(n.) An increase in, or excessive growth of, the normal elements of any part.
Example Sentences:
(1) Weddellite calcification was associated with benign lesions in 16 cases, but incidental atypical lobular hyperplasia and lobular carcinoma in situ were present, each in one case.
(2) One must be suspicious of any gingival lesion, particulary if there is a sudden onset of bleeding or hyperplasia.
(3) The vulvar white keratotic lesions which have been subjected to histological examination in Himeji National Hospital (1973-1987) included 13 cases in benign dermatoses, 4 cases in vulvar epithelial hyperplasia, 3 cases in lichen sclerosus, and 3 cases in lichen sclerosus with foci of epithelial hyperplasia.
(4) Using an antibody to the nerve growth factor receptor (NGFR), we examined dendritic reticulum cells (DRCs) immunohistochemically in 62 formalin-fixed, paraffin-embedded lymph nodes from patients with reactive follicular hyperplasia or with various types of lymphoma.
(5) A constellation of histologic lesions was identified in brain (diffuse meningoencephalitis with bilaterally symmetrical thalamic necrosis), liver (pericholangiohepatitis), lung (pneumonitis), and spleen (lymphoid hyperplasia); this tetrad is apparently unique to this model system.
(6) Four cases of benign lymphoid hyperplasia (BLH) of the duodenal bulb are reported.
(7) At autopsy, this DOCA-hypertensive rat was found to have a form of hepatitis associated with proliferative activity, i.e., cellular unrest, mitotic figures and oval cell hyperplasia.
(8) In 20 patients (18.2%), visualization revealed uterine abnormalities, mainly newly added endometrial lesions, i.e., hyperplasia, polyps, endometritis, and synechiae.
(9) The left adrenalectomy revealed micronodular hyperplasia but resulted in a prompt and sustained reversal of hypertension and hyperaldosteronism.
(10) Mucosal bleeding and megakaryocytic hyperplasia occurred in all patients.
(11) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
(12) Equine Cushing's disease is caused by an adenomatous hyperplasia of the intermediate pituitary which secretes high levels of beta-endorphin, ACTH, and other peptide derivatives of POMC.
(13) It is clear that some degree of thyroid inhibition can be accommodated within the bounds of the normal feedback mechanism without the induction of either hyperplasia or neoplasia.
(14) Antibodies were almost never present in the absence of conjunctival follicles, but their titres were unrelated to the degree of follicular hyperplasia; there was no obvious relationship between the serological findings and corneal lesions.
(15) In addition, mice exposed to 20 or 60 ppm had hyperplasia of the transitional epithelium lining the urinary bladder.
(16) The patterns of urinary 17-ketosteroids, pregnanediol, pregnanetriol and pregnanetriolone were similar to those commonly seen in congenital adrenal hyperplasia with steroid 21-hydroxylase deficiency.
(17) Water restriction of HYD birds for 5 days as adults stimulated tubule hypertrophy but not to the same extent as the chronic regimen and with no evidence for hyperplasia.
(18) The effects of finasteride in patients with benign prostatic hyperplasia were investigated in 2 double-blind, placebo-controlled studies.
(19) The development of intimal hyperplasia is not excluded, as well as of inflammatory reaction with the following thrombotic occlusion of the artery lumen.
(20) The purpose of this report is to present the kinetics of reduction of epidermal mass following the production of the epidermal hyperplasia as the epidermis returns to its normal thickness during the period of regression.
Hyperplastic
Definition:
(a.) Of or pertaining to hyperplasia.
(a.) Tending to excess of formative action.
Example Sentences:
(1) When TSLP was pretreated with TF5 in vitro, the most restorative effects on the decreased MLR were found in hyperplastic stage and the effects were becoming less with the advance of tumor developments.
(2) In 14 of the patients the imaging results were checked against the histological findings of a subsequent thymectomy, which revealed four thymomas and (with the exception of one normal thymus) hyperplastic changes in all the others.
(3) These early hyperplastic lesions revealed stellate-shaped dilated bile canaliculi lined by blebs and abnormally thick elongated microvilli, a decreased number of microvilli on the sinusoidal surface, a marked increase in smooth endoplasmic reticulum, large nucleoli, and bundles of pericanalicular microfilaments.
(4) Using a silver staining technique (AgNOR technique), we have investigated the nucleolar organizer-associated proteins (NORs) in formalin-fixed paraffin embedded conjunctival specimens of 15 intraepithelial squamous carcinomas, 10 hyperplastic-dysplastic samples and 10 control epithelial fragments; the mean number of intranuclear black dots was determined for each case.
(5) Conversely, in 18 out of 21 hyperplastic prostates, 5 alpha-reductase activity was higher than 3 alpha (beta)-hydroxysteroid dehydrogenase activity.
(6) The activity of 5 alpha-reductase is significantly less in neoplastic compared with hyperplastic tissue.
(7) Ideally, the rule should classify all nonhyperplastic and mildly hyperplastic cases as nonprogressive and all carcinomas as progressive; there were, however, a considerable number of false positives and false negatives based on application of the classification rule to these cases.
(8) The clinical and histological aspects of hypertrophic and hyperplastic gum diseases were examined in order to clarify the aetiopathogenesis of such conditions and facilitate their diagnosis.
(9) The mean in the newborn-to-6-month-old group was 47.59 D; in the 12-18-month-old group it had decreased to 45.56 D. The cornea appears to stabilize at about 54 months, with an average reading of 42.69 D. Evaluation of 11 eyes diagnosed as having persistent hyperplastic primary vitreous revealed that eyes with this diagnosis generally have steeper corneas than normal eyes at any given age.
(10) The effects of adrenocorticotrophic hormone (ACTH) on human adrenocortical steroidogenesis were studied in adrenocortical cells which had been isolated from normal and hyperplastic glands by a technique combining tyrpsin digestion and mechanical dispersion, and incubated in the presence of ACTH or dibutyryl cyclic AMP (dbcAMP).
(11) Careful microscopic examination of end-stage kidneys undergoing dialysis discloses cysts lined with hyperplastic cells.
(12) Fine needle aspirates and touch imprints of 36 hyperplastic (reactive) lymph nodes were tested for the presence of keratin and desmin.
(13) Although mammary tumors were not observed in either the control or the neonatally steroid-treated intact mice, many in the latter groups possessed hyperplastic alveolar-like mammary nodules and other abnormalities.
(14) An 11-year-old girl presented with a refractory hypochromic microcytic anemia, hypoferremia, normoblastic hyperplastic bone marrow, hypergammaglobulinemia, and growth retardation.
(15) The methods are reviewed for obtaining monolayer epithelium cultures both in normal and hyperplastic or malignant prostate glands.
(16) The gamma-GT positive cells may have been squamous cancer cells, dysplastic, hyperplastic or normal epithelial cells seen simultaneously or individually on a smear.
(17) DNA repair response to N-methyl-N'-nitro-N-nitrosoguadine (MNNG) was examined in an organ culture of hyperplastic urinary bladder epithelium, induced by N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) in male F344 rats.
(18) Normal and hyperplastic type II pneumocytes were negative for HPLAP, CEA, and CA 125 but were histochemically positive for nonspecific alkaline phosphatase.
(19) This report concerns an extremely rare case of diffuse hyperplastic oncocytosis of the parotid gland occurring in a 60-year-old Japanese male.
(20) Hyperprolactinemia induced by pituitary grafting resulted in an increase in the pancreatic weights, mainly due to hyperplastic proliferation of the pancreatic acinar glands.