(1) Moreover, one possible mechanism of intracellular insulin degradation is that cell surface IDE may be internalized with the insulin receptor complex and may degrade insulin during the intracellular process.
(2) These results demonstrate that the IDE is evolutionarily conserved and that its expression is tightly regulated during differentiation of Drosophila.
(3) A ventrally localized melanization inhibiting factor (MIF) has been suggested to play an important role in the establishment of the dorsal-ventral pigment pattern in Xenopus laevis [Fukuzawa and Ide:Dev.
(4) The addition of NADPH to the membranes was shown to result in the conversion of inactive protochlorophyll (ide) absorbing at about 630 nm into a form(s) with light-absorption maxima at about 640 and 652 nm, both of which disappear when chlorophyll (ide) is formed on illumination.
(5) When IDE particles are injected intravenously, the Kupffer cells of the hepatic sinusoids accumulate particles within 10 to 20 minutes, after which the clearance and excretion of IDE takes place.
(6) On the other hand the lingual IDE withdraw from the cell cycle before the corresponding labial cells.
(7) Immunoblotting experiments demonstrate that this inhibition is mediated by the reactivity of these mAbs with a 110 kDa protein, the known M(r) of IDE.
(8) A stereospecific high-performance liquid chromatographic method for the determination of (R,S)-flecainide acetate [(R,S)-N-(2-piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzam ide acetate] in human plasma and urine is described.
(9) A rapid, sensitive high-performance liquid chromatographic method has been developed for the determination of desmosine (DES) and isodesmosine (IDE), the specific cross-linking amino acids of elastin, in the tissue hydrolysates of rats.
(10) Two minutes after injection, intra- and extracellular IDE particles were found in the red pulp of the spleen.
(11) An insulin-degrading enzyme (IDE) was purified from the cytosol of human erythrocytes via the use of ammonium sulfate precipitation and chromatography on columns composed of DEAE-Sephadex, pentylagarose, hydroxylapatite, chromatofocusing resins, and Ultrogel AcA-34.
(12) Since some of these peptides have insulin-like properties, amino acid analysis of these products may enable us to identify not only the splitting position of insulin by IDE but also the site of the hormone for receptor binding.
(13) A fully automated readout unit for the BG-8 blood-grouping machine, printing Idee identification numbers with matching ABO grouping and rhesus (D) typing results is described.
(14) In vitro incubation experiments confirmed that human PMNs ingest IDE particles.
(15) The relaxant effect of cromakalim (BRL 34915), pinacidil and RP 49356 (N-methyl-2-(3-pyridyl)-tetrahydro-thiopyran-2-carbothioamide-1-ox ide) on the sustained contractions induced by 20 mM KCl were compared with the effects of nicorandil.
(16) [4R,(2E,5E)]-3-Hydroxy-2,4,6-trimethyl-2,5,7-octatriene-4-thiol ide, C11H14O2S, Mr = 210.30, hexagonal, P6(5), a = b = 9.8514 (6), c = 19.954 (1) A, V = 1677.1 A3, Z = 6, Dx = 1.249 g cm-3, lambda(Cu K alpha) = 1.5418 A, u = 23.07 cm-1, F(000) = 672, T = 298 K, R = 0.028 for 1021 unique reflections [Fo2 greater than 2 sigma(Fo2)].
(17) Row III IDE cells are also devoid of organelles related to secretory protein synthesis, although these IDE cells accumulated large pools of intracellular glycogen.
(18) Indirect studies based upon inhibitors, degradation products, and microinjected antibodies have suggested that the IDE can initiate cellular insulin degradation in mammalian cells.
(19) To further localize the site of IDE action, the fate of insulin after receptor binding was examined.
(20) In her book "Vårdandets Ide" the Finnish nurse, Katie Eriksson puts forward the thesis, that all kind af caring activities do have a common core.
Tide
Definition:
(prep.) Time; period; season.
