What's the difference between hypoxanthin and nitrogenous?

Hypoxanthin


Definition:

  • (n.) A crystalline, nitrogenous substance, closely related to xanthin and uric acid, widely distributed through the animal body, but especially in muscle tissue; -- called also sarcin, sarkin.

Example Sentences:

  • (1) The hprt T-cell cloning assay allows the detection of mutations occurring in vivo in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene of T-lymphocytes.
  • (2) The incorporation of inosine or hypoxanthine into the IMP and ITP has been proved.
  • (3) This method has been used to identify cells with biochemical lesions in the oxidation of propionate, galactose, hypoxanthine and pyruvate; it has allowed us to identify a new variant of methylmalonicaciduria; we believe it can be extended to include other metabolites and pathways.
  • (4) Here we report that phenol hydroxylation to hydroquinone is also catalyzed by human myeloperoxidase in the presence of a superoxide anion radical generating system, hypoxanthine and xanthine oxidase.
  • (5) Regulation of the uric acid-xanthine transport system and the hypoxanthine-adenine-guanine transport system was studied.
  • (6) The oxidation of vitamin E-deficient rat red blood cells (RBCs) induced by the hypoxanthine-xanthine oxidase (HX-XOD) system has been performed in an aqueous suspension.
  • (7) Only the content of uricogenic bases (adenine and hypoxanthine) varied among the test meals.
  • (8) We applied a sensitive, precise liquid-chromatographic method of analysis for inosine, hypoxanthine, and xanthine to the study of fructose metabolism in humans and in rats.
  • (9) The paired cervical and rectal isolates from one patient with uncomplicated gonorrhea differed only with respect to a requirement for hypoxanthine.
  • (10) Two apparent types of alterations of this enzyme were distinguished: (1) increased specific activity with a normal half life as in megaloblastic anemia, and (2) a prolonged half life with or without an elevation of specific activity as in the deficiency of hypoxanthine-guanine phosphoribosyltransferase.
  • (11) Inosine and hypoxanthine release were attenuated at the higher dose of deoxycoformycin.
  • (12) Recovered hybrid cells produced the chick hypoxanthine phosphoribosyltransferase exclusively, as demonstrated by electrophoretic mobility and immunoprecipitation tests, even though no chick chromosomes or chick cell-surface antigens could be identified in the hybrids.
  • (13) In synchronous cells, uracil DNA glycosylase and hypoxanthine DNA glycosylase were induced with an extent of induction (5-6-fold) comparable to that observed for normal human cells.
  • (14) Our aim was to evaluate the sensitivity of human fibroblasts, in comparison with umbilical vein endothelial cells, to two common reactive oxygen metabolites, to superoxide produced by hypoxanthine and xanthine oxidase, and to reagent hydrogen peroxide.
  • (15) Guanosine greater than inosine = hypoxanthine greater than adenosine were taken up with decreasing initial velocities, respectively; adenine was not transported.
  • (16) Etheno-NADP+, 3-acetylpyridine-adenine dinucleotide phosphate, and nicotinamide-hypoxanthine dinucleotide phosphate act as alternative coenzymes for the enzyme.
  • (17) A dramatic increase in the concentrations of adenosine, inosine and hypoxanthine was detected by microdialysis in the dorsal part of hippocampus and in the striatum immediately after 5 min bilateral occlusion of the carotid arteries.
  • (18) If guanine were to be substituted for hypoxanthine in an isogeometrical molecular structure, additional hydrogen bonds could be made between every N-2 and N-7.
  • (19) HPLC tracing of radiolabelled purines or purine nucleosides revealed that adenine, adenosine and hypoxanthine are incorporated into adenine nucleotides and IMP through a similar channel while guanine and guanosine are salvaged into guanine nucleotides via another route.
  • (20) Among the four purine bases, adenine and hypoxanthine have been reported to be more uricogenic than guanine and xanthine.

Nitrogenous


Definition:

  • (a.) Of, pertaining to, or resembling, nitrogen; as, a nitrogenous principle; nitrogenous compounds.

Example Sentences:

  • (1) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
  • (2) The measurement of the intestinal metabolism of the nitrogen moiety of glutamic acid has been investigated by oral ingestion of l-[15N]glutamic acid and sampling of arterialized blood.
  • (3) The induction of cells with two Y chromosomes by nitrogen mustard (NM) was examined.
  • (4) The disappearance of the herbicide, Avadex (40% diallate), from five agricultural soils (differing in either pH, carbon content, or nitrogen content), incubated under sterile and non-sterile conditions, was followed for a period of 20 weeks.
  • (5) Suspensions of isolated insect flight muscle thick filaments were embedded in layers of vitreous ice and visualized in the electron microscope under liquid nitrogen conditions.
  • (6) Airway closure (CV), functional residual capacity (FRC) and the distribution of inspired gas (nitrogen washout delay percentage, NWOD %) and arterial oxygen tension (PaO2) was measured by standard electrodes in eight extremely obese patients before and after weight loss (mean weights 142 and 94 kg, respectively) following intestinal shunt operation.
  • (7) Formula fed infants retained more nitrogen and gained weight faster.
  • (8) Triglyceride (Trigly) in female dogs, glutamic-pyruvic transaminase (GPT) and urea nitrogen (Urea-N) in male dogs tended to increase.
  • (9) Nitrogen retention was curvilinear in relation to metabolic live weight (kg0.75) in both series.
  • (10) Corynebacterium parvum-treated mice produce large amounts of circulating nitrogen oxides and develop a severe liver injury in response to lipopolysaccharide (LPS).
  • (11) Eight men and eight women each performed peak oxygen intake tests on a cycle ergometer breathing ambient air and a mixture of 12% oxygen in nitrogen (equivalent to an altitude of 4400 m) in the two experiments.
  • (12) From this, it was suggested that a negligible amount of oestradiol was released from these compounds and that the oestradiol moiety was useful as a carrier for the nitrogen mustard moiety.
  • (13) The intravenous administration of ovine placental lactogen to pregnant and non-pregnant sheep produced significant acute decreases in plasma free fatty acid, glucose and amino nitrogen concentrations.
  • (14) In contrast, nitrogen incubation did not alter the basal levels of TBA reactants except for a small rise associated with VE deficiency.
  • (15) MCT TPN was found to have some disadvantages, especially with regard to nitrogen balance and plasma albumin levels.
  • (16) Nitrogen mustard (N2M) treatment of rabbits induced neutropenia, and, in ligated ileal loops, it inhibited fluid secretion induced by salmonella or by cholera toxin (CT).
  • (17) For dipeptides containing the amino terminal residues glycine, alanine and phenylalanine, abstraction of the hydrogen from the carbon adjacent to the peptide nitrogen was the major process leading to the spin-adducts.
  • (18) The raw data are obtained by capillary gas chromatography using a nitrogen-phosphorus detector.
  • (19) Total protein, RNA, DNA, nitrogen, free amino acids and water content were determined in both lymphatic organs.
  • (20) This is the first evidence supporting carbon-nitrogen bond formation as the initial site of interaction between the two substrate molecules.

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