(a.) Not mortal; exempt from liability to die; undying; imperishable; lasting forever; having unlimited, or eternal, existance.
(a.) Connected with, or pertaining to immortability.
(a.) Destined to live in all ages of this world; abiding; exempt from oblivion; imperishable; as, immortal fame.
(a.) Great; excessive; grievous.
(n.) One who will never cease to be; one exempt from death, decay, or annihilation.
Example Sentences:
(1) In keratinocyte lines immortalized by E7 alone, the p53 half-life was found to be similar to that in non-transformed cells; however, it decreased to approximately 1 h following supertransfection of an E6 gene.
(2) This has been accomplished by insertion of a desired gene into a pre-existing immortal cell or by immortalizing primary cells.
(3) The proliferation of this cell type may represent an escape from the senescence pathway and progression to immortal tumor cells.
(4) The large T antigen from both of these viruses can immortalize primary rat embryo fibroblasts.
(5) Normal and E1A-immortalized rat fetal intestinal epithelial SLC-11 cells were compared for the characteristics of the 35S-labeled proteoglycans isolated from their cell-associated and secreted fractions.
(6) Hybrids obtained following fusion of normal human diploid fibroblasts with different immortal human cell lines exhibited limited division potential.
(7) Cell lines established directly from adult T-cell leukemia-lymphoma patients or immortalized by human T-cell leukemia virus type I (HTLV-I) in vitro that do not produce complete HTLV virions were characterized both for the content of viral proteins and for the presence of trans-acting factors activating gene expression under the control of the HTLV long terminal repeat.
(8) Significantly, their derivation demonstrates the feasibility of immortalizing differentiated neurons by targeting tumorigenesis in transgenic mice to specific neurons of the CNS.
(9) We report on the use of human B lymphocytes immortalized by the Epstein-Barr virus (EBV) as targets for transformation by the c-Ha-ras oncogene of bladder carcinoma cells T24.
(10) Mutagenesis of a diploid human fibroblast strain, KD, with the chemical carcinogen 4 nitroquinolin-1-oxide led to the isolation of stably immortalized neoplastic substrains.
(11) Spontaneous outgrowth of immortalized Epstein-Barr virus (EBV) infected B-cell clones will occur from cultures of peripheral blood mononuclear cells (PBMNCs) of some persons with a history of EBV infection.
(12) We have analyzed the antisperm antibody production of autoimmunized male subjects using Epstein-Barr virus (EBV) immortalization of B lymphocytes.
(13) We suggest that the temporal pattern of HSP70 expression during S phase, the nuclear localization, and activation by trans-acting immortalizing proteins indicate a role for HSP70 in the nucleus of replicating cells.
(14) We have previously reported that adenovirus E1a mutants lacking the C-terminal 61 or 67 amino acids were severely defective in immortalization, but cooperated more efficiently (than wt E1a) with activated T24 ras oncogene in transformation of primary rat kidney (BRK) cells (Subramanian et al., 1989; Oncogene, 4:415-420).
(15) Diazepam and medazepam exposure of immortal and low passage number cells resulted in the formation of monopolar mitotic spindles and subsequent metaphase arrest.
(16) In order to elucidate the role of c-myc oncogene activation in B cell malignancy, the phenotypic changes caused by the expression of c-myc oncogenes in human B lymphoblastoid cells immortalized by Epstein-Barr virus were analyzed.
(17) In contrast, we detected no immortalized colonies when we transfected the cells with DNA of five other early-region deletion mutants that do not make stable truncated forms of T antigen.
(18) Celebrities from Justin Bieber to Spike Lee were on hand for the opening of a spectacle that mixes circus tricks with the music of the late King of Pop – a pairing that has already proved lucrative for Cirque on the road with the arena show, Michael Jackson: The Immortal World Tour .
(19) Unlike the mitogen-stimulated Schwann cells, whose proliferation could be inhibited completely, the immortalized and transformed Schwann cell types were nearly unresponsive to the antiproliferative activity.
(20) After dexamethasone removal, immortal cells divided once or twice and then accumulated in G1.
Incorruptible
Definition:
(a.) Not corruptible; incapable of corruption, decay, or dissolution; as, gold is incorruptible.
(a.) Incapable of being bribed or morally corrupted; inflexibly just and upright.
(n.) One of a religious sect which arose in Alexandria, in the reign of the Emperor Justinian, and which believed that the body of Christ was incorruptible, and that he suffered hunger, thirst, pain, only in appearance.
(n.) The quality or state of being incorruptible.
Example Sentences:
(1) Finally the importance of fish will not only increase for economic, but certainly also for ecological reasons, because it is well established as an incorruptible bioindicator of our environment.
(2) In his mid-80s, in his conservatory at home in Essex, he summarised the order of his interests as "travelling, writing and growing lilies"; he travelled before he turned writer, beginning in the relatively incorruptible Spain of the early 1930s, and going on for more than 60 years to observe the ebb and flow of governments, the dissolution of indigenous tribal cultures and the activities of missionaries, bandits, profiteers and political scene-shifters.
(3) "The sharia justice system is swift and incorruptible.
(4) But Mr Putin has ended that disarray and rehabilitated the KGB as the embodiment of the ascetic, incorruptible public service.
(5) Buhari, a tough-talking ex-general with a reputation for incorruptibility, was viewed by many Nigerians as an almost messianic figure who would rescue the country from its kleptocratic ruling elite and crush Boko Haram , the homegrown jihadi group responsible for thousands of deaths in recent years.
(6) To his supporters he is an efficient, tough and incorruptible administrator whose style of economic governance – dubbed " Modinomics " – has worked wonders in Gujarat and can be rolled out across India.
(7) She writes of herself: "Impregnably honest, utterly fearless, incorruptible by the worldly lures which tend to weaken and deflect most reformers, yet sane, scientific and happy, Dr Stopes, hating all conflict, is fighting on behalf of others."
(8) Those super-rich Russians and Chinese – the biggest buyers of investor visas for people committing at least £1m – see a stable political system, an open economy, honest courts and incorruptible officials.
(9) The embassy-provided programme notes described Jiao as “a role model for civil servants with his hardworking, upright, incorruptible personality”.
(10) But after a year in which Boko Haram and government corruption has dominated local headlines, the ex-general has two things going for him: a reputation for strong leadership and incorruptibility.
(11) To punish the oppressors of humanity is clemency; to forgive them is barbarity.” Not a week passes without reference to these statements in the Spanish media: only the other week, the founding editor of the centre-right daily El Mundo sarcastically dubbed Iglesias “The incorruptible senor X” , a reference to Robespierre’s nickname.
(12) Michnik, Lehman said, was "a brave, incorruptible and tolerant Polish rebel who has never tired of speaking out in the European public sphere".
(13) Even his most vicious critics would concede that he is utterly incorruptible; he knows how to handle a global crisis; and he is a genuine devotee of the game.)
(14) But by hollowing out the civil service – historically the only system via which efficient and incorrupt public services were brought into being – this government is set to increase the opportunities for corruption and corporate exploitation of environments chronically prone to market failure while undermining exactly the institutions that might protect the taxpayer.
(15) Glossing over the moderate liberals’ appalling political errors, the standard account traces the Terror to Robespierre’s beliefs: thus emerges the idea that radical democracy, equality and incorruptibility breed violence.
(16) The come-back of a psychopathology of "faculties" linked to the notion of deficiency and reinforced by fascination with computers, also represents the need of humankind to believe in an incorruptible soul.