(1) Moreover, one possible mechanism of intracellular insulin degradation is that cell surface IDE may be internalized with the insulin receptor complex and may degrade insulin during the intracellular process.
(2) These results demonstrate that the IDE is evolutionarily conserved and that its expression is tightly regulated during differentiation of Drosophila.
(3) A ventrally localized melanization inhibiting factor (MIF) has been suggested to play an important role in the establishment of the dorsal-ventral pigment pattern in Xenopus laevis [Fukuzawa and Ide:Dev.
(4) The addition of NADPH to the membranes was shown to result in the conversion of inactive protochlorophyll (ide) absorbing at about 630 nm into a form(s) with light-absorption maxima at about 640 and 652 nm, both of which disappear when chlorophyll (ide) is formed on illumination.
(5) When IDE particles are injected intravenously, the Kupffer cells of the hepatic sinusoids accumulate particles within 10 to 20 minutes, after which the clearance and excretion of IDE takes place.
(6) On the other hand the lingual IDE withdraw from the cell cycle before the corresponding labial cells.
(7) Immunoblotting experiments demonstrate that this inhibition is mediated by the reactivity of these mAbs with a 110 kDa protein, the known M(r) of IDE.
(8) A stereospecific high-performance liquid chromatographic method for the determination of (R,S)-flecainide acetate [(R,S)-N-(2-piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzam ide acetate] in human plasma and urine is described.
(9) A rapid, sensitive high-performance liquid chromatographic method has been developed for the determination of desmosine (DES) and isodesmosine (IDE), the specific cross-linking amino acids of elastin, in the tissue hydrolysates of rats.
(10) Two minutes after injection, intra- and extracellular IDE particles were found in the red pulp of the spleen.
(11) An insulin-degrading enzyme (IDE) was purified from the cytosol of human erythrocytes via the use of ammonium sulfate precipitation and chromatography on columns composed of DEAE-Sephadex, pentylagarose, hydroxylapatite, chromatofocusing resins, and Ultrogel AcA-34.
(12) Since some of these peptides have insulin-like properties, amino acid analysis of these products may enable us to identify not only the splitting position of insulin by IDE but also the site of the hormone for receptor binding.
(13) A fully automated readout unit for the BG-8 blood-grouping machine, printing Idee identification numbers with matching ABO grouping and rhesus (D) typing results is described.
(14) In vitro incubation experiments confirmed that human PMNs ingest IDE particles.
(15) The relaxant effect of cromakalim (BRL 34915), pinacidil and RP 49356 (N-methyl-2-(3-pyridyl)-tetrahydro-thiopyran-2-carbothioamide-1-ox ide) on the sustained contractions induced by 20 mM KCl were compared with the effects of nicorandil.
(16) [4R,(2E,5E)]-3-Hydroxy-2,4,6-trimethyl-2,5,7-octatriene-4-thiol ide, C11H14O2S, Mr = 210.30, hexagonal, P6(5), a = b = 9.8514 (6), c = 19.954 (1) A, V = 1677.1 A3, Z = 6, Dx = 1.249 g cm-3, lambda(Cu K alpha) = 1.5418 A, u = 23.07 cm-1, F(000) = 672, T = 298 K, R = 0.028 for 1021 unique reflections [Fo2 greater than 2 sigma(Fo2)].
(17) Row III IDE cells are also devoid of organelles related to secretory protein synthesis, although these IDE cells accumulated large pools of intracellular glycogen.
(18) Indirect studies based upon inhibitors, degradation products, and microinjected antibodies have suggested that the IDE can initiate cellular insulin degradation in mammalian cells.
(19) To further localize the site of IDE action, the fate of insulin after receptor binding was examined.
(20) In her book "Vårdandets Ide" the Finnish nurse, Katie Eriksson puts forward the thesis, that all kind af caring activities do have a common core.
Ode
Definition:
(n.) A short poetical composition proper to be set to music or sung; a lyric poem; esp., now, a poem characterized by sustained noble sentiment and appropriate dignity of style.
Example Sentences:
(1) And here they are, giving a certain Irish ode the treatment it deserves.
(2) Here, we introduce a new method to find an ODE which models both the short time and the long time dynamics.
(3) In extensive metabolizers, the drug undergoes extensive first-pass metabolism to form the active metabolites O-desmethylencainide (ODE) and 3-methoxy-O-desmethylencainide (MODE).
(4) Despite the increase in ODE AUC, no significant effect on the surface electrocardiogram 2 hours after dose administration could be detected.
(5) The classically described signs of early ODE were almost always absent.
(6) However, since plasma concentrations of the active metabolite ODE were correspondingly lower, specific encainide dosing instructions for patients with hepatic impairment are not indicated.
(7) In the ODE cells, abundant labyrinthine canals appeared in the cytoplasm, and capillary vessels were found close to the outer surface of the ODE cells.
(8) McFadden, a pop star himself, is in the news this week after his new single "Just The Way You Are (Drunk at the Bar)", released by Universal Music, was roundly read as a catchy ode to date rape.
(9) We haven't had so much as a team line-up on this broadcast to date, so I'm not holding out much hope of ODing on information about replacements.
(10) An ode to better days: Facebook Twitter Pinterest Share Share this post Facebook Twitter Pinterest close 12.30am BST Amy Poehler confirms that she and Tina Fey will discuss whether they want to host the Golden Globes tonight.
(11) Serial studies of fundus changes at frequent intervals, by routine ophthalmoscopy, steroscopic color photography, and fluorescein angiography, revealed that swelling of the optic disc was the first sign of ODE.
(12) Small differences are found among the variants in the pH range 7.5-8.2, where A and B show a "peak and trough," while A-, "Ijebu-Ode," and "Ita-Bale" exhibit a plateau.
(13) Plasma encainide, ODE and 3-methoxy-O-demethyl concentrations were similar to those observed in normal subjects who had received twice the dose of encainide, and steady-state apparent oral clearance of encainide was reduced by 66% with renal impairment.
(14) We have obtained complete A-type sequences coding for functional units Ode and Odf; consequently a total of three such unit sequences are now known from a single subunit of one molluscan hemocyanin.
(15) After the jet-black high school satire Heathers pulled the rug out from under John Hughes and his oversharing Brat Pack, in 1989, American adolescents were left with few offerings, most of them wistful odes to another age – either stylistically, as with the overblown, pirate-radio-themed Christian Slater vehicle Pump Up the Volume; or quite literally, in the case of Richard Linklater’s nostalgia-fuelled 70s pastiche, Dazed and Confused.
(16) Encainide (ENC) and its metabolites O-demethylencainide (ODE), 3-methoxy-O-demethylencainide (MODE), N-demethylencainide (NDE) and bis-N,O-demethylencainide (NODE) have been measured by two HPLC procedures.
(17) The second model is described by an ODE for which an explicit solution was obtained, and which yields the pancreatic responsivity parameters phi 1 and phi 2.
(18) The 8-h urinary metabolic profiles of encainide and its oxidized metabolites, O-desmethyl- (ODE), 3-methoxy-O-desmethyl- (MODE), N-desmethyl- (NDE) and N, O-didesmethyl- (DDE) encainide were studied in a group of 112 normal Caucasians.
(19) Encainide, ODE, or MODE was then infused in loading and maintenance doses to achieve QRS widening of 20% to 50%.
(20) Facebook Twitter Pinterest Banksy’s now Perspex-covered ode to fellow graffiti artist Tox on Jeffreys Street, London.