(a.) Not separated in respect to place by anything intervening; proximate; close; as, immediate contact.
(a.) Not deferred by an interval of time; present; instant.
(a.) Acting with nothing interposed or between, or without the intervention of another object as a cause, means, or agency; acting, perceived, or produced, directly; as, an immediate cause.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
(3) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
(4) However, the presence of these two molecules was restored if testosterone was supplemented immediately after orchiectomy.
(5) Immediate postexercise two-dimensional echocardiography demonstrated exercise-induced changes in 8 (47%) patients (2 with normal and 6 with abnormal results from rest studies).
(6) Determination of plasma luteinizing hormone (LH) levels in the peripubertal female rats revealed that plasma LH was increased transiently immediately after NPY administration.
(7) 2.39pm BST The European Union called for a "thorough and immediate" investigation of the alleged chemical attack.
(8) I would immediately look askance at anyone who lacks the last and possesses the first.
(9) The results indicated that smoke, as opposed to sham puffs, significantly reduced reports of cigarette craving, and local anesthesia significantly blocked this immediate reduction in craving produced by smoke inhalation.
(10) Earlier this month, Khamenei insisted that all sanctions be lifted immediately on a deal being reached, a condition that the US State Department dismissed.
(11) The treatment was started either immediately or delayed for 48 h after peritoneal inoculation.
(12) Other recommendations for immediate action included a review of the Nursing and Midwifery Council and the General Medical Council for doctors, with possible changes to their structures; the possible transfer of powers to launch criminal prosecutions for care scandals from the Health and Safety Executive to the Care Quality Council; and a new inspection regime, which would focus more closely on how clean, safe and caring hospitals were.
(13) United believe it is more likely the right-back can be bought in the summer but are exploring what would represent the considerable coup of acquiring the 26-year-old immediately.
(14) GnRH infusion produced an immediate increase in plasma LH concentrations in the mares that ovulated during the infusion period and LH levels peaked at the time of ovulation.
(15) Release of nsP4 from P1234 appears to be independent of the other cleavages and occurs primarily immediately after translation.
(16) If Cory Bernardi wasn’t currently in a period of radio silence as he contemplates his immediate political future he’d be all over this too, mining the Trumpocalypse – or in our domestic context, mining the fertile political fault line where Coalition support intersects with One Nation support.
(17) Benzaldehyde's in cherries and cherrystones and amaretto, so it's immediately a base to pair things with."
(18) Since iron from fortified formulas is well absorbed during the first three months of life, even if it is not immediately used for hemoglobin formation, an inccrease in the iron stores will occur...
(19) The 14-fold increase in prolonged apnea frequency immediately following regurgitation supports the hypothesis for a causal relationship between apnea and regurgitation.
(20) Blood samples were collected from an antecubital vein at sea level (S1), in a base camp at 1515 m prior to the summit ascent (S2), on the summit at 3285 m after 6.5 hours of climbing (S3), at base camp immediately after the descent (S4), and at sea level following a trail descent from the base camp (S5).
Mediate
Definition:
(a.) Being between the two extremes; middle; interposed; intervening; intermediate.
(a.) Acting by means, or by an intervening cause or instrument; not direct or immediate; acting or suffering through an intervening agent or condition.
(a.) Gained or effected by a medium or condition.
(a.) To be in the middle, or between two; to intervene.
(a.) To interpose between parties, as the equal friend of each, esp. for the purpose of effecting a reconciliation or agreement; as, to mediate between nations.
(v. t.) To effect by mediation or interposition; to bring about as a mediator, instrument, or means; as, to mediate a peace.
(v. t.) To divide into two equal parts.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.