What's the difference between ichthyosis and xeroderma?
Ichthyosis
Definition:
(n.) A disease in which the skin is thick, rough, and scaly; -- called also fishskin.
Example Sentences:
(1) The results obtained in congenital ichthyosiform erythroderma, lamellar ichthyosis, and Papillon-Lefèvre syndrome were judged as better than those usually reported with etretinate.
(2) In this prospective study, 51 patients suffering from psoriasis and ichthyosis were treated with acitretin for 2 years.
(3) Scaling in patients with recessive X-linked ichthyosis is caused by lack of activity of the enzyme steroid sulfatase.
(4) Skin changes varied from patchy hyperkeratosis to a severe generalized ichthyosis-like condition.
(5) (1984) as autosomal dominant lamellar ichthyosis and thus confirm the existence of this new form of ichthyosis.
(6) Two brothers are described with ichthyosis, hepatosplenomegaly and signs of cerebellar degeneration.
(7) In psoriasis and ichthyosis urea is effective in creams substitution therapy.
(8) Trichothiodystrophy (TTD) is an autosomal recessive disorder characterized by brittle hair with reduced sulfur content, ichthyosis, peculiar face, and mental and physical retardation.
(9) Sex-linked ichthyosis, a rather common genodermatosis, has recently been linked with deficiency of the enzyme steroid sulfatase.
(10) Some biopsy specimens have been diagnosed as showing lamellar ichthyosis, while others have again shown psoriasis.
(11) We study here the case of a male patient aged 22 years with antecedents of Down syndrome and X-linked ichthyosis.
(12) It is concluded that the dry skin often seen in atopic dermatitis may be a mild eczematous lesion of atopic dermatitis, or a manifestation of concomitant ichthyosis, or a complex of these two changes.
(13) Founding Member and Trustee, Ichthyosis Support Group.
(14) In the human there is an X-linked gene affecting steroid sulphatase (STS) activity which, when deficient, is associated with X-linked congenital ichthyosis.
(15) In seborrheic keratoses, allergic contact dermatitis and ichthyosis vulgaris, the cytochrome oxidase activity was greatly reduced or abolished in keratinocytes, Langerhans' cells, and melanocytes, whereas the peroxidase activity was present as in normal epidermis.
(16) A unique disorder characterized by ichthyosis and defects of the appendages and teeth is reported.
(17) Three observations were made: CRBP showed little or no variations whereas CRABP was either normal (seborrheic keratosis, lichenification, nonlesional psoriatic and nonlesional Darier disease skin) or elevated (psoriatic plaques, lamellar ichthyosis, lesional Darier disease, pityriasis rubra pilaris, keratosis pilaris); high levels of CRABP might indicate a greater sensitivity of the lesions to systemic synthetic retinoids with a carboxyl group in the C15 position, and systemic administration of etretin increased the levels of CRABP but not CRBP.
(18) Steroid-sulfatase activity was absent in the cultured fibroblasts of nine affected members of eight families with sex-linked ichthyosis.
(19) The skin of a girl born with the typical appearance of "collodion baby," evolved into an exfoliative erythroderma that clinically was lamellar ichthyosis.
(20) She had striking ichthyosis and detailed investigations into the structure of the epidermis were performed.
Xeroderma
Definition:
(n.) Ichthyosis.
(n.) A skin disease characterized by the presence of numerous small pigmented spots resembling freckles, with which are subsequently mingled spots of atrophied skin.
Example Sentences:
(1) The SCE frequencies of xeroderma pigmentosum (XP12RO) and normal human lymphoblastoid cell lines were also found to be unaffected by Na2SeO3 concentrations that produced elevated SCE frequencies in whole blood cultures.
(2) Fetal autopsy case of xeroderma pigmentosum was reported.
(3) The cytogenetic study of a case of cutaneous squamous cell carcinoma developed in a child affected by xeroderma pigmentosum is described.
(4) Dysplastic naevus syndrome (DNS) is frequently observed in association with familial melanoma and xeroderma pigmentosum (XP), but the role of UV-light in the development of DNS has not been elucidated.
(5) The data indicate that the repair of lesions induced by these substances may have common rate-limiting steps, a conclusion previously indicated by the repair deficiency in xeroderma pigmentosum cells in which a single mutation eliminates the repair of damage caused by each of these agents.
(6) Skin phototesting and cellular sensitivity studies were performed in a patient with xeroderma pigmentosum (XP) complementation group E (XP80TO) at the ages of 50 and 55 years.
(7) Include is a discussion of xeroderma pigmentosum, ataxia-telangiectasia.
(8) This phenomenon is also displayed by xeroderma pigmentosum cells (complementation groups A and F), which are deficient in the excision repair of UV-induced pyrimidine dimers in the DNA.
(9) This syndrome is related to xeroderma pigmentosum complementation group D but differs from it in the absence of skin tumors, at least in the first two decades of life.
(10) Diploid xeroderma pigmentosum (XP) skin fibroblast strains from various XP-complementation groups (B, C, G, and H) were transformed with an origin-defective SV40 early region or with the pSV3 gpt plasmid.
(11) We studied the UV-sensitivity of cultured fibroblast cells derived from these PMD cases, as compared with UV-sensitive Cockayne syndrome (CS) and xeroderma pigmentosum (XP) cells as positive controls.
(12) A genetic model for some cases of excision-deficient xeroderma pigmentosum (XP) is proposed in which the trait (i.e., XP) is expressed if and only if the individual is homozygous or hemizygous for defective alleles at more than one of a specific set of loci.
(13) Patients suffering from the genetic disorder xeroderma pigmentosum (XP) display an extreme sensitivity of their skin to sun (UV) exposure and predisposition to skin cancer due to deficiencies in the excision DNA repair pathway.
(14) The xeroderma cells were competent in their ability to excise 3-methyl adenine adducts.
(15) An apparent linear dose response within the dose range used was observed for UV-induced mutations in both normal and xeroderma pigmentosum fibroblasts.
(16) A 43-year-old man with xeroderma pigmentosum, XP97TO, was allocated to complementation group D. He had had moderate photosensitivity at age 1 year and freckles by age 6 but no neurologic abnormalities.
(17) Extracts from xeroderma pigmentosum (XP) cells are defective in repair synthesis.
(18) No discernible difference could be detected between the fluence-response curves of pyrimidine dimers for untreated and MMC-treated repair-deficient xeroderma pigmentosum cells of group A.
(19) inactivation of transient expression of the bacterial gpt gene contained in a non-replicating expression vector plasmid, pSV2catSVgpt, was much greater in three xeroderma pigmentosum lines than in the four other human cell lines tested.
(20) This activity is absent in xeroderma pigmentosum group A cells.