(a.) Immeasurable; unlimited. In commonest use: Very great; vast; huge.
Example Sentences:
(1) Immense amounts of data about cancer-associated chromosome aberrations have been collected during the last 10 years, and the systematic evaluation of these data has disclosed a number of correlations between chromosome change and neoplastic disease.
(2) "It's immensely frustrating and I've got to the point now where I can't do internships," he said.
(3) The referendum vote has immense political implications but no direct legal effect.
(4) Resentment towards the political elite, the widening gap between the immensely rich and the poor, the deteriorating social security system, the collapse in oil prices and what Forbes has called "a stampede" of investors out of Russia – an outflow of $42bn in the first four months of 2012 – means the economy is flagging.
(5) The strain and expense of all these moves has been immense.
(6) These questions are the points of collision of two immensely important spheres of interest in our everyday life.
(7) It's the first in our planet's history where one species - ours - has Earth's future in its hands, and could jeopardise not only itself, but life's immense potential.
(8) I would urge her to follow the example of Elizabeth I, who, on appointing as her chief minister Sir William Cecil, said of him: “This opinion I have of you: that whatever you know my personal opinion to be, you will give me advice that is best for the realm.” Valerie Crews Beckenham, Kent • Another immensely qualified person loses their job for not being optimistic enough about Brexit.
(9) After 14 years of great lovemaking, an erection causes him immense pain and has terminated our sex life.
(10) Despite the "immense challenges" which Yves Mersch cited today , BNP reckons the ECB will have to take unconventional action to fight off weak inflation and to stimulate growth.
(11) It may be just as well that Hugh Grant fervently believes a film succeeds on its qualities, not on publicity about its stars, because he did his tabloid reputation as a heartless, feather-brained Lothario immense harm in the process of delivering damning testimony on phone-hacking to the Leveson inquiry on Monday.
(12) Immense occupancy and porta hepatis proximity of the cysts were triggers for developing jaundice.
(13) An immensely cerebral man, who trained himself to need only six hours of sleep - believing that a woman should have seven and only a fool eight - Mishcon was not a man given to small talk, nor one who would tolerate prattle for the sake of it.
(14) During the last years of her life, Shearer wrote book reviews (not just of dance books) for the Daily and Sunday Telegraph, which were immensely readable though not celebrated for their generosity towards authors.
(15) Global policymakers know well the immense value of forests – so why have development interventions largely failed to harness the positive contributions of forested landscapes?
(16) Thanet suffers from immense shortages of housing and jobs.
(17) The kinds of skills graduates bring can be immensely valuable.
(18) At such levels, public outrage would be immense, but we are prepared to tolerate such risks from the climate because the prospects of catastrophic levels of warming are still regarded by many as remote, the study suggested, and we are poor at calculating risk.
(19) A case is reported in which an immense cranial vault was reduced as part of the rehabilitation of a patient with severe hydrocephalus who had preservation of the intellect.
(20) Meanwhile volumes two and three of The Gulag Archipelago appeared to less public acclaim than volume one, but confirmed the uniqueness and immensity of that vast enterprise.
Substantial
Definition:
(a.) Belonging to substance; actually existing; real; as, substantial life.
(a.) Not seeming or imaginary; not illusive; real; solid; true; veritable.
(a.) Corporeal; material; firm.
(a.) Having good substance; strong; stout; solid; firm; as, substantial cloth; a substantial fence or wall.
(a.) Possessed of goods or an estate; moderately wealthy; responsible; as, a substantial freeholder.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.