(n.) A condition of excessive fever; an elevation of temperature in a disease, in excess of the limit usually observed in that disease.
Example Sentences:
(1) On the basis of these findings, it is suggested that screening for malignant hyperpyrexia by in vitro pharmacological testing of skeletal muscle should be carried out at 37 degrees C, and should include exposure of the sample to halothane, caffeine, suxamethonium and potassium rather than to halothane alone.
(2) In this case report, NMS and its questionable relation to malignant hyperpyrexia are outlined.
(3) They report a case of hyperpyrexia in a patient receiving psychotropic agents during a summer heat wave; massive muscle destruction (rhabdomyolysis) with myoglobinuria and acute renal failure make this case of particular interest.
(4) Of the various drugs currently suggested for the treatment of malignant hyperpyrexia, dantrolene sodium was the most effective in reversing and inhibiting drug induced contractures in vitro, both in normal muscle and in muscle from patients who are susceptible to malignant hyperpyrexia.
(5) One fo the deceased's children, an identical twin, undergoing an anesthetic, was found to develop malignant hyperpyrexia on exposure to nitrous oxide.
(6) The serum CPK is a useful screening test in families in which malignant hyperpyrexia has occurred.
(7) It is suggested that dantrolene sodium is the drug of choice for lowering the raised myoplasmic calcium concentrations in malignant hyperpyrexia.
(8) Measurements of body temperature, respiratory gas exchange, sweat evaporation rate and circulating levels of catecholamines, lactate, pyruvate, free fatty acids and glucose were made in seven patients susceptible to malignant hyperpyrexia (MHS) and in seven control subjects during 2 h of treadmill walking at 40% of maximum oxygen consumption.
(9) A causal relationship between hyperpyrexia and tumor regression was first suggested in 1866, when Busch reported the cure of a histologically diagnosed sarcoma in a middle-aged woman, following a bout of erysipelas.
(10) In this case, besides the usual manifestations of hyperpyrexia without sweating along with consciousness disorders, features of consumptive coagulopathy, rhabdomyolysis and well marked laboratory liver dysfunction have also been found.
(11) Oral Acyclovir treatment (100 mg, 5 times daily, for 5 days) was efficacious in arresting the hyperpyrexia, the systemic manifestations and the cutaneous lesions at 48 hours after the start of treatment.
(12) The first, of North African origin, was admitted for epigastralgia, hyperpyrexia and intestinal problems.
(13) In contrast to those with normal ALT, the clinical course of the group A patients was more often accompanied by profound hypotension (44 vs. 0%, p less than 0.025), disseminated intravascular coagulation (50 vs. 0%, p less than 0.005), hyperpyrexia (75 vs. 25%, p less than 0.025) and acute renal failure (81 vs. 0%, p less than 0.001).
(14) Use of this test allows separation of susceptible individuals from those not at risk in families of patients who have experienced malignant hyperpyrexia.
(15) It is concluded that a non-depolarizing neuromuscular blocking drug should be used in patients with hyperpyrexia caused by MAOI overdose, because of the generally more favourable experience with these drugs and because of the potential hepatoxicity of dantrolen.
(16) Muscular paralysis and artificial ventilation minimise late physiological changes such as arterial hypotension and hyperpyrexia, and protect against cerebellar damage, but only slightly against neocortical and hippocampal damage.
(17) We attempt to elucidate the role of hyperpyrexia in this disorder.
(18) He was finally bed-ridden and unresponsive, and died of hyperpyrexia and general wasting at 37 years of age.
(20) The caffeine contracture of normal human muscle, which has been used as a model for malignant hyperpyrexia, is greatly potentiated by halothane.
Pyrexia
Definition:
(n.) The febrile condition.
Example Sentences:
(1) Host responses and neuroendocrinological changes during pyrexia in childhood were studied.
(2) These findings suggest that oral or axillary temperature measurements are inadequate screening tests for pyrexia in the elderly.
(3) An outbreak of the pruritus, pyrexia, haemorrhagic syndrome affected eight of a herd of 175 cows which was divided into two groups of 115 and 60 according to yield.
(4) A 59-year-old woman hospitalised because of dyspnea and a heart murmur in a context of pyrexia was found to have evidence of obstruction of the pulmonary arterial system, clearly defined by ultrasonography, catheterisation and angiography and Imatron scan.
(5) Wound infection, wound haematoma and one unexplained pyrexia were the only complications seen.
(6) When the colostrum-deprived newborn calves immunized with the rs-52 strain were challenged with the virulent NMK7 strain of BRS virus, they exhibited no pyrexia or other abnormal clinical signs at all.
(7) A 22-year-old man presented with multiple raised erythematous skin lesions, pyrexia and epistaxis.
(8) An intermittent pyrexia was also seen without infective etiology.
(9) The indirect hemagglutination test is of diagnostic value in cases with involvement of the internal organs or pyrexia of unknown origin.
(10) They all developed high temperatures, pyrexia, diarrhoea, vomitting or itching and some had convulsions.
(11) Disseminated aspergillosis attributable to Aspergillus deflectus was diagnosed in a Springer Spaniel with lethargy, lameness, anorexia, weight loss, pyrexia, lymphadenopathy, hematuria, and urinary incontinence.
(12) Toxic reactions included pyrexia, headache, and malaise, which were mild to moderate.
(13) The morbidity including postoperative pyrexia revealed no difference between drained and undrained patients.
(14) It revealed that the adverse reactions were nausea, vomiting, abdominal colic, diarrhea, dizziness, headache and pyrexia.
(15) Two children presented with pyrexia, macular erythroderma, vomiting, hypotension and rapid deterioration of consciousness.
(16) Although the mechanism is not yet understood, it appears to be a coincidence of delayed hypersensitivity of the tuberculin type and a less-delayed phenomenon of excessive local edema associated with local lymphadenopathy and short-lasting symptoms of malaise and pyrexia.
(17) All the infected heifers developed clinical trypanosomiasis manifested by massive parasitaemia, fluctuating pyrexia, anaemia, dull hair coat, emaciation, jugular pulse and enlarged superficial lymph nodes.
(18) A positive reaction was noted in 92 of 481 ophthalmological cases; two of 17 lymphadenopathy cases; none in 36 cerebral palsy cases and four of 40 miscellaneous cases comprising pyrexia of unknown aetiology, recurrent abortions etc.
(19) The only manifestation of infection of the baby's mother was a slight pyrexia three days before delivery which subsided quickly after treatment with ampicillin.
(20) Both viruses caused persistent pyrexia and leukopenia, the NSW strain 4 to 5 days and the virulent strain 3 days, after inoculation.