(prep.) The alternate rising and falling of the waters of the ocean, and of bays, rivers, etc., connected therewith. The tide ebbs and flows twice in each lunar day, or the space of a little more than twenty-four hours. It is occasioned by the attraction of the sun and moon (the influence of the latter being three times that of the former), acting unequally on the waters in different parts of the earth, thus disturbing their equilibrium. A high tide upon one side of the earth is accompanied by a high tide upon the opposite side. Hence, when the sun and moon are in conjunction or opposition, as at new moon and full moon, their action is such as to produce a greater than the usual tide, called the spring tide, as represented in the cut. When the moon is in the first or third quarter, the sun's attraction in part counteracts the effect of the moon's attraction, thus producing under the moon a smaller tide than usual, called the neap tide.
(prep.) A stream; current; flood; as, a tide of blood.
(prep.) Tendency or direction of causes, influences, or events; course; current.
(prep.) Violent confluence.
(prep.) The period of twelve hours.
(v. t.) To cause to float with the tide; to drive or carry with the tide or stream.
(n.) To betide; to happen.
(n.) To pour a tide or flood.
(n.) To work into or out of a river or harbor by drifting with the tide and anchoring when it becomes adverse.
Example Sentences:
(1) "So we do what we can to keep the red tide from drowning us.
(2) For the moment, the priority is managing this endless human tide.
(3) Government ministers and officials are distressed that the home secretary's resignation has failed to stem the tide of fresh allegation and counter allegation between the protaganists and a number of potentially damaging questions still hang over the visa affair.
(4) First, the argument that balanced budgets and economic growth inevitably lead to a fairer society because “all boats rise on a rising tide”.
(5) The home side dominated the opening quarter of an hour as Argentina struggled to find their feet but the tide turned when Di Maria curled a right-footed shot past Claudio Bravo for the equaliser 10 minutes later.
(6) Updated at 12.27pm GMT 11.46am GMT There's debate at Chesil Beach over when exactly high tide is, writes Steven Morris.
(7) It soon became a standard text for aspiring Young Conservatives and Bow Groupers in the days before the Thatcherite tide had engulfed even those institutions.
(8) In the debate, Sturgeon clearly signalled she was open to working with Ed Miliband, at one point saying: “I agree with Ed.” She challenged the Labour leader to join her in seeking an end austerity and said the SNP was his “ally” in trying to roll back a tide of privatisation in the NHS.
(9) Governments must defeat a rising tide of protectionism to prevent a further slowdown in global growth, the head of the International Monetary Fund has said.
(10) Tony Abbott has tried to stem the tide of discontent within his own party ranks, defending his decision to award a knighthood to Prince Philip and saying the government is “strong and effective” under his leadership.
(11) Apparently the sea wall is a favourite base for extravagant jumps into the water, but not at low tide.
(12) While those "close relation[s]" are not supposed to be passed on for watchlisting absent other "derogatory information", their data may be retained within TIDE for unspecified "analytic purposes".
(13) Tamerlan Tsarnaev was entered into a central database of potential terrorists, the Terrorist Identities Datamart Environment (Tide), that is maintained by the National Counterterrorism Center.
(14) Donald Trump is fairly progressive about gay people but when you look at Mike Pence and the Republican party, the religious undertone threatens to roll back the tide of progress.
(15) The lack of obvious motive baffled commentators who said the British director of Top Gun, Crimson Tide and Beverly Hills Cop II appeared to have it all: success, wealth, respect, a wife and two young children.
(16) We have not turned the tide on the ease with which money can be shifted out of developing countries.” There are lots of ways to get money out of a country undetected but the easiest is through trade misinvoicing, which is the overpricing of imports and the underpricing of exports – and accounts for 77% of all illicit financial flows.
(17) We are up against a very strong king tide so some of the floodwater will take time to recede.” New Zealand prime minister Bill English addressed the situation on social media on Saturday.
(18) Outbreaks of airborne respiratory irritation in populations exposed to red tides may be the most common public health problem associated with red tides.
(19) While it is still ridiculous to suggest that Boko Haram will be defeated in six weeks, and still far too early to conclude that the tide has turned against the Islamist group, it is reasonable to think that the international intervention may free up some Nigerian military resources in time for the rescheduled election; and, more importantly, keep Boko Haram occupied while voting takes place.
(20) But hard lobbying from the South African government and its regional partners turned the tide for Dlamini-Zuma.