(a.) Immeasurable; unlimited. In commonest use: Very great; vast; huge.
Example Sentences:
(1) Immense amounts of data about cancer-associated chromosome aberrations have been collected during the last 10 years, and the systematic evaluation of these data has disclosed a number of correlations between chromosome change and neoplastic disease.
(2) "It's immensely frustrating and I've got to the point now where I can't do internships," he said.
(3) The referendum vote has immense political implications but no direct legal effect.
(4) Resentment towards the political elite, the widening gap between the immensely rich and the poor, the deteriorating social security system, the collapse in oil prices and what Forbes has called "a stampede" of investors out of Russia – an outflow of $42bn in the first four months of 2012 – means the economy is flagging.
(5) The strain and expense of all these moves has been immense.
(6) These questions are the points of collision of two immensely important spheres of interest in our everyday life.
(7) It's the first in our planet's history where one species - ours - has Earth's future in its hands, and could jeopardise not only itself, but life's immense potential.
(8) I would urge her to follow the example of Elizabeth I, who, on appointing as her chief minister Sir William Cecil, said of him: “This opinion I have of you: that whatever you know my personal opinion to be, you will give me advice that is best for the realm.” Valerie Crews Beckenham, Kent • Another immensely qualified person loses their job for not being optimistic enough about Brexit.
(9) After 14 years of great lovemaking, an erection causes him immense pain and has terminated our sex life.
(10) Despite the "immense challenges" which Yves Mersch cited today , BNP reckons the ECB will have to take unconventional action to fight off weak inflation and to stimulate growth.
(11) It may be just as well that Hugh Grant fervently believes a film succeeds on its qualities, not on publicity about its stars, because he did his tabloid reputation as a heartless, feather-brained Lothario immense harm in the process of delivering damning testimony on phone-hacking to the Leveson inquiry on Monday.
(12) Immense occupancy and porta hepatis proximity of the cysts were triggers for developing jaundice.
(13) An immensely cerebral man, who trained himself to need only six hours of sleep - believing that a woman should have seven and only a fool eight - Mishcon was not a man given to small talk, nor one who would tolerate prattle for the sake of it.
(14) During the last years of her life, Shearer wrote book reviews (not just of dance books) for the Daily and Sunday Telegraph, which were immensely readable though not celebrated for their generosity towards authors.
(15) Global policymakers know well the immense value of forests – so why have development interventions largely failed to harness the positive contributions of forested landscapes?
(16) Thanet suffers from immense shortages of housing and jobs.
(17) The kinds of skills graduates bring can be immensely valuable.
(18) At such levels, public outrage would be immense, but we are prepared to tolerate such risks from the climate because the prospects of catastrophic levels of warming are still regarded by many as remote, the study suggested, and we are poor at calculating risk.
(19) A case is reported in which an immense cranial vault was reduced as part of the rehabilitation of a patient with severe hydrocephalus who had preservation of the intellect.
(20) Meanwhile volumes two and three of The Gulag Archipelago appeared to less public acclaim than volume one, but confirmed the uniqueness and immensity of that vast enterprise.
Profound
Definition:
(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.