(n.) A compound with, or derivative of, the imido group; specif., a compound of one or more acid radicals with the imido group, or with a monamine; hence, also, a derivative of ammonia, in which two atoms of hydrogen have been replaced by divalent basic or acid radicals; -- frequently used as a combining form; as, succinimide.
Example Sentences:
(1) An analysis of the copper absorption observed with the oxidized enzyme and a comparison with that for Cu(II)(imid)4 suggests that the copper is not simply ligated to four imidazoles.
(2) Comparative studies on the biodegradability of amides and imides are presented.
(3) Deamidation of Asn residues can occur either by direct hydrolysis of the Asn residue or via a cyclic imide intermediate.
(4) This inhibition was not observed when 5'-adenosine(beta, gamma-imide) triphosphate blocks inhibition by ATP.
(5) In contrast, the equilibrium and kinetic properties of proline imide bond isomerization, believed to be involved in the slow folding reactions, are largely independent of pH.
(6) All the other drugs enhanced aggressive behaviour to varying degrees but proved to be less potent than IMID in inducing mounting, and clonidine reduced mounting at all the doses tested.
(7) Carbodi-imide inhibited the cellulase, and kinetic analysis indicated that there was an average of 1 mol of carbodi-imide binding to the cellulase during inactivation.
(8) This study also highlights the importance of internal cross-link formation, which can occur by intramolecular nucleophilic attack, a process that has often been overlooked by investigators employing carbodi-imide modification of carboxylate groups in proteins.
(9) A chemiluminescent aryl acridinium ester was synthesized which possesses an imidate ester group capable of reacting with proteins under mild conditions.
(10) The haem group was identified as a site of reaction with the carbodi-imide, and is as a consequence covalently linked to the peptide by a bond in addition to the thioether bonds normally present.
(11) Naphthylhydrazides and arylhydrazides, used as the labels, were incorporated via their imidate or their succinimide esters.
(12) Analysis of the mass spectra of many of these showed that three side reactions can occur: (1) methylation of the imide carbonyl group; (2) addition of methanol or water to the vinyl substituent; (3) transmethylation of the ethoxycarbonyl group.
(13) A water-soluble carbodi-imide [1-cyclohexyl-3-(2-morpholinoethyl)carbodi-imide methotoluene-p-sulphonate], referred to as carbodi-imide reagent, and glycine methyl ester were used to modify the free carboxyl groups of the membrane.
(14) Inhibitors of lysosomal acidification (4,4'-di-isothiocyanostilbene-2,2'-disulphonate, NN'-dicyclohexylcarbodi-imide, carbonyl cyanide m-chlorophenylhydrazone, NH4Cl and methylamine hydrochloride) did not alter cystine egress or countertransport in polymorphonuclear-leucocyte lysosome-rich granular fractions at pH 7.0.
(15) It is concluded that dicyclohexylcarbodi-imide inhibits mitochondrial oxidative phosphorylation by reacting covalently with a group on this chloroform-methanol-soluble protein.
(16) The structure of the pigment has been studied by chromate degradation followed by identification of the imide products by thin-layer chromatography.
(17) Both INDO and IMID improved effective hepatic blood flow in the septic animals to virtually sham, nonseptic levels without significantly altering systemic hemodynamics.
(18) Their solution stability was shown to be compromised compared to 3-methylglutarimide (3-MG) and other imides.
(19) the cross-linked complexes can be split at the band originating from the imidate group by treatment with ammonia.
(20) An amide bond was first formed between the free carboxy group of the retinoid and a primary amino group of aminohexyl-Sepharose 4B, by reaction with carbodi-imide, and the ester group of the resin-bound retinoid was then hydrolysed in an alkaline medium.
Nitrogen
Definition:
(n.) A colorless nonmetallic element, tasteless and odorless, comprising four fifths of the atmosphere by volume. It is chemically very inert in the free state, and as such is incapable of supporting life (hence the name azote still used by French chemists); but it forms many important compounds, as ammonia, nitric acid, the cyanides, etc, and is a constituent of all organized living tissues, animal or vegetable. Symbol N. Atomic weight 14. It was formerly regarded as a permanent noncondensible gas, but was liquefied in 1877 by Cailletet of Paris, and Pictet of Geneva.
Example Sentences:
(1) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
(2) The measurement of the intestinal metabolism of the nitrogen moiety of glutamic acid has been investigated by oral ingestion of l-[15N]glutamic acid and sampling of arterialized blood.
(3) The induction of cells with two Y chromosomes by nitrogen mustard (NM) was examined.
(4) The disappearance of the herbicide, Avadex (40% diallate), from five agricultural soils (differing in either pH, carbon content, or nitrogen content), incubated under sterile and non-sterile conditions, was followed for a period of 20 weeks.
(5) Suspensions of isolated insect flight muscle thick filaments were embedded in layers of vitreous ice and visualized in the electron microscope under liquid nitrogen conditions.
(6) Airway closure (CV), functional residual capacity (FRC) and the distribution of inspired gas (nitrogen washout delay percentage, NWOD %) and arterial oxygen tension (PaO2) was measured by standard electrodes in eight extremely obese patients before and after weight loss (mean weights 142 and 94 kg, respectively) following intestinal shunt operation.
(7) Formula fed infants retained more nitrogen and gained weight faster.
(8) Triglyceride (Trigly) in female dogs, glutamic-pyruvic transaminase (GPT) and urea nitrogen (Urea-N) in male dogs tended to increase.
(9) Nitrogen retention was curvilinear in relation to metabolic live weight (kg0.75) in both series.
(10) Corynebacterium parvum-treated mice produce large amounts of circulating nitrogen oxides and develop a severe liver injury in response to lipopolysaccharide (LPS).
(11) Eight men and eight women each performed peak oxygen intake tests on a cycle ergometer breathing ambient air and a mixture of 12% oxygen in nitrogen (equivalent to an altitude of 4400 m) in the two experiments.
(12) From this, it was suggested that a negligible amount of oestradiol was released from these compounds and that the oestradiol moiety was useful as a carrier for the nitrogen mustard moiety.
(13) The intravenous administration of ovine placental lactogen to pregnant and non-pregnant sheep produced significant acute decreases in plasma free fatty acid, glucose and amino nitrogen concentrations.
(14) In contrast, nitrogen incubation did not alter the basal levels of TBA reactants except for a small rise associated with VE deficiency.
(15) MCT TPN was found to have some disadvantages, especially with regard to nitrogen balance and plasma albumin levels.
(16) Nitrogen mustard (N2M) treatment of rabbits induced neutropenia, and, in ligated ileal loops, it inhibited fluid secretion induced by salmonella or by cholera toxin (CT).
(17) For dipeptides containing the amino terminal residues glycine, alanine and phenylalanine, abstraction of the hydrogen from the carbon adjacent to the peptide nitrogen was the major process leading to the spin-adducts.
(18) The raw data are obtained by capillary gas chromatography using a nitrogen-phosphorus detector.
(19) Total protein, RNA, DNA, nitrogen, free amino acids and water content were determined in both lymphatic organs.
(20) This is the first evidence supporting carbon-nitrogen bond formation as the initial site of interaction between the two substrate molecules.