(a.) Contrary to good, in a physical sense; contrary or opposed to advantage, happiness, etc.; bad; evil; unfortunate; disagreeable; unfavorable.
(a.) Contrary to good, in a moral sense; evil; wicked; wrong; iniquitious; naughtly; bad; improper.
(a.) Sick; indisposed; unwell; diseased; disordered; as, ill of a fever.
(a.) Not according with rule, fitness, or propriety; incorrect; rude; unpolished; inelegant.
(n.) Whatever annoys or impairs happiness, or prevents success; evil of any kind; misfortune; calamity; disease; pain; as, the ills of humanity.
(n.) Whatever is contrary to good, in a moral sense; wickedness; depravity; iniquity; wrong; evil.
(adv.) In a ill manner; badly; weakly.
Example Sentences:
(1) Thirteen patients with bipolar affective illness who had received lithium therapy for 1-5 years were tested retrospectively for evidence of cortical dysfunction.
(2) Anti-corruption campaigners have already trooped past the €18.9m mansion on Rue de La Baume, bought in 2007 in the name of two Bongo children, then 13 and 16, and other relatives, in what some call Paris's "ill-gotten gains" walking tour.
(3) The patients should have received treatment for at least seven days and they should not be "ill".
(4) Acceptance of less than ideal donors is ill-advised even though rejection of such donors conflicts with the current shortage of organs.
(5) Patients were chronically ill homosexual men with multiple systemic opportunistic infections.
(6) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
(7) However, survival was closely related to the severity of the illness at the time of randomization and was not altered by shunting.
(8) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.
(9) Another important factor, however, seems to be that patients, their families, doctors and employers estimate capacity of performance on account of the specific illness, thus calling for intensified efforts toward rehabilitation.
(10) It ignores the reduction in the wider, non-NHS cost of adult mental illness such as benefit payments and forgone tax, calculated by the LSE report as £28bn a year.
(11) Several dimensions of the outcome of 86 schizophrenic patients were recorded 1 year after discharge from inpatient index-treatment to complete a prospective study concerning the course of illness (rehospitalization, symptoms, employment and social contacts).
(12) The cyclical nature of pyromania has parallels in cycles of reform in standards of civil commitment (Livermore, Malmquist & Meehl, 1958; Dershowitz, 1974), in the use of physical therapies and medications (Tourney, 1967; Mora, 1974), in treatment of the chronically mentally ill (Deutsch, 1949; Morrissey & Goldman, 1984), and in institutional practices (Treffert, 1967; Morrissey, Goldman & Klerman (1980).
(13) In South Africa, health risks associated with exposure to toxic waste sites need to be viewed in the context of current community health concerns, competing causes of disease and ill-health, and the relative lack of knowledge about environmental contamination and associated health effects.
(14) The move comes as a poll found that 74% of people want doctors to be allowed to help terminally ill people end their lives.
(15) The start of clinical illness was the 5th month of life.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) Bipolar affective illness were more frequent in the families of bipolar than unipolar probands.
(18) This paper describes the demographic, clinical, and psychosocial characteristics of a sample of chronically mentally ill clients at a large comprehensive community mental health center.
(19) Cholecystectomy provided successful treatment in three of the four patients but the fourth was too ill to undergo an operation; in general, definitive treatment is cholecystectomy, together with excision of the fistulous tract if this takes a direct path through the abdominal wall from the gallbladder, or curettage if the course is devious.
(20) Whenever you are ill and a medicine is prescribed for you and you take the medicine until balance is achieved in you and then you put that medicine down.” Farrakhan does not dismiss the doctrine of the past, but believes it is no longer appropriate for the present.
Phencyclidine
Definition:
Example Sentences:
(1) To test the hypothesis that EAA agonists are involved in transmission of nociceptive information in the spinal cord, we tested the effect of various opioid, sigma and phencyclidine compounds on the action of NMDA in the tail-flick, hot-plate and biting and scratching nociceptive tests.
(2) The increase probably reflects an inhibition of the re-uptake of released 3H-noradrenaline; in addition, phencyclidine appears to enhance the release of noradrenaline per pulse.--The actions of phencyclidine and ketamine on central noradrenergic neurones may contribute to the characteristic psychotropic side-effects of these general anaesthetics.
(3) The present experiments compared the noncompetitive N-methyl-D-aspartate antagonists phencyclidine and MK-801 with the anticonvulsant phenytoin in a model of focal brain ischemia.
(4) The neuronal localization of glutamate and phencyclidine (PCP) receptors was evaluated in the cerebral cortex and hippocampal formation of rat CNS using quantitative autoradiography.
(5) Emergency Room patients at Riverside General Hospital who are found by the attending physician to have depressed sensorium and altered personality are routinely subjected to urine tests for various drugs of abuse including phencyclidine (PCP).
(6) Phencyclidine (PCP) is a dissociative anesthetic agent which blocks the excitatory effect of N-methyl-D-aspartate (NMDA) in the central nervous system.
(7) Only the sigma agonist, phencyclidine, showed any capacity for blocking the PTZ stimulus.
(8) Drugs of the fentanyl series (4-anilino-piperidines) were potent displacers whereas agonists of the delta- (enkephalin derivatives), sigma- (phencyclidine, haloperidol, 3-hydroxyphenyl-propylpiperidine) or K- (U 50488) opiate sites had a low affinity (Ki greater than 0.5 microM) for 3H-lofentanil specific binding sites.
(9) Related compounds including [D-Ala2, D-Leu5]enkephalin (DADLE), n-allylnormetazocine and phencyclidine were also examined.
(10) Phencyclidine residues were found in the brains of rat pups of mothers dosed with this drug during pregnancy.
(11) For 15 unselected urines the concentrations of phencyclidine showed no significant correlation with urinary pH.
(12) However, at high doses, DTG selectively suppressed the potentiation induced by a low dose of DTG and reduced the NMDA response below base line, presumably due to its low affinity for phencyclidine sites.
(13) Phencyclidine, which is an indirect dopaminergic agonist in the caudate, caused inhibition of the discharges of caudate neurons resembling that induced by dopamine itself.
(14) Significantly more blunting of the response of TSH to TRH was shown in cocaine and phencyclidine abusers compared with that seen in controls.
(15) Recently, we reported the characterization of a selective sigma receptor ligand, 1,3-di-o-tolyl-guanidine (DTG), that shows negligible crossreactivity with phencyclidine receptors.
(16) Phencyclidine had a biphasic effect on overall response rates in both components: response rates increased and then decreased as the dose was increased.
(17) The effects of phencyclidine infusions on fixed-ratio responding were variable.
(18) One of the analogs, cis-2-hydroxymethyl-r-1-(N-piperidyl)-1-(2-thienyl) cyclohexane (5) was found to show a high affinity (IC50 = 16 nM) for the phencyclidine (PCP) binding sites, very close to that of TCP, and to be 38-fold more potent in binding than its trans isomer.
(19) In animals sedated with phencyclidine or ketamine the only significant difference detected was in the mean cell volume.
(20) [3H]N-1-(2-Thienyl)cyclohexyl-3,4-piperidine binding to the phencyclidine site associated with the N-methyl-D-aspartate receptor was reduced by 60-80% in all brain regions examined (P less than 0.001).