroxylation were induced under these conditions.
(13) Cytochrome P-450 IVA1 (or a very closely related isoenzyme in the same gene family) was a major constitutive haemoprotein in rat kidney microsomes and actively supported the omega-hydroxylation of lauric acid.
(14) In vitro sensitizing activities were correlated to the promotion efficiency of radiolytic hydroxylation of thymine to thymine glycol and to the one-electron reduction potential of a variety of fluorinated and non-fluorinated nitroazole derivatives.
(15) Ring hydroxylated saterinone and three metabolites that were not identified made up about 1-4% each.
(16) Nafimidone and other 1-imidazoles were shown to be potent inhibitors of phenytoin p-hydroxylation in rat hepatic microsomes, being very effective even at submicromolar concentrations.
(17) Only pretreatment of rabbits with rifampicin, which induces cytochrome P-450 form 3c (P-450IIIA6), significantly increased the microsomal hydroxylation of tolbutamide.
(18) Synthesis with denatured DNA as template presumably proceeds from 3'-hydroxyl termini formed at loop-back regions since the synthesized DNA product and template are covalently linked.
(19) Here we report that phenol hydroxylation to hydroquinone is also catalyzed by human myeloperoxidase in the presence of a superoxide anion radical generating system, hypoxanthine and xanthine oxidase.
(20) Mössbauer spectroscopy has been used to study the heme iron in various states of cytochrome P450cam from the camphor-hydroxylating system of the bacterium Pseudomonas putida.
Xylenol
Definition:
(n.) Any one of six metameric phenol derivatives of xylene, obtained as crystalline substances, (CH3)2.C6H3.OH.
Example Sentences:
(1) These criteria are applied to para-chloro-meta-xylenol (PCMX), a compound used with increasing frequency in health care personnel handwashing agents.
(2) Calcein, calcein blue, and xylenol orange produced green, blue, and red fluorescence, respectively.
(4) This manuscript reports the results of an investigation into the suitability of the ferrous sulfate-benzoic acid-xylenol orange (FBX) dosimeter for measurement of small absorbed doses caused by radionuclide solutions mixed with the dosimeter solution.
(5) The regulation of the inducible set of gentisate pathway enzymes used by Pseudomonas alcaligenes (P25X1) has been studied in strains derived from mutant strains of P25X1 that had lost the constitutive enzymes that degrade m-cresol, 2,5-xylenol and 3,5-xylenol.
(6) After extractive acetylation, the derivatives of all cresols and xylenols were completely separated on a Se-54 capillary column.
(7) An automated method, based on the chelating reaction of calcium disodium edetate with zirconium and the subsequent determination of excess zirconium reacted with xylenol orange, was developed.
(8) Two distinct NAD+-dependent m-hydroxybenzyl alcohol dehydrogenases were purified from cells grown on 3,5-xylenol.
(9) Twenty-four-hour IC50 values (50% immobilization concentration) for phenol, o-cresol, m-cresol, p-cresol, six xylenols, and three trimethylphenols were determined for Daphnia magna under static conditions.
(10) The oxidation product of 2,5-xylenol was identified as 3-hydroxy-4-methylbenzoic acid.
(11) In ten patients with severe chronic bronchitis and in a further 23 with planned resection of lung, tonsils or larynx, 500 mg doses, single or multiple, of xibornol (6-isobronyl-3, 4-xylenol) were administered for an antibacterial effect.
(12) Bone formation of fractured fibulae stimulated by pulsed electromagnetic fields (PEMF), PGE2, and combination of both was assessed with roentgenography and fluorescent labelling compounds, tetracycline, xylenol orange, and calcein.
(13) The filtrate is evaporated to dryness, redissolved in water, and reacted with 2,4-xylenol in the presence of sulfuric acid to form 6-nitro-2,4-xylenol.
(14) The addition of the laccase reversed the inhibitory effect of 2,6-xylenol, 4-chloro-2-methylphenol, and p-cresol.
(15) The fluorescent calcium binding dyes xylenol orange, calcein green, and tetracycline were used successfully to sequentially label new bone deposition and bone remodeling during the healing of rigidly fixed humeral fractures in the chicken.
(16) The calcium binding fluorochromes calcein, calcein blue, and xylenol orange were investigated, with each fluorochrome being included in the alkaline phosphatase incubating medium and used in a single-step procedure.
(17) When supplemented with ATP, CoA, succinate and Mg(2+) ions, an enzyme system from cells grown with 2,5-xylenol formed pyruvate from d- but not from l-citramalate.
(18) Several vital dyes are used (tetracycline, calcein, alizarin, xylenol), but it is not known whether the histomorphometric results they provide are equivalent.
(19) No cross sensitivity to 4-chloro-3,5 xylenol was seen.
(20) Complete separation of the mixture has been obtained, except for phenol and o-cresol and o-ethylphenol and 3,5-xylenol whose peaks overlapped, and 2- and 3-methylindoles which were poorly separated.