(1) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(2) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(3) The pharmacological examination showed that the new compounds are deprived of the hypnotic activity characteristic for 3,3'-spirobi-5-methyltetrahydrofuranone-2 (2) and behaved in most tests as tranquillizers.
(4) to avoid inhibition of 'natural' responses by anxiety due to the laboratory setting, we made use of post-hypnotic suggestions regarding the nature of the stimuli the subjects were to expect.
(5) 3 alpha-hydroxylated pregnane steroids have been shown to possess anesthetic, hypnotic, anticonvulsant and anxiolytic properties.
(6) Non-benzodiazepine hypnotics may be useful alternatives and our group has undertaken double-blind comparative trials with two such compounds, namely zopiclone and zolpidem.
(7) Thus, with its 'intermediate' elimination half-life, loprazolam would appear to have some potential advantages over both long- and short-acting hypnotics in selected patients, although further studies are needed to fully elucidate its place in therapy.
(8) On the other hand, thiazolidone derivatives are reported to have anesthetic, anticonvulsant, and hypnotic activity.
(9) The most thorough and clinically relevant approach to hypnotic drug evaluation is one that balances the strengths and weaknesses of clinical trials and sleep laboratory evaluations.
(10) Contrary to other studies, central nervous system stimulants are not the most widely prescribed psychoactive drugs in childhood and adolescence, but rather, minor tranquilizers, sedatives and hypnotics are the most widely prescribed psychoactive drugs.
(11) Erickson's utilization approach provides a model of hypnotic and strategic intervention for persons seeking psychotherapy because of sexual orientation confusion.
(12) Previously, we demonstrated that dexmedetomidine, an alpha 2 agonist, produces a hypnotic-anesthetic response in rats via activation of central alpha 2 adrenoceptors and that this response could be enhanced by the alpha 1 antagonist prazosin.
(13) Ten kinds of uracil derivatives showed hypnotic activity.
(14) We suggest that GHB may serve as the prototype for a new class of hypnotic compounds derived from natural sources and capable of activating the neurological mechanisms of normal human sleep.
(15) The steroid anesthetic alphaxalone and a series of naturally occurring analogs were compared in potency and efficacy with each other and the hypnotic barbiturate pentobarbital for interaction with gamma-aminobutyric acid (GABA) receptors:binding sites in rat brain membranes and functional activity in 36Cl- flux measurements with rat hippocampal slices.
(16) An attempt was made to construct and validate a questionnaire measure of hypnotic-like experiences based on Shor's (1979) 8-dimension phenomenological analysis of hypnosis.
(17) The literature on the effects of anxiolytic and hypnotic drugs on performance in tasks requiring sustained attention is confusing.
(18) The largest group of insomniac subjects, and the group who most often used hypnotics "frequently and chronically", were women 45 years and older.
(19) Bilateral microinjection of ethanol to the preoptic area of rats causes a dose-dependent hypnotic effect at doses that do not affect brain temperature.
(20) The Hypnotic Induction Profile (HIP) will be discussed as a rapid and efficient method to identify individual resources and develop treatment strategies.
Paralyzed
Definition:
(imp. & p. p.) of Paralyze
Example Sentences:
(1) Two days later the lambs were delivered, given sheep surfactant, paralyzed, and their lungs mechanically ventilated.
(2) Dogs were anesthetized, paralyzed, and mechanically ventilated.
(3) To examine the effects of focally cooling three areas (rostral, intermediate, and caudal) of the ventral medullary surface (VMS) on respiratory oscillations in cervical sympathetic and phrenic nerve activity, 12 cats were anesthetized, vagotomized, paralyzed, and artificially ventilated with 7% CO2 in O2.
(4) The changes in the levels and distribution of gamma- and epsilon-subunit-specific mRNAs in toxin-paralyzed muscle correlate well with the spatial appearance of functional fetal and adult AChR channel subtypes along the muscle fiber.
(5) The spectrum of disabilities attendant to laryngeal paralysis range from mild hoarseness to complete upper airway obstruction depending upon the static position of the paralyzed cord or cords.
(6) The arrangement of the ventral root afferent fibers was investigated in anesthetized and paralyzed cats.
(7) Neural activities were recorded in decerebrate, vagotomized, paralyzed, and ventilated cats.
(8) Intracellular recordings and labelings with horseradish peroxidase (HRP) of inspiratory neurons were performed in decerebrate, paralyzed and ventilated rats.
(9) For all mutants the virus dose required to paralyze 50% of the infected animals was significantly higher than of the parent strain Barty.
(10) Experiments were carried out on 36 urethane-chloralose aneasthesized, paralyzed, vagotomized and artificially ventilated rabbits.
(11) Several procedures have been developed to restore closure of the paralyzed upper eyelid (implantation of gold weights or open wire springs) or to correct lower lid lagophthalmos and ectropion (lower lid tightening with a Bick procedure or insertion of a closed eyelid spring).
(12) Visual response latencies and rise times of X and Y ganglion cells recorded in the optic tract of anaesthetized, paralyzed cats were measured during repeated stimulation with sinusoidal gratings.
(13) All five stages are identified and are the same regardless of whether the animal is unparalyzed or is paralyzed and artificially respired.
(14) Inspiratory bursts were recorded from the phrenic nerve in Macaca fascicularis monkeys paralyzed and ventilated by means of a servoventilator driven by the inspiratory discharge of the phrenic nerve.
(15) The spinal cord injured patient has been the focus of clinical and research efforts to restore functional movement and obtain therapeutic benefits by electric stimulation of upper-motor-neuron paralyzed muscles.
(16) A transient phase of weak immunity was detected prior to the onset of paralysis when induced by relatively low paralyzing doses of polysaccharide.
(17) After 3 months of training it was found that endurance increased from 8 min at a work rate of 0 W to 30 min at a work rate of 40 W. Compared to the cardiovascular responses in non-paralyzed subjects, computerized cycle ergometry was found to be associated with higher relative stresses for a given level of absolute work.
(18) It is important for clinicians to recognize that benign knee joint effusions are likely to be encountered in paralyzed patients.
(19) Successful electrotherapy depends upon an early beginning, the selective stimulation of the paralyzed muscles with exponential current at a sufficiently high intensity under isometric conditions and by avoiding overstretching of the muscles.
(20) Following intubation of the trachea the patient was paralyzed and mechanically ventilated.