(1) Further analysis with two other synthetic peptides (212Cys to 222Glu and Cys X 221Ile to 236Glu) indicated that the dodecapeptide Ile-Glu-Phe-Gln-Lys-Asn-Asn-Arg-Leu-Leu-Glu mimicked either the whole or a major part of the neutralization epitope.
(2) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(3) The commercially available chromogenic p-nitroanilide substrates Pro-Phe-Arg-NH-Np (S2302 or chromozym PK), Glp-Pro-Arg-NH-Np (S2366), Ile-Glu-(piperidyl)-Gly-Arg-NH-Np (S2337), and Ile-Glu-Gly-Arg-NH-Np (S2222) were tested for their suitability as substrates in these assays.
(4) We have named them bombolitin I (Ile-Lys-Ile-Thr-Thr-Met-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin II (Ser-Lys-Ile-Thr-Asp-Ile-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin III (Ile-Lys-Ile-Met-Asp-Ile-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin IV (Ile-Asn-Ile-Lys-Asp-Ile-Leu-Ala-Lys-Leu-Val-Lys-Val-Leu-Gly-His-Val-NH2 ), and bombolitin V (Ile-Asn-Val-Leu-Gly-Ile-Leu-Gly-Leu-Leu-Gly-Lys-Ala-Leu-Ser-His-Leu-NH2 ).
(5) Ile-tRNA synthetase shows little inactivation in either process.
(6) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(7) The minimal length for an effective substrate has been characterised as an octapeptide sequence derived from the amino terminal portion of angiotensinogen (residues 6----13): His-Pro-Phe-His-Leu-Val-Ile-His (Leu-Val is the scissile bond).
(8) The lipid-mobilizing activity of a synthetic peptide, NH2-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-COOH, corresponding to the 31-44 amino-acid sequence of human growth hormone, was studied.
(9) The structures of two crystal forms of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe have been determined.
(10) The alpha His58(E7) to Gly and Val62(E11) to Ala substitutions caused 80- and 3-fold increases, respectively, in k'CO for T-state alpha subunits, and the alpha Val62(E11) to Ile mutation caused a 3-fold decrease.
(11) Resonances from several amino acids including His 16, Gly 24, Ile 48, and Met 61 experience strong ring-current shifts due to their placement near the heme.
(12) The terminal sequences are: NH2-Ile-Val-Gly-Gly-Ile-Asp.....Gly-Lys-Tyr-Pro-Tyr-Gln-Val-Ser-Leu-Arg-COOH.
(13) Peptide mapping and amino acid sequence analyses have revealed that Val-406 of IgG1 carrying allotype a is substituted for Ile in the case of allotype j. X-ray crystallographic data indicate that Met-398 is in close spatial proximity to Val (Ile)-406.
(14) Site-directed mutation of codon 203 and transient expression of these cDNA in COS-7 cells indicated that Phe, Ile, Leu, and Val permit transmembrane expression, whereas Ser, Thr, Tyr, Asn, Gly, Ala, Asp and Lys enable phosphatidylinositol-glycan attachment.
(15) The N-terminal amino acid sequence of this sialidase, Ala-Asp-X-Ile-Phe-Val-Arg-Glu-Thr-Arg-Ile-Pro-, was determined.
(16) Supplementation of the low protein diet with a synthetic mixture of branched-chain AA (Val, Leu and Ile) normalized the plasma levels of these AA.
(17) They correspond to the sequence from Leu-149 to Ile-162.
(18) The N5 atom of flavin interacts with the amide NH of Ile 59 in A.
(19) Chymotrypsin cleavage of this peptide resulted in a single-labeled fragment with the sequence: Glu-Val-Ala-Asn-(Pyridoxal-P-Lys)-Val-Gly-Gly-Ile-Tyr.
(20) Both sarcosine-isoleucine-angiotensin II ([Sar, Ile]-ANG II) and atropine blocked, and nadolol increased, the effect of EFS and exogenous angiotensin II on serotonin production.
Tile
Definition:
(v. t.) To protect from the intrusion of the uninitiated; as, to tile a Masonic lodge.
(n.) A plate, or thin piece, of baked clay, used for covering the roofs of buildings, for floors, for drains, and often for ornamental mantel works.
(n.) A small slab of marble or other material used for flooring.
(n.) A plate of metal used for roofing.
(n.) A small, flat piece of dried earth or earthenware, used to cover vessels in which metals are fused.
(n.) A draintile.
(n.) A stiff hat.
(v. t.) To cover with tiles; as, to tile a house.
(v. t.) Fig.: To cover, as if with tiles.
Example Sentences:
(1) Inside, the tiles and the stained glass are said to be perfection, matched against murals that depict the inventions of the industrial revolution and the signing of the Magna Carta.
(2) The risk of getting malaria was greater for inhabitants of the poorest type of house construction (incomplete, mud, or cadjan (palm) walls, and cadjan thatched roofs) compared to houses with complete brick and plaster walls and tiled roofs.
(3) The artist covered every inch of the steps in front of his house in tiles, ceramics and mirrors – originally in the green, yellow, blue and white of the Brazilian flag, later adding tiles in other colours brought by visitors.
(4) The infected cells treated by this method showed light green fluorescence of the protoplasm, with a dark nucleus, while the intact cells had tile-red cytoplasm.
(5) The results of these experiments demonstrated a significant superiority of this modification over the conventional techniques, particularly over the tile technique used generally in this country.
(6) The rustic rooms have clay tiles and wooden furniture, and the walls are brightened up with local fabrics.
(7) The algorithm presented has been developed to choose the tiling which minimizes the estimated error when the tile approximation of the surface is used in subsequent quantitative algorithm such as the calculation of surface area.
(8) When General Electric jobs left Schenectady so did a way of life Read more Patrignani proudly chats me through the bewildering array of silicone-based products Momentive makes and that end up in everything from lipstick, car parts and the adhesives that are used in stamps and bandages to airplane seats and the glue that held the tiles on the space shuttle.
(9) Any of the original N2 fields or composites of M adjacent tiles can be recalled to the video display for analysis.
(10) "There's so much graphic detail in some of the tiles that they seem to speak with a modern voice," adds Roberts.
(11) Tritium retention noted in graphite tiles underscores the significance of material selection in present and future 3H-fueled fusion devices.
(12) The efficacy of defibrillation using the damped sine and constant-tile (60%) truncated exponential waveforms was determined in each of nine dogs.
(13) The Glasgow Boys went after this mood with a will and set up temporary homes among the red-tiled roofs of the rural east – Cockburnspath was by no means their only base – to prospect for scenes that would do justice to an imagination fired by their heroes Corot , Millet and Bastien-Lepage.
(14) The genius of The Great British Bake Off Read more Viewers have seen contestants throw pots blindfolded, and create objects ranging from bone china chandeliers to decorated tiles and bathroom sinks.
(15) The tiles, I am told, are also Italian, the chandeliers Czech, the fridge American, the stove German.
(16) Ceramic samples such as tiles and bricks were collected from locations between 523 and 2,453 m from the hypocenter in Hiroshima and from between 731 and 1,565 m in Nagasaki.
(17) At that time X----- itself was untouched by shot and shell, the old houses in the square with their quaint red-tiled roofs, irregular as peaks of a sierra, and their higgledy-piggledy doors and windows, were as yet intact.
(18) Centro Cerámica Triana Facebook Twitter Pinterest Photograph: Alamy Housed in an old ceramics factory built on the site of a 16th-century one, inevitably plonked on a Roman one, this museum (€2pp, Calle Antillano Campos 14) could do more to trumpet the industry that spawned Triana, created the look and feel of Seville, and inspired Lisbon’s artisans to have a go at the whole tile thing.
(19) Pictures showed a large group of people lying on polished tiled flooring, most of them near to a wall and surrounded by rubble and other debris.
(20) 120 Grosvenor Street, 0161 273 1552, sandbarmanchester.co.uk Marble Arch The Marble Arch pub, Manchester It's 125 years old but this handsome Victorian boozer – all glazed tile work and vintage detail – has never been busier.