What's the difference between immunity and variolation?

Immunity


Definition:

  • (a.) Freedom or exemption from any charge, duty, obligation, office, tax, imposition, penalty, or service; a particular privilege; as, the immunities of the free cities of Germany; the immunities of the clergy.
  • (a.) Freedom; exemption; as, immunity from error.

Example Sentences:

  • (1) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
  • (2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
  • (3) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (4) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
  • (5) In addition, this pretreatment protocol did not modify the recipient immune response against B-lymphocyte alloantigens which developed in unsuccessful transplants.
  • (6) within 12 h of birth followed by similar injections every day for 10 consecutive days and then every second day for a further 8 weeks, with mycoplasma broth medium (tolerogen), to induce immune tolerance.
  • (7) The nuclear origin of the Ha antigen was confirmed by the speckled nuclear immunofluorescence staining pattern given by purified antibody to Ha obtained from a specific immune precipitate.
  • (8) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (9) We postulate that FAA may affect the human peripheral and mucosal immune system.
  • (10) Attempts are now being made to use this increased understanding to produce effective killed vaccines that produce immune responses in the lung.
  • (11) These data indicate that RNA faithfully transfers "suppressive" as well as "positive" types of immune responses that have been reported previously for lymphocytes obtained directly from tumour-bearing and tumour-immune animals.
  • (12) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
  • (13) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
  • (14) These same molecules may be equally responsible for the pathologic characteristics of the immune response seen, for example, in inflammatory bowel diseases.
  • (15) The literature on depression and immunity is reviewed and the clinical implications of our findings are discussed.
  • (16) These results suggest that CD4+ protective T cells generated by immunization with vBCG are characterized by the ability to produce IFN-gamma after stimulation with specific Ag.
  • (17) All of the rabbits immunized with FCA developed sterile subcutaneous abscesses.
  • (18) We conclude that both exogenously applied PAF by inhalation and antigen exposure are capable of inducing LAR in sensitized guinea pigs, and thus the priming effect of immunization and PAF may contribute to the development of LAR observed in asthma.
  • (19) Its pathogenesis, still incompletely elucidated, involves the precipitation of immune complexes in the walls of the all vessels.
  • (20) Our results on humoral and cellular components of immunity in dependence of age, according to SENIEUR protocol admission criteria are presented.

Variolation


Definition:

  • (n.) Inoculation with smallpox.

Example Sentences:

  • (1) With smallpox, the variolation (since 1730) gave first relief, until Sir Edward Jenner discovered in 1798 the highly successful cross-immunity through vaccination.
  • (2) Smallpox vaccination was known as variolation before the modern practice of vaccination with cowpox (Vaccinia) was demonstrated in 1796.
  • (3) Man's first attempt to immunize susceptibles against smallpox infection was by variolation, a practice which could be traced back several thousand years.
  • (4) Variolation is an ancient method of protection against naturally acquired smallpox that was officially proscribed in the early 1950s but was renewed in remote areas when smallpox vaccination activities were interrupted during the three-year famine of 1959-1962, following the "great leap forward" program of 1958.
  • (5) The last known cases occurred in 1965, and the practice of variolation is now believed to be extinct.
  • (6) The health authorities responded by capturing the variolators, confiscating their variolation material and equipment, and vaccinating the population.
  • (7) Fear of smallpox provoked the first important attempts to prevent epidemic disease by a primitive form of immunization called variolation.
  • (8) All were among persons who had been variolated or were their close contacts.
  • (9) It is ironic that smallpox became an epidemic pestilence upon the growth of populations, yet it played a major role in preventing population growth until variolation and vaccination became common.
  • (10) It was found that the variolators in Shanxi Province and Nei Monggol Autonomous Region inoculated persons with the use of powdered smallpox scabs mixed with human milk, and that they obtained fresh supplies of scabs every 6-12 months by variolating relatives and friends.
  • (11) Smallpox existed in Romania since the 17th century, when both variolation and vaccinia were used for preventing the disease.
  • (12) Tissot's influence manifested itself also in the early introduction of variolation.