What's the difference between hypoxanthin and sarkin?
Hypoxanthin
Definition:
(n.) A crystalline, nitrogenous substance, closely related to xanthin and uric acid, widely distributed through the animal body, but especially in muscle tissue; -- called also sarcin, sarkin.
Example Sentences:
(1) The hprt T-cell cloning assay allows the detection of mutations occurring in vivo in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene of T-lymphocytes.
(2) The incorporation of inosine or hypoxanthine into the IMP and ITP has been proved.
(3) This method has been used to identify cells with biochemical lesions in the oxidation of propionate, galactose, hypoxanthine and pyruvate; it has allowed us to identify a new variant of methylmalonicaciduria; we believe it can be extended to include other metabolites and pathways.
(4) Here we report that phenol hydroxylation to hydroquinone is also catalyzed by human myeloperoxidase in the presence of a superoxide anion radical generating system, hypoxanthine and xanthine oxidase.
(5) Regulation of the uric acid-xanthine transport system and the hypoxanthine-adenine-guanine transport system was studied.
(6) The oxidation of vitamin E-deficient rat red blood cells (RBCs) induced by the hypoxanthine-xanthine oxidase (HX-XOD) system has been performed in an aqueous suspension.
(7) Only the content of uricogenic bases (adenine and hypoxanthine) varied among the test meals.
(8) We applied a sensitive, precise liquid-chromatographic method of analysis for inosine, hypoxanthine, and xanthine to the study of fructose metabolism in humans and in rats.
(9) The paired cervical and rectal isolates from one patient with uncomplicated gonorrhea differed only with respect to a requirement for hypoxanthine.
(10) Two apparent types of alterations of this enzyme were distinguished: (1) increased specific activity with a normal half life as in megaloblastic anemia, and (2) a prolonged half life with or without an elevation of specific activity as in the deficiency of hypoxanthine-guanine phosphoribosyltransferase.
(11) Inosine and hypoxanthine release were attenuated at the higher dose of deoxycoformycin.
(12) Recovered hybrid cells produced the chick hypoxanthine phosphoribosyltransferase exclusively, as demonstrated by electrophoretic mobility and immunoprecipitation tests, even though no chick chromosomes or chick cell-surface antigens could be identified in the hybrids.
(13) In synchronous cells, uracil DNA glycosylase and hypoxanthine DNA glycosylase were induced with an extent of induction (5-6-fold) comparable to that observed for normal human cells.
(14) Our aim was to evaluate the sensitivity of human fibroblasts, in comparison with umbilical vein endothelial cells, to two common reactive oxygen metabolites, to superoxide produced by hypoxanthine and xanthine oxidase, and to reagent hydrogen peroxide.
(15) Guanosine greater than inosine = hypoxanthine greater than adenosine were taken up with decreasing initial velocities, respectively; adenine was not transported.
(16) Etheno-NADP+, 3-acetylpyridine-adenine dinucleotide phosphate, and nicotinamide-hypoxanthine dinucleotide phosphate act as alternative coenzymes for the enzyme.
(17) A dramatic increase in the concentrations of adenosine, inosine and hypoxanthine was detected by microdialysis in the dorsal part of hippocampus and in the striatum immediately after 5 min bilateral occlusion of the carotid arteries.
(18) If guanine were to be substituted for hypoxanthine in an isogeometrical molecular structure, additional hydrogen bonds could be made between every N-2 and N-7.
(19) HPLC tracing of radiolabelled purines or purine nucleosides revealed that adenine, adenosine and hypoxanthine are incorporated into adenine nucleotides and IMP through a similar channel while guanine and guanosine are salvaged into guanine nucleotides via another route.
(20) Among the four purine bases, adenine and hypoxanthine have been reported to be more uricogenic than guanine and xanthine.
Sarkin
Definition:
(n.) Same as Hypoxanthin.
Example Sentences:
(1) For Yusuf Sarkin, the gunfire and the screaming and the frenzy of bodies trying to outrun bullets flying through the sandy streets of Baga blended into one long awful blur.
(2) Sarkin, 51, and his wife grabbed their four children and joined others fleeing Boko Haram’s murderous descent on 3 January.
(3) Sarkin was clutching Adamu’s hand and his family started running.