(1) Moreover, one possible mechanism of intracellular insulin degradation is that cell surface IDE may be internalized with the insulin receptor complex and may degrade insulin during the intracellular process.
(2) These results demonstrate that the IDE is evolutionarily conserved and that its expression is tightly regulated during differentiation of Drosophila.
(3) A ventrally localized melanization inhibiting factor (MIF) has been suggested to play an important role in the establishment of the dorsal-ventral pigment pattern in Xenopus laevis [Fukuzawa and Ide:Dev.
(4) The addition of NADPH to the membranes was shown to result in the conversion of inactive protochlorophyll (ide) absorbing at about 630 nm into a form(s) with light-absorption maxima at about 640 and 652 nm, both of which disappear when chlorophyll (ide) is formed on illumination.
(5) When IDE particles are injected intravenously, the Kupffer cells of the hepatic sinusoids accumulate particles within 10 to 20 minutes, after which the clearance and excretion of IDE takes place.
(6) On the other hand the lingual IDE withdraw from the cell cycle before the corresponding labial cells.
(7) Immunoblotting experiments demonstrate that this inhibition is mediated by the reactivity of these mAbs with a 110 kDa protein, the known M(r) of IDE.
(8) A stereospecific high-performance liquid chromatographic method for the determination of (R,S)-flecainide acetate [(R,S)-N-(2-piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzam ide acetate] in human plasma and urine is described.
(9) A rapid, sensitive high-performance liquid chromatographic method has been developed for the determination of desmosine (DES) and isodesmosine (IDE), the specific cross-linking amino acids of elastin, in the tissue hydrolysates of rats.
(10) Two minutes after injection, intra- and extracellular IDE particles were found in the red pulp of the spleen.
(11) An insulin-degrading enzyme (IDE) was purified from the cytosol of human erythrocytes via the use of ammonium sulfate precipitation and chromatography on columns composed of DEAE-Sephadex, pentylagarose, hydroxylapatite, chromatofocusing resins, and Ultrogel AcA-34.
(12) Since some of these peptides have insulin-like properties, amino acid analysis of these products may enable us to identify not only the splitting position of insulin by IDE but also the site of the hormone for receptor binding.
(13) A fully automated readout unit for the BG-8 blood-grouping machine, printing Idee identification numbers with matching ABO grouping and rhesus (D) typing results is described.
(14) In vitro incubation experiments confirmed that human PMNs ingest IDE particles.
(15) The relaxant effect of cromakalim (BRL 34915), pinacidil and RP 49356 (N-methyl-2-(3-pyridyl)-tetrahydro-thiopyran-2-carbothioamide-1-ox ide) on the sustained contractions induced by 20 mM KCl were compared with the effects of nicorandil.
(16) [4R,(2E,5E)]-3-Hydroxy-2,4,6-trimethyl-2,5,7-octatriene-4-thiol ide, C11H14O2S, Mr = 210.30, hexagonal, P6(5), a = b = 9.8514 (6), c = 19.954 (1) A, V = 1677.1 A3, Z = 6, Dx = 1.249 g cm-3, lambda(Cu K alpha) = 1.5418 A, u = 23.07 cm-1, F(000) = 672, T = 298 K, R = 0.028 for 1021 unique reflections [Fo2 greater than 2 sigma(Fo2)].
(17) Row III IDE cells are also devoid of organelles related to secretory protein synthesis, although these IDE cells accumulated large pools of intracellular glycogen.
(18) Indirect studies based upon inhibitors, degradation products, and microinjected antibodies have suggested that the IDE can initiate cellular insulin degradation in mammalian cells.
(19) To further localize the site of IDE action, the fate of insulin after receptor binding was examined.
(20) In her book "Vårdandets Ide" the Finnish nurse, Katie Eriksson puts forward the thesis, that all kind af caring activities do have a common core.
Idle
Definition:
(superl.) Of no account; useless; vain; trifling; unprofitable; thoughtless; silly; barren.
(superl.) Not called into active service; not turned to appropriate use; unemployed; as, idle hours.
(superl.) Not employed; unoccupied with business; inactive; doing nothing; as, idle workmen.
(superl.) Given rest and ease; averse to labor or employment; lazy; slothful; as, an idle fellow.
(superl.) Light-headed; foolish.
(v. i.) To lose or spend time in inaction, or without being employed in business.
(v. t.) To spend in idleness; to waste; to consume; -- often followed by away; as, to idle away an hour a day.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Eager to show I was a good student, the next time we had sex, I noticed that one of my hands was, indeed, lying idle – and started to pat him on the back, absently, as if trying to wind a baby.
(3) And imagine he then found that, far from acting swiftly to capture, arrest and charge him, the Metropolitan police force (who knew something about his activities) initially stood idly by as his list of victims grew and grew.
(4) The balance is fragile and the threat of a spiral of decline is not an idle one.
(5) The KBS hypothesis of autism is not simply an idle exercise.
(6) "There are idle MPs with no outside interests and there are fantastic public servants that do have them."
(7) On Saturday an idle digg ing machine signalled the hasty clearing of the building site to make way for the refugees, who have fled from countries including Syria and Eritrea .
(8) In circumstances in which energy conversion rate and supplies of reducing power exceed the capacity of the biosynthetic machinery, energy-dependent H2 production presumably represents a regulatory device that facilitates "energy-idling."
(9) Relative to EM, Meritec had the highest specificity (97%), followed by Virogen (95%), IDL (91%), Pathfinder (85%), Behring (81%), Bartels (72%), and Rotazyme (71%).
(10) Thus, introducing fish oil into an atherogenic diet reduced the number of VLDL, IDL and LDL particles in plasma by as much as 50%, reduced the cholesteryl ester content of the circulating lipoprotein, and reduced the ability of the VLDL to stimulate cholesterol esterification in macrophages.
(11) 12.44am BST Ah, here's @NotCoachTito, sitting somewhere idly wondering what it's like in Fenway tonight...actually, he may have a decent idea of the atmosphere.
(12) It was on the set of The Frost Report that production staff began to refer to Barker and Corbett as "the two Ronnies", while the writing team included Michael Palin, Terry Jones, Graham Chapman, and Eric Idle – every Monty Python member bar Terry Gilliam – as well as Marty Feldman and lead writer Antony Jay, who went on to create Yes, Minister.
(13) Moreover, a larger fraction of plasma VLDL is transformed into IDL and LDL, the latter representing the main plasma cholesterol carrier.
(14) Hagere Selam remains a modest place of mudwalled shops with corrugated roofs, cows, donkeys and sheep wandering unpaved streets and children idling away an afternoon at table football – a generation with no memory of the famine that killed hundreds of thousands and woke up the world.
(15) Epidemiological studies in humans suggest that IDL or remnant lipoproteins are predictors of the severity or progression of atherosclerosis.
(16) It would be idle to pretend that Cameron doesn't have talents as a leader.
(17) A chlorine sanitizer was circulated (5 min, 40 degrees C) and the unit containing sanitizing solution left idle overnight.
(18) Facebook Twitter Pinterest Either way, I love Jane for idly sticking two fingers up at the idea of a spa break in Rhodes or other emblems of “sophistication” being the only thing to aspire to.
(19) Bidders have spent an estimated £1m each on their bids but, according to one industry source, the process has stalled and franchise owners are being forced to retain expensive but idle bidding teams.
(20) The results indicate that a simple depletion of his-tRNA is not sufficient to elicit the response and suggest that idle ribosomes are required for regulation